Multiple Mammarenaviruses Circulating in Angolan Rodents

J 2021

Multiple Mammarenaviruses Circulating in Angolan Rodents

TĚŠÍKOVÁ, Jana; Jarmila KRÁSOVÁ a Joëlle,Marie,Chantal GOÜY DE BELLOCQ FEUQUIERES

Základní údaje

Originální název

Multiple Mammarenaviruses Circulating in Angolan Rodents

Autoři

TĚŠÍKOVÁ, Jana; Jarmila KRÁSOVÁ a Joëlle,Marie,Chantal GOÜY DE BELLOCQ FEUQUIERES

Vydání

Viruses, Basel, MDPI, 2021, 1999-4915

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10607 Virology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.818

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/21:00122139

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

mammarenaviruses; hantaviruses; Angola; Mastomys natalensis; Micaelamys namaquensis; Mus triton; phylogeny

Štítky

14314020, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 1. 2022 13:36, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Rodents are a speciose group of mammals with strong zoonotic potential. Some parts of Africa are still underexplored for the occurrence of rodent-borne pathogens, despite this high potential. Angola is at the convergence of three major biogeographical regions of sub-Saharan Africa, each harbouring a specific rodent community. This rodent-rich area is, therefore, strategic for studying the diversity and evolution of rodent-borne viruses. In this study we examined 290 small mammals, almost all rodents, for the presence of mammarenavirus and hantavirus RNA. While no hantavirus was detected, we found three rodent species positive for distinct mammarenaviruses with a particularly high prevalence in Namaqua rock rats (Micaelamys namaquensis). We characterised four complete virus genomes, which showed typical mammarenavirus organisation. Phylogenetic and genetic distance analyses revealed: (i) the presence of a significantly divergent strain of Luna virus in Angolan representatives of the ubiquitous Natal multimammate mouse (Mastomys natalensis), (ii) a novel Okahandja-related virus associated with the Angolan lineage of Micaelamys namaquensis for which we propose the name Bitu virus (BITV) and (iii) the occurrence of a novel Mobala-like mammarenavirus in the grey-bellied pygmy mouse (Mus triton) for which we propose the name Kwanza virus (KWAV). This high virus diversity in a limited host sample size and in a relatively small geographical area supports the idea that Angola is a hotspot for mammarenavirus diversity.

Návaznosti

LM2018140, projekt VaV

Název: e-Infrastruktura CZ (Akronym: e-INFRA CZ)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, e-Infrastruktura CZ

Citovat

TĚŠÍKOVÁ, Jana; Jarmila KRÁSOVÁ a Joëlle,Marie,Chantal GOÜY DE BELLOCQ FEUQUIERES. Multiple Mammarenaviruses Circulating in Angolan Rodents. Viruses. Basel: MDPI, 2021, roč. 13, č. 6, s. 1-13. ISSN 1999-4915. Dostupné z: https://doi.org/10.3390/v13060982.

@article{1786959,
   author = {Těšíková, Jana and Krásová, Jarmila and Goüy de Bellocq Feuquieres, Joëlle,Marie,Chantal},
   article_location = {Basel},
   article_number = {6},
   doi = {https://doi.org/10.3390/v13060982},
   keywords = {mammarenaviruses; hantaviruses; Angola; Mastomys natalensis; Micaelamys namaquensis; Mus triton; phylogeny},
   language = {eng},
   issn = {1999-4915},
   journal = {Viruses},
   title = {Multiple Mammarenaviruses Circulating in Angolan Rodents},
   url = {https://www.mdpi.com/1999-4915/13/6/982},
   volume = {13},
   year = {2021}
}

TY  - JOUR
ID  - 1786959
AU  - Těšíková, Jana - Krásová, Jarmila - Goüy de Bellocq Feuquieres, Joëlle,Marie,Chantal
PY  - 2021
TI  - Multiple Mammarenaviruses Circulating in Angolan Rodents
JF  - Viruses
VL  - 13
IS  - 6
SP  - 1-13
EP  - 1-13
PB  - MDPI
SN  - 19994915
KW  - mammarenaviruses
KW  - hantaviruses
KW  - Angola
KW  - Mastomys natalensis
KW  - Micaelamys namaquensis
KW  - Mus triton
KW  - phylogeny
UR  - https://www.mdpi.com/1999-4915/13/6/982
N2  - Rodents are a speciose group of mammals with strong zoonotic potential. Some parts of Africa are still underexplored for the occurrence of rodent-borne pathogens, despite this high potential. Angola is at the convergence of three major biogeographical regions of sub-Saharan Africa, each harbouring a specific rodent community. This rodent-rich area is, therefore, strategic for studying the diversity and evolution of rodent-borne viruses. In this study we examined 290 small mammals, almost all rodents, for the presence of mammarenavirus and hantavirus RNA. While no hantavirus was detected, we found three rodent species positive for distinct mammarenaviruses with a particularly high prevalence in Namaqua rock rats (Micaelamys namaquensis). We characterised four complete virus genomes, which showed typical mammarenavirus organisation. Phylogenetic and genetic distance analyses revealed: (i) the presence of a significantly divergent strain of Luna virus in Angolan representatives of the ubiquitous Natal multimammate mouse (Mastomys natalensis), (ii) a novel Okahandja-related virus associated with the Angolan lineage of Micaelamys namaquensis for which we propose the name Bitu virus (BITV) and (iii) the occurrence of a novel Mobala-like mammarenavirus in the grey-bellied pygmy mouse (Mus triton) for which we propose the name Kwanza virus (KWAV). This high virus diversity in a limited host sample size and in a relatively small geographical area supports the idea that Angola is a hotspot for mammarenavirus diversity.
ER  -

TĚŠÍKOVÁ, Jana; Jarmila KRÁSOVÁ a Jo$\backslash$''elle,Marie,Chantal GOÜY DE BELLOCQ FEUQUIERES. Multiple Mammarenaviruses Circulating in Angolan Rodents. \textit{Viruses}. Basel: MDPI, 2021, roč.~13, č.~6, s.~1-13. ISSN~1999-4915. Dostupné z: https://doi.org/10.3390/v13060982.

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