Progressive Tumefactive Demyelination as the Only Result of
Extensive Diagnostic Work-Up: A Case Report

J 2021

Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report

ŠTOURAČ, Pavel; Jan KOLČAVA; Miloš KEŘKOVSKÝ; Tereza KOPŘIVOVÁ; Leoš KŘEN et al.

Základní údaje

Originální název

Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report

Autoři

ŠTOURAČ, Pavel; Jan KOLČAVA; Miloš KEŘKOVSKÝ; Tereza KOPŘIVOVÁ; Leoš KŘEN a Josef BEDNAŘÍK

Vydání

Frontiers in Neurology, Lausanne, Frontiers, 2021, 1664-2295

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.086

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/21:00123210

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

demyelinating diseases; multiple sclerosis; neuropathology; neuroradiology; case report

Štítky

14110216, 14110221, 14110230, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 12. 2021 14:34, Mgr. Tereza Miškechová

Anotace

V originále

Tumefactive demyelinating lesions belong to the rare variants of multiple sclerosis, posing a diagnostic challenge since it is difficult to distinguish them from a neoplasm or other brain lesions and they require a careful differential diagnosis. This contribution presents the case report of a young female with progressive tumefactive demyelinating brain and spinal cord lesions. An extensive diagnostic process including two brain biopsies and an autopsy did not reveal any explanatory diagnosis other than multiple sclerosis. The patient was treated by various disease-modifying treatments without significant effect and died from ascendent infection via ventriculoperitoneal shunt resulting in Staphylococcus aureus meningitis.

Návaznosti

MUNI/A/1600/2020, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti (Akronym: PNB)

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti

Citovat

ŠTOURAČ, Pavel; Jan KOLČAVA; Miloš KEŘKOVSKÝ; Tereza KOPŘIVOVÁ; Leoš KŘEN a Josef BEDNAŘÍK. Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report. Frontiers in Neurology. Lausanne: Frontiers, 2021, roč. 12, July 2021, s. 1-4. ISSN 1664-2295. Dostupné z: https://doi.org/10.3389/fneur.2021.701663.

@article{1808667,
   author = {Štourač, Pavel and Kolčava, Jan and Keřkovský, Miloš and Kopřivová, Tereza and Křen, Leoš and Bednařík, Josef},
   article_location = {Lausanne},
   article_number = {July 2021},
   doi = {https://doi.org/10.3389/fneur.2021.701663},
   keywords = {demyelinating diseases; multiple sclerosis; neuropathology; neuroradiology; case report},
   language = {eng},
   issn = {1664-2295},
   journal = {Frontiers in Neurology},
   title = {Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report},
   url = {https://www.frontiersin.org/articles/10.3389/fneur.2021.701663/full},
   volume = {12},
   year = {2021}
}

TY  - JOUR
ID  - 1808667
AU  - Štourač, Pavel - Kolčava, Jan - Keřkovský, Miloš - Kopřivová, Tereza - Křen, Leoš - Bednařík, Josef
PY  - 2021
TI  - Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report
JF  - Frontiers in Neurology
VL  - 12
IS  - July 2021
SP  - 1-4
EP  - 1-4
PB  - Frontiers
SN  - 16642295
KW  - demyelinating diseases
KW  - multiple sclerosis
KW  - neuropathology
KW  - neuroradiology
KW  - case report
UR  - https://www.frontiersin.org/articles/10.3389/fneur.2021.701663/full
N2  - Tumefactive demyelinating lesions belong to the rare variants of multiple sclerosis, posing a diagnostic challenge since it is difficult to distinguish them from a neoplasm or other brain lesions and they require a careful differential diagnosis. This contribution presents the case report of a young female with progressive tumefactive demyelinating brain and spinal cord lesions. An extensive diagnostic process including two brain biopsies and an autopsy did not reveal any explanatory diagnosis other than multiple sclerosis. The patient was treated by various disease-modifying treatments without significant effect and died from ascendent infection via ventriculoperitoneal shunt resulting in Staphylococcus aureus meningitis.
ER  -

ŠTOURAČ, Pavel; Jan KOLČAVA; Miloš KEŘKOVSKÝ; Tereza KOPŘIVOVÁ; Leoš KŘEN a Josef BEDNAŘÍK. Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report. \textit{Frontiers in Neurology}. Lausanne: Frontiers, 2021, roč.~12, July 2021, s.~1-4. ISSN~1664-2295. Dostupné z: https://doi.org/10.3389/fneur.2021.701663.

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