J 2021

GA4GH: International policies and standards for data sharing across genomic research and healthcare

REHM, Heidi; Angela PAGE; Lindsay SMITH; Jeremy ADAMS; Gil ALTEROVITZ et al.

Základní údaje

Originální název

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Autoři

REHM, Heidi; Angela PAGE; Lindsay SMITH; Jeremy ADAMS; Gil ALTEROVITZ; Lawrence BABB; Maxmillian BARKLEY; Michael BAUDIS; Michael BEAUVAIS; Tim BECK; Jacques BECKMANN; Sergi BELTRAN; David BERNICK; Alexander BERNIER; James BONFIELD; Tiffany BOUGHTWOOD; Guillaume BOURQUE; Sarion BOWERS; Anthony BROOKES; Michael BRUDNO; Matthew BRUSH; David BUJOLD; Tony BURDETT; Orion BUSKE; Moran CABILI; Daniel CAMERON; Robert CARROLL; Esmeralda CASAS-SILVA; Debyani CHAKRAVARTY; Bimal CHAUDHARI; Shu Hui CHEN; Michael CHERRY; Justina CHUNG; Melissa CLINE; Hayley CLISSOLD; Robert COOK-DEEGAN; Mélanie COURTOT; Fiona CUNNINGHAM; Miro CUPAK; Robert DAVIES; Danielle DENISKO; Megan DOERR; Lena DOLMAN; Edward DOVE; Jonathan DURSI; Stephanie DYKE; James EDDY; Karen EILBECK; Kyle ELLROTT; Susan FAIRLEY; Khalid FAKHRO; Helen FIRTH; Michael FITZSIMONS; Marc FIUME; Paul FLICEK; Ian FORE; Mallory FREEBERG; Robert FREIMUTH; Lauren FROMONT; Jonathan FUERTH; Clara GAFF; Weiniu GAN; Elena GHANAIM; David GLAZER; Robert GREEN; Malachi GRIFFITH; Obi GRIFFITH; Robert GROSSMAN; Tudor GROZA; Jaime Guidry AUVIL; Roderic GUIGÓ; Dipayan GUPTA; Melissa HAENDEL; Ada HAMOSH; David HANSEN; Reece HART; Dean Mitchell HARTLEY; David HAUSSLER; Rachele HENDRICKS-STURRUP; Calvin HO; Ashley HOBB; Michael HOFFMAN; Oliver HOFMANN; Petr HOLUB; Jacob Shujui HSU; Jean-Pierre HUBAUX; Sarah HUNT; Ammar HUSAMI; Julius JACOBSEN; Saumya JAMUAR; Elizabeth JANES; Francis JEANSON; Aina JENÉ; Amber JOHNS; Yann JOLY; Steven JONES; Alexander KANITZ; Kazuto KATO; Thomas KEANE; Kristina KEKESI-LAFRANCE; Jerome KELLEHER; Giselle KERRY; Seik-Soon KHOR; Bartha KNOPPERS; Melissa KONOPKO; Kenjiro KOSAKI; Martin KUBA; Jonathan LAWSON; Rasko LEINONEN; Stephanie LI; Michael LIN; Mikael LINDEN; Xianglin LIU; Isuru Udara LIYANAGE; Javier LOPEZ; Anneke LUCASSEN; Michael LUKOWSKI; Alice MANN; John MARSHALL; Michele MATTIONI; Alejandro METKE-JIMENEZ; Anna MIDDLETON; Richard MILNE; Fruzsina MOLNÁR-GÁBOR; Nicola MULDER; Monica MUNOZ-TORRES; Rishi NAG; Hidewaki NAKAGAWA; Jamal NASIR; Arcadi NAVARRO; Tristan NELSON; Ania NIEWIELSKA; Amy NISSELLE; Jeffrey NIU; Tommi NYRÖNEN; O Connor BRIAN; Sabine OESTERLE; Soichi OGISHIMA; Vivian Ota WANG; Laura PAGLIONE; Emilio PALUMBO; Helen PARKINSON; Anthony PHILIPPAKIS; Angel PIZARRO; Andreas PRLIC; Jordi RAMBLA; Augusto RENDON; Renee RIDER; Peter ROBINSON; Kurt RODARMER; Laura Lyman RODRIGUEZ; Alan RUBIN; Manuel RUEDA; Gregory RUSHTON; Rosalyn RYAN; Gary SAUNDERS; Helen SCHUILENBURG; Torsten SCHWEDE; Serena SCOLLEN; Alexander SENF; Nathan SHEFFIELD; Neerjah SKANTHARAJAH; Albert SMITH; Heidi SOFIA; Dylan SPALDING; Amanda SPURDLE; Zornitza STARK; Lincoln STEIN; Makoto SUEMATSU; Patrick TAN; Jonathan TEDDS; Alastair THOMSON; Adrian THOROGOOD; Timothy TICKLE; Katsushi TOKUNAGA; Juha TÖRNROOS; David TORRENTS; Sean UPCHURCH; Alfonso VALENCIA; Roman VALLS GUIMERA; Jessica VAMATHEVAN; Susheel VARMA; Danya VEARS; Coby VINER; Craig VOISIN; Alex WAGNER; Susan WALLACE; Brian WALSH; Marc WILLIAMS; Eva WINKLER; Barbara WOLD; Grant WOOD; Patrick WOOLLEY; Chisato YAMASAKI; Andrew YATES; Christina YUNG; Lyndon ZASS; Ksenia ZAYTSEVA; Junjun ZHANG; Peter GOODHAND; Kathryn NORTH a Ewan BIRNEY

Vydání

Cell Genomics, Cell Press, 2021, 2666-979X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10201 Computer sciences, information science, bioinformatics

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14610/21:00140150

Organizační jednotka

Ústav výpočetní techniky

Klíčová slova anglicky

CLINICAL LABORATORIESMATCHMAKER EXCHANGEPRECISION MEDICINECANCERBIOBANKDISCOVERYCLASSIFICATIONMUTATIONSSCIENCECLINVAR

Štítky

Změněno: 26. 3. 2026 16:05, Mgr. Eva Špillingová

Anotace

V originále

The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic sequencing (along with other genome-widemolecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions of humans, with increasing levels of diversity. In this perspective, we present the GA4GH strategies for addressing the major challenges of this data revolution. We describe the GA4GH organization, which is fueled by the development efforts of eight Work Streams and informed by the needs of 24 Driver Projects and other key stakeholders. We present the GA4GH suite of secure, interoperable technical standards and policy frameworks and review the current status of standards, their relevance to key domains of research and clinical care, and future plans of GA4GH. Broad international participation in building, adopting, and deploying GA4GH standards and frameworks will catalyze an unprecedented effort in data sharing that will be critical to advancing genomic medicine and ensuring that all populations can access its benefits.