Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic
Guanosine Monophosphate on Mineral Surfaces

J 2021

Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces

ŠPONEROVÁ, Judit, Jiří ŠPONER, Jakub VÝRAVSKÝ, Ondrej ŠEDO, Zbyněk ZDRÁHAL et. al.

Základní údaje

Originální název

Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces

Autoři

ŠPONEROVÁ, Judit (348 Maďarsko), Jiří ŠPONER (203 Česká republika), Jakub VÝRAVSKÝ (203 Česká republika, domácí), Ondrej ŠEDO (203 Česká republika, domácí), Zbyněk ZDRÁHAL (203 Česká republika, garant, domácí), Giovanna COSTANZO (380 Itálie), Ernesto DI MAURO (380 Itálie), Sreekar WUNNAVA (276 Německo), Dieter BRAUN (276 Německo), Roman MATYÁŠEK (203 Česká republika) a Aleš KOVAŘÍK (203 Česká republika)

Vydání

ChemSystemsChem, Wiley, 2021, 2570-4206

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10400 1.4 Chemical sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

fulltext

Kód RIV

RIV/00216224:14310/21:00119600

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1002/syst.202100017

UT WoS

000671941700001

Klíčová slova anglicky

minerals; nucleotides; oligomerization; oligonucleotides; self-assembly

Štítky

CF PROT, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 11. 2024 20:38, Ing. Martina Blahová

Anotace

V originále

Previous studies on the polymerization of 3',5' cyclic guanosine monophosphate (cGMP) demonstrated the potential of the compound in the abiotic generation of the first oligonucleotide sequences on the early Earth. These experiments were conducted under idealized laboratory conditions, which logically raises the question whether the same chemistry could take place in the harsh environment present on our planet in its earliest days. In the current study, we focus on the mineralogical context of this chemistry and show that numerous, but not all, common minerals assumed to be present on the early Earth could host the polymerization of H-form 3',5' cGMP. In particular, we have found that quartz varieties are especially suitable for this purpose, similar to andalusite, amphibole or micas. On the contrary, olivine, calcite, and serpentine-group minerals interfere with the studied polymerization chemistry. Our results show that crystallization on mineral surfaces, which is mainly a diffusion controlled process, determines the ability of 3',5' cGMP to polymerize. The observation that numerous amorphous and crystalline SiO2 forms are compatible with the oligomerization chemistry suggests that the process could commonly occur in a wide range of primordial environments allowing for crystallization of the cyclic monomers from a dropping solution.

Návaznosti

GA19-03442S, projekt VaV

Název: Geny pro ribozomální RNA - cestovatelé v čase a genomech

Investor: Grantová agentura ČR, Geny pro ribozomální RNA - cestovatelé v čase a genomech

90127, velká výzkumná infrastruktura

Název: CIISB II

Citovat

ŠPONEROVÁ, Judit, Jiří ŠPONER, Jakub VÝRAVSKÝ, Ondrej ŠEDO, Zbyněk ZDRÁHAL, Giovanna COSTANZO, Ernesto DI MAURO, Sreekar WUNNAVA, Dieter BRAUN, Roman MATYÁŠEK a Aleš KOVAŘÍK. Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces. ChemSystemsChem. Wiley, 2021, roč. 3, č. 6, s. "e2100017", 8 s. ISSN 2570-4206. Dostupné z: https://dx.doi.org/10.1002/syst.202100017.

@article{1824781,
   author = {Šponerová, Judit and Šponer, Jiří and Výravský, Jakub and Šedo, Ondrej and Zdráhal, Zbyněk and Costanzo, Giovanna and di Mauro, Ernesto and Wunnava, Sreekar and Braun, Dieter and Matyášek, Roman and Kovařík, Aleš},
   article_number = {6},
   doi = {http://dx.doi.org/10.1002/syst.202100017},
   keywords = {minerals; nucleotides; oligomerization; oligonucleotides; self-assembly},
   language = {eng},
   issn = {2570-4206},
   journal = {ChemSystemsChem},
   title = {Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces},
   url = {https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/syst.202100017},
   volume = {3},
   year = {2021}
}

TY  - JOUR
ID  - 1824781
AU  - Šponerová, Judit - Šponer, Jiří - Výravský, Jakub - Šedo, Ondrej - Zdráhal, Zbyněk - Costanzo, Giovanna - di Mauro, Ernesto - Wunnava, Sreekar - Braun, Dieter - Matyášek, Roman - Kovařík, Aleš
PY  - 2021
TI  - Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces
JF  - ChemSystemsChem
VL  - 3
IS  - 6
SP  - "e2100017"
EP  - "e2100017"
PB  - Wiley
SN  - 25704206
KW  - minerals
KW  - nucleotides
KW  - oligomerization
KW  - oligonucleotides
KW  - self-assembly
UR  - https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/syst.202100017
N2  - Previous studies on the polymerization of 3',5' cyclic guanosine monophosphate (cGMP) demonstrated the potential of the compound in the abiotic generation of the first oligonucleotide sequences on the early Earth. These experiments were conducted under idealized laboratory conditions, which logically raises the question whether the same chemistry could take place in the harsh environment present on our planet in its earliest days. In the current study, we focus on the mineralogical context of this chemistry and show that numerous, but not all, common minerals assumed to be present on the early Earth could host the polymerization of H-form 3',5' cGMP. In particular, we have found that quartz varieties are especially suitable for this purpose, similar to andalusite, amphibole or micas. On the contrary, olivine, calcite, and serpentine-group minerals interfere with the studied polymerization chemistry. Our results show that crystallization on mineral surfaces, which is mainly a diffusion controlled process, determines the ability of 3',5' cGMP to polymerize. The observation that numerous amorphous and crystalline SiO2 forms are compatible with the oligomerization chemistry suggests that the process could commonly occur in a wide range of primordial environments allowing for crystallization of the cyclic monomers from a dropping solution.
ER  -

ŠPONEROVÁ, Judit, Jiří ŠPONER, Jakub VÝRAVSKÝ, Ondrej ŠEDO, Zbyněk ZDRÁHAL, Giovanna COSTANZO, Ernesto DI MAURO, Sreekar WUNNAVA, Dieter BRAUN, Roman MATYÁŠEK a Aleš KOVAŘÍK. Nonenzymatic, Template-Free Polymerization of 3',5' Cyclic Guanosine Monophosphate on Mineral Surfaces. \textit{ChemSystemsChem}. Wiley, 2021, roč.~3, č.~6, s.~''e2100017'', 8 s. ISSN~2570-4206. Dostupné z: https://dx.doi.org/10.1002/syst.202100017.

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