Genetic characterization of nodular worm infections in Asian
Apes

J 2021

Genetic characterization of nodular worm infections in Asian Apes

YALCINDAG, Erhan, Peter Daniel STUART, Hideo HASEGAWA, Adrian STREIT, Jana DOLEŽALOVÁ et. al.

Základní údaje

Originální název

Genetic characterization of nodular worm infections in Asian Apes

Autoři

YALCINDAG, Erhan (792 Turecko, domácí), Peter Daniel STUART (372 Irsko, domácí), Hideo HASEGAWA, Adrian STREIT, Jana DOLEŽALOVÁ, Helen MORROGH-BERNARD, Susan M. CHEYNE, Wisnu NURCAHYO a Ivona FOITOVÁ (203 Česká republika, garant, domácí)

Vydání

Nature Scientific Reports, Nature Research, 2021, 2045-2322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10613 Zoology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.996

Kód RIV

RIV/00216224:14310/21:00119403

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1038/s41598-021-86518-2

UT WoS

000684826700007

Klíčová slova anglicky

Intestinal parasites; nodular worms; parasitic nematodes; Oesophagostomum; Southeast Asia; orangutans; gibbons

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 12. 2021 13:53, Mgr. Marie Šípková, DiS.

Anotace

V originále

Parasitic nematodes of Oesophagostomum spp., commonly known, as 'nodular worms' are emerging as the most widely distributed and prevalent zoonotic nematodes. Oesophagostomum infections are well documented in African non-human primates; however, the taxonomy, distribution and transmission of Oesophagostomum in Asian non-human primates are not adequately studied. To better understand which Oesophagostomum species infect Asian non-human primates and determine their phylogeny we analysed 55 faecal samples from 50 orangutan and 5 gibbon individuals from Borneo and Sumatra. Both microscopy and molecular results revealed that semi-wild animals had higher Oesophagostomum infection prevalence than free ranging animals. Based on sequence genotyping analysis targeting the Internal transcribed spacer 2 of rDNA, we report for the first time the presence of O. aculeatum in Sumatran apes. Population genetic analysis shows that there is significant genetic differentiation between Bornean and Sumatran O. aculeatum populations. Our results clearly reveal that O. aculeatum in free-ranging animals have a higher genetic variation than those in semi-wild animals, demonstrating that O. aculeatum is circulating naturally in wildlife and zoonotic transmission is possible. Further studies should be conducted to better understand the epidemiology and dynamics of Oesophagostomum transmission between humans, non-human primates and other wild species and livestock in Southeast Asia.

Návaznosti

EE2.3.30.0009, projekt VaV

Název: Zaměstnáním čerstvých absolventů doktorského studia k vědecké excelenci

EE2.3.30.0037, projekt VaV

Název: Zaměstnáním nejlepších mladých vědců k rozvoji mezinárodní spolupráce

GAP505/11/1163, projekt VaV

Název: Protizánětlivá aktivita extraktů z rostlin Indonésie a jejich účinek na průběh oportunních parazitóz

Investor: Grantová agentura ČR, Protizánětlivá aktivita extraktů z rostlin Indonésie a jejich účinek na průběh oportunních parazitóz

Citovat

YALCINDAG, Erhan, Peter Daniel STUART, Hideo HASEGAWA, Adrian STREIT, Jana DOLEŽALOVÁ, Helen MORROGH-BERNARD, Susan M. CHEYNE, Wisnu NURCAHYO a Ivona FOITOVÁ. Genetic characterization of nodular worm infections in Asian Apes. Nature Scientific Reports. Nature Research, 2021, roč. 11, č. 1, s. 7226-7236. ISSN 2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-021-86518-2.

@article{1808288,
   author = {Yalcindag, Erhan and Stuart, Peter Daniel and Hasegawa, Hideo and Streit, Adrian and Doležalová, Jana and MorroghandBernard, Helen and Cheyne, Susan M. and Nurcahyo, Wisnu and Foitová, Ivona},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s41598-021-86518-2},
   keywords = {Intestinal parasites; nodular worms; parasitic nematodes; Oesophagostomum; Southeast Asia; orangutans; gibbons},
   language = {eng},
   issn = {2045-2322},
   journal = {Nature Scientific Reports},
   title = {Genetic characterization of nodular worm infections in Asian Apes},
   url = {https://www.nature.com/articles/s41598-021-86518-2#citeas},
   volume = {11},
   year = {2021}
}

TY  - JOUR
ID  - 1808288
AU  - Yalcindag, Erhan - Stuart, Peter Daniel - Hasegawa, Hideo - Streit, Adrian - Doležalová, Jana - Morrogh-Bernard, Helen - Cheyne, Susan M. - Nurcahyo, Wisnu - Foitová, Ivona
PY  - 2021
TI  - Genetic characterization of nodular worm infections in Asian Apes
JF  - Nature Scientific Reports
VL  - 11
IS  - 1
SP  - 7226
EP  - 7226
PB  - Nature Research
SN  - 20452322
KW  - Intestinal parasites
KW  - nodular worms
KW  - parasitic nematodes
KW  - Oesophagostomum
KW  - Southeast Asia
KW  - orangutans
KW  - gibbons
UR  - https://www.nature.com/articles/s41598-021-86518-2#citeas
N2  - Parasitic nematodes of Oesophagostomum spp., commonly known, as 'nodular worms' are emerging as the most widely distributed and prevalent zoonotic nematodes. Oesophagostomum infections are well documented in African non-human primates; however, the taxonomy, distribution and transmission of Oesophagostomum in Asian non-human primates are not adequately studied. To better understand which Oesophagostomum species infect Asian non-human primates and determine their phylogeny we analysed 55 faecal samples from 50 orangutan and 5 gibbon individuals from Borneo and Sumatra. Both microscopy and molecular results revealed that semi-wild animals had higher Oesophagostomum infection prevalence than free ranging animals. Based on sequence genotyping analysis targeting the Internal transcribed spacer 2 of rDNA, we report for the first time the presence of O. aculeatum in Sumatran apes. Population genetic analysis shows that there is significant genetic differentiation between Bornean and Sumatran O. aculeatum populations. Our results clearly reveal that O. aculeatum in free-ranging animals have a higher genetic variation than those in semi-wild animals, demonstrating that O. aculeatum is circulating naturally in wildlife and zoonotic transmission is possible. Further studies should be conducted to better understand the epidemiology and dynamics of Oesophagostomum transmission between humans, non-human primates and other wild species and livestock in Southeast Asia.
ER  -

YALCINDAG, Erhan, Peter Daniel STUART, Hideo HASEGAWA, Adrian STREIT, Jana DOLEŽALOVÁ, Helen MORROGH-BERNARD, Susan M. CHEYNE, Wisnu NURCAHYO a Ivona FOITOVÁ. Genetic characterization of nodular worm infections in Asian Apes. \textit{Nature Scientific Reports}. Nature Research, 2021, roč.~11, č.~1, s.~7226-7236. ISSN~2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-021-86518-2.

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