2021
Endocrine disrupting chemicals and their detection in an IVF laboratory
JEŠETA, Michal; Kateřina FRANZOVÁ; Lenka MEKIŇOVÁ; Elena KISTANOVA; Peter HARBULÁK et al.Základní údaje
Originální název
Endocrine disrupting chemicals and their detection in an IVF laboratory
Autoři
JEŠETA, Michal; Kateřina FRANZOVÁ; Lenka MEKIŇOVÁ; Elena KISTANOVA; Peter HARBULÁK; Jana ŽÁKOVÁ; Eva LOUSOVÁ; Pavel VENTRUBA a Igor CRHA
Vydání
Medical Journal of Cell Biology, Warwaw, Walter de Gruyter, 2021, 2544-3577
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
10601 Cell biology
Stát vydavatele
Polsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/21:00125195
Organizační jednotka
Lékařská fakulta
EID Scopus
Klíčová slova anglicky
bisphenol; reproduction; endocrine disruptors; oocyte; spermatozoa
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 6. 2. 2023 09:27, Mgr. Tereza Miškechová
Anotace
V originále
The endocrine disruptors are chemicals with the capacity to influence physiological processes in the or-ganism, most often through hormonal control. They are present in the environment and in the products of daily use. They are often found in food, released from plastic bottles for water, present in cosmetics or fertilizers. Latest research suggests that they can be released from plastics used in the IVF laboratories and can be even present in the manipulation and cultivation media used for isolation and fertilization of gametes and subsequent cultivation of embryos. Permanent and long-term utilization of these substan-ces has adverse effects in human reproductive health, mainly by the means of interfering with synthesis and action mechanisms of reproductive hormones. Moreover, some endocrine disruptors show a range of adverse effects directly on the gametes or embryos cultured in the in vitro conditions. The article provides an overview on bisphenols detected in plastics and media commonly used in the IVF laboratory and consi-ders their possible impact on effectiveness of the IVF methods in a human laboratory.