Multiphase CTA-derived tissue maps aid in detection of medium
vessel occlusions

J 2022

Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions

MCDONOUGH, R. V., W. QIU, J. M. OSPEL, B. K. MENON, Petra CIMFLOVÁ et. al.

Základní údaje

Originální název

Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions

Autoři

MCDONOUGH, R. V., W. QIU, J. M. OSPEL, B. K. MENON, Petra CIMFLOVÁ (203 Česká republika, domácí) a M. GOYAL (garant)

Vydání

NEURORADIOLOGY, NEW YORK, SPRINGER, 2022, 0028-3940

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30224 Radiology, nuclear medicine and medical imaging

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.800

Kód RIV

RIV/00216224:14110/22:00125371

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s00234-021-02830-8

UT WoS

000708810800003

Klíčová slova anglicky

Acute ischemic stroke; Endovascular treatment; Medium vessel occlusions; Multiphase computed tomography; Treatment selection

Štítky

14110119, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 28. 4. 2022 11:05, Mgr. Tereza Miškechová

Anotace

V originále

Purpose Medium vessel occlusions (MeVOs) can be challenging to detect on imaging. Multiphase computed tomography angiography (mCTA) has been shown to improve large vessel occlusion (LVO) detection and endovascular treatment (EVT) selection. The aims of this study were to determine if mCTA-derived tissue maps can (1) accurately detect MeVOs and (2) predict infarction on 24-h follow-up imaging with comparable accuracy to CT perfusion (CTP). Methods Two readers assessed mCTA tissue maps of 116 ischemic stroke patients (58 MeVOs, 58 non-MeVOs) and determined by consensus: (1) MeVO (yes/no) and (2) occlusion site, blinded to clinical or imaging data. Sensitivity, specificity, and area under the curve (AUC) for MeVO detection were estimated in comparison to reference standards of (1) expert readings of baseline mCTA and (2) CTP maps. Volumetric and spatial agreement between mCTA- and CTP-predicted infarcts was assessed using concordance/intraclass correlation and Dice coefficients. Interrater agreement for MeVO detection on mCTA tissue maps was estimated with Cohen's kappa. Results MeVO detection from mCTA-derived tissue maps had a sensitivity of 91% (95% CI: 80-97), specificity of 82% (95% CI: 70-90), and AUC of 0.87 (95% CI: 0.80-0.93) compared to expert reads of baseline mCTA. Interrater reliability was good (0.72, 95% CI: 0.60-0.85). Compared to CTP maps, sensitivity was 87% (95% CI: 75-95), specificity was 78% (95%CI: 65-88), and AUC was 0.83 (95% CI: 0.76-0.90). The mean difference between mCTA- and CTP-predicted final infarct volume was 4.8 mL (limits of agreement: - 58.5 to 68.1) with a Dice coefficient of 33.5%. Conclusion mCTA tissue maps can be used to reliably detect MeVO stroke and predict tissue fate.

Citovat

MCDONOUGH, R. V., W. QIU, J. M. OSPEL, B. K. MENON, Petra CIMFLOVÁ a M. GOYAL. Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions. NEURORADIOLOGY. NEW YORK: SPRINGER, 2022, roč. 64, č. 5, s. 887-896. ISSN 0028-3940. Dostupné z: https://dx.doi.org/10.1007/s00234-021-02830-8.

@article{1834327,
   author = {McDonough, R. V. and Qiu, W. and Ospel, J. M. and Menon, B. K. and Cimflová, Petra and Goyal, M.},
   article_location = {NEW YORK},
   article_number = {5},
   doi = {http://dx.doi.org/10.1007/s00234-021-02830-8},
   keywords = {Acute ischemic stroke; Endovascular treatment; Medium vessel occlusions; Multiphase computed tomography; Treatment selection},
   language = {eng},
   issn = {0028-3940},
   journal = {NEURORADIOLOGY},
   title = {Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions},
   url = {https://link.springer.com/article/10.1007/s00234-021-02830-8},
   volume = {64},
   year = {2022}
}

TY  - JOUR
ID  - 1834327
AU  - McDonough, R. V. - Qiu, W. - Ospel, J. M. - Menon, B. K. - Cimflová, Petra - Goyal, M.
PY  - 2022
TI  - Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions
JF  - NEURORADIOLOGY
VL  - 64
IS  - 5
SP  - 887-896
EP  - 887-896
PB  - SPRINGER
SN  - 00283940
KW  - Acute ischemic stroke
KW  - Endovascular treatment
KW  - Medium vessel occlusions
KW  - Multiphase computed tomography
KW  - Treatment selection
UR  - https://link.springer.com/article/10.1007/s00234-021-02830-8
N2  - Purpose Medium vessel occlusions (MeVOs) can be challenging to detect on imaging. Multiphase computed tomography angiography (mCTA) has been shown to improve large vessel occlusion (LVO) detection and endovascular treatment (EVT) selection. The aims of this study were to determine if mCTA-derived tissue maps can (1) accurately detect MeVOs and (2) predict infarction on 24-h follow-up imaging with comparable accuracy to CT perfusion (CTP). Methods Two readers assessed mCTA tissue maps of 116 ischemic stroke patients (58 MeVOs, 58 non-MeVOs) and determined by consensus: (1) MeVO (yes/no) and (2) occlusion site, blinded to clinical or imaging data. Sensitivity, specificity, and area under the curve (AUC) for MeVO detection were estimated in comparison to reference standards of (1) expert readings of baseline mCTA and (2) CTP maps. Volumetric and spatial agreement between mCTA- and CTP-predicted infarcts was assessed using concordance/intraclass correlation and Dice coefficients. Interrater agreement for MeVO detection on mCTA tissue maps was estimated with Cohen's kappa. Results MeVO detection from mCTA-derived tissue maps had a sensitivity of 91% (95% CI: 80-97), specificity of 82% (95% CI: 70-90), and AUC of 0.87 (95% CI: 0.80-0.93) compared to expert reads of baseline mCTA. Interrater reliability was good (0.72, 95% CI: 0.60-0.85). Compared to CTP maps, sensitivity was 87% (95% CI: 75-95), specificity was 78% (95%CI: 65-88), and AUC was 0.83 (95% CI: 0.76-0.90). The mean difference between mCTA- and CTP-predicted final infarct volume was 4.8 mL (limits of agreement: - 58.5 to 68.1) with a Dice coefficient of 33.5%. Conclusion mCTA tissue maps can be used to reliably detect MeVO stroke and predict tissue fate.
ER  -

MCDONOUGH, R. V., W. QIU, J. M. OSPEL, B. K. MENON, Petra CIMFLOVÁ a M. GOYAL. Multiphase CTA-derived tissue maps aid in detection of medium vessel occlusions. \textit{NEURORADIOLOGY}. NEW YORK: SPRINGER, 2022, roč.~64, č.~5, s.~887-896. ISSN~0028-3940. Dostupné z: https://dx.doi.org/10.1007/s00234-021-02830-8.

Podrobný výpis o publikaci