Aggressive systemic mastocytosis with diffuse bone marrow (18)
F-FDG uptake

J 2022

Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK, Petr SZTURZ et. al.

Základní údaje

Originální název

Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake

Autoři

KOUKALOVÁ, Renata (203 Česká republika, domácí), Jiří VAŠINA (203 Česká republika, domácí), Jiří ŠTIKA (203 Česká republika, domácí), Michael DOUBEK (203 Česká republika, domácí) a Petr SZTURZ (203 Česká republika, garant)

Vydání

Nuklearmedizin-Nuclear Medicine, Stuttgart, Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, 0029-5566

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30224 Radiology, nuclear medicine and medical imaging

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.500

Kód RIV

RIV/00216224:14110/22:00125372

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1055/a-1650-9704

UT WoS

000715521100001

Klíčová slova anglicky

mastocytosis; positron emission tomography; computed tomography; KIT D816V mutation; osteopenia; osteosclerosis

Štítky

14110212, 14110811, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 19. 2. 2024 11:10, Mgr. Tereza Miškechová

Anotace

V originále

Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis.

Citovat

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK a Petr SZTURZ. Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake. Nuklearmedizin-Nuclear Medicine. Stuttgart: Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, roč. 61, č. 01, s. 58-61. ISSN 0029-5566. Dostupné z: https://dx.doi.org/10.1055/a-1650-9704.

@article{1834338,
   author = {Koukalová, Renata and Vašina, Jiří and Štika, Jiří and Doubek, Michael and Szturz, Petr},
   article_location = {Stuttgart},
   article_number = {01},
   doi = {http://dx.doi.org/10.1055/a-1650-9704},
   keywords = {mastocytosis; positron emission tomography; computed tomography; KIT D816V mutation; osteopenia; osteosclerosis},
   language = {eng},
   issn = {0029-5566},
   journal = {Nuklearmedizin-Nuclear Medicine},
   title = {Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake},
   url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704},
   volume = {61},
   year = {2022}
}

TY  - JOUR
ID  - 1834338
AU  - Koukalová, Renata - Vašina, Jiří - Štika, Jiří - Doubek, Michael - Szturz, Petr
PY  - 2022
TI  - Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake
JF  - Nuklearmedizin-Nuclear Medicine
VL  - 61
IS  - 01
SP  - 58-61
EP  - 58-61
PB  - Schattauer GmbH-Verlag Medizin Naturwissenschaften
SN  - 00295566
KW  - mastocytosis
KW  - positron emission tomography
KW  - computed tomography
KW  - KIT D816V mutation
KW  - osteopenia
KW  - osteosclerosis
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704
N2  - Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis.
ER  -

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK a Petr SZTURZ. Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake. \textit{Nuklearmedizin-Nuclear Medicine}. Stuttgart: Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, roč.~61, č.~01, s.~58-61. ISSN~0029-5566. Dostupné z: https://dx.doi.org/10.1055/a-1650-9704.

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