J 2021

Endocrine disrupting chemicals and their detection in an IVF laboratory

JEŠETA, Michal; Kateřina FRANZOVÁ; Lenka MEKIŇOVÁ; Elena KISTANOVA; Peter HARBULÁK et al.

Základní údaje

Originální název

Endocrine disrupting chemicals and their detection in an IVF laboratory

Autoři

JEŠETA, Michal; Kateřina FRANZOVÁ; Lenka MEKIŇOVÁ; Elena KISTANOVA; Peter HARBULÁK; Jana ŽÁKOVÁ; Eva LOUSOVÁ; Pavel VENTRUBA a Igor CRHA

Vydání

Medical Journal of Cell Biology, Warwaw, Walter de Gruyter, 2021, 2544-3577

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10601 Cell biology

Stát vydavatele

Polsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/21:00125195

Organizační jednotka

Lékařská fakulta

EID Scopus

Klíčová slova anglicky

bisphenol; reproduction; endocrine disruptors; oocyte; spermatozoa

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 6. 2. 2023 09:27, Mgr. Tereza Miškechová

Anotace

V originále

The endocrine disruptors are chemicals with the capacity to influence physiological processes in the or-ganism, most often through hormonal control. They are present in the environment and in the products of daily use. They are often found in food, released from plastic bottles for water, present in cosmetics or fertilizers. Latest research suggests that they can be released from plastics used in the IVF laboratories and can be even present in the manipulation and cultivation media used for isolation and fertilization of gametes and subsequent cultivation of embryos. Permanent and long-term utilization of these substan-ces has adverse effects in human reproductive health, mainly by the means of interfering with synthesis and action mechanisms of reproductive hormones. Moreover, some endocrine disruptors show a range of adverse effects directly on the gametes or embryos cultured in the in vitro conditions. The article provides an overview on bisphenols detected in plastics and media commonly used in the IVF laboratory and consi-ders their possible impact on effectiveness of the IVF methods in a human laboratory.