Recent findings on perinatal mesenchymal stem cells - their
possible application in current advanced medicine

J 2021

Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine

SIBIAK, Rafał; Katarzyna STEFAŃSKA; Kornel RATAJCZAK; Dorota BUKOWSKA; Paweł ANTOSIK et al.

Základní údaje

Originální název

Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine

Autoři

SIBIAK, Rafał; Katarzyna STEFAŃSKA; Kornel RATAJCZAK; Dorota BUKOWSKA; Paweł ANTOSIK; Paul MOZDZIAK a Michal JEŠETA

Vydání

Medical Journal of Cell Biology, Warsaw, Walter de Gruyter, 2021, 2544-3577

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10601 Cell biology

Stát vydavatele

Polsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/21:00123198

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.2478/acb-2021-0008

EID Scopus

2-s2.0-85109154892

Klíčová slova anglicky

human; perinatal mesenchymal stem cells; placental mesenchymal stem cells; umbilical cord mesenchymal stem cells

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 12. 2021 09:06, Mgr. Tereza Miškechová

Anotace

V originále

The mature human placenta and umbilical cord are rich sources of perinatal mesenchymal stem cells (MSCs). Both cell populations have similar characteristics and cellular properties. Each population can differentiate into multiple mesenchymal subpopulations and retain their self-renewal capacities. Perinatal stem cells can be isolated from tissues obtained from the planned cesarean sections and vaginal deliveries. Their isolation is relatively easy, making them readily available for implementation in various in vitro studies and clinical trials. Their differentiation abilities could be used in advanced regenerative medicine protocols to form new bone, cartilage, or tendons. Moreover, their unique anti-inflammatory and immunomodulatory properties have been implemented in the experimental treatment of multiple autoimmune and degenerative diseases. Numerous phase I/II clinical trials confirmed the safety of perinatal MSCs injections and infusions, albeit the efficacy of those cellular therapies should be investigated in the subsequent large-scale randomized trials. Running title: Clinical applications of the perinatal mesenchymal stem cells.

Citovat

SIBIAK, Rafał; Katarzyna STEFAŃSKA; Kornel RATAJCZAK; Dorota BUKOWSKA; Paweł ANTOSIK; Paul MOZDZIAK a Michal JEŠETA. Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine. Medical Journal of Cell Biology. Warsaw: Walter de Gruyter, 2021, roč. 9, č. 2, s. 48-55. ISSN 2544-3577. Dostupné z: https://doi.org/10.2478/acb-2021-0008.

@article{1808502,
   author = {Sibiak, Rafał and Stefańska, Katarzyna and Ratajczak, Kornel and Bukowska, Dorota and Antosik, Paweł and Mozdziak, Paul and Ješeta, Michal},
   article_location = {Warsaw},
   article_number = {2},
   doi = {https://doi.org/10.2478/acb-2021-0008},
   keywords = {human; perinatal mesenchymal stem cells; placental mesenchymal stem cells; umbilical cord mesenchymal stem cells},
   language = {eng},
   issn = {2544-3577},
   journal = {Medical Journal of Cell Biology},
   title = {Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine},
   url = {https://www.sciendo.com/article/10.2478/acb-2021-0008},
   volume = {9},
   year = {2021}
}

TY  - JOUR
ID  - 1808502
AU  - Sibiak, Rafał - Stefańska, Katarzyna - Ratajczak, Kornel - Bukowska, Dorota - Antosik, Paweł - Mozdziak, Paul - Ješeta, Michal
PY  - 2021
TI  - Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine
JF  - Medical Journal of Cell Biology
VL  - 9
IS  - 2
SP  - 48-55
EP  - 48-55
PB  - Walter de Gruyter
SN  - 25443577
KW  - human
KW  - perinatal mesenchymal stem cells
KW  - placental mesenchymal stem cells
KW  - umbilical cord mesenchymal stem cells
UR  - https://www.sciendo.com/article/10.2478/acb-2021-0008
N2  - The mature human placenta and umbilical cord are rich sources of perinatal mesenchymal stem cells (MSCs). Both cell populations have similar characteristics and cellular properties. Each population can differentiate into multiple mesenchymal subpopulations and retain their self-renewal capacities. Perinatal stem cells can be isolated from tissues obtained from the planned cesarean sections and vaginal deliveries. Their isolation is relatively easy, making them readily available for implementation in various in vitro studies and clinical trials. Their differentiation abilities could be used in advanced regenerative medicine protocols to form new bone, cartilage, or tendons. Moreover, their unique anti-inflammatory and immunomodulatory properties have been implemented in the experimental treatment of multiple autoimmune and degenerative diseases. Numerous phase I/II clinical trials confirmed the safety of perinatal MSCs injections and infusions, albeit the efficacy of those cellular therapies should be investigated in the subsequent large-scale randomized trials. Running title: Clinical applications of the perinatal mesenchymal stem cells.
ER  -

SIBIAK, Rafał; Katarzyna STEFA$\backslash$'NSKA; Kornel RATAJCZAK; Dorota BUKOWSKA; Paweł ANTOSIK; Paul MOZDZIAK a Michal JEŠETA. Recent findings on perinatal mesenchymal stem cells - their possible application in current advanced medicine. \textit{Medical Journal of Cell Biology}. Warsaw: Walter de Gruyter, 2021, roč.~9, č.~2, s.~48-55. ISSN~2544-3577. Dostupné z: https://doi.org/10.2478/acb-2021-0008.

Přehled o publikaci