UK Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) on behalf of the Medicines and Healthcare products Regulatory Agency (MHRA) Plastic, Reconstructive and Aesthetic Surgery Expert Advisory Group (PRASEAG)

TURTON, P,; D, EL-SHARKAWI; I, LYBURN; B, SHARMA; P, MAHALINGAM; Suzanne Dawn TURNER; F. MACNEILL; L. JOHNSON; S. HAMILTON; C. BURTON a N. MERCER. UK Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) on behalf of the Medicines and Healthcare products Regulatory Agency (MHRA) Plastic, Reconstructive and Aesthetic Surgery Expert Advisory Group (PRASEAG). JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY. OXFORD: ELSEVIER SCI LTD, 2021, roč. 74, č. 1, s. 13-29. ISSN 1748-6815. Dostupné z: https://doi.org/10.1016/j.bjps.2020.10.064.

Základní údaje

Originální název

UK Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) on behalf of the Medicines and Healthcare products Regulatory Agency (MHRA) Plastic, Reconstructive and Aesthetic Surgery Expert Advisory Group (PRASEAG)

Autoři

TURTON, P,; D, EL-SHARKAWI; I, LYBURN; B, SHARMA; P, MAHALINGAM; Suzanne Dawn TURNER; F. MACNEILL; L. JOHNSON; S. HAMILTON; C. BURTON a N. MERCER

Vydání

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, OXFORD, ELSEVIER SCI LTD, 2021, 1748-6815

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Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30212 Surgery

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.022

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14740/21:00124191

Organizační jednotka

Středoevropský technologický institut

DOI

https://doi.org/10.1016/j.bjps.2020.10.064

UT WoS

000668590800003

EID Scopus

2-s2.0-85099622568

Klíčová slova anglicky

BIA-ALCL; reconstructive breast surgery; lymphoma; breast implants; treatment guidelines

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

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Anotace

V originále

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T cell Non-Hodgkin Lymphoma (NHL) associated with breast implants. Raising awareness of the possibility of BIA-ALCL in anyone with breast implants and new breast symptoms is crucial to early diagnosis. The tumour begins on the inner aspect of the peri-implant capsule causing an effusion, or less commonly a tissue mass to form within the capsule, which may spread locally or to more distant sites in the body. Diagnosis is usually made by cytological, immunohistochemical and immunophenotypic evaluation of the peri-implant fluid: pleomorphic lymphocytes are characteristically anaplastic lymphoma kinase (ALK) negative and strongly positive for CD30. BIA-ALCL is indolent in most patients but can progress rapidly. Surgical removal of the implant with the intact surrounding capsule (total en-bloc capsulectomy) is usually curative. Late diagnosis may require more radical surgery and systemic therapies and although these are usually successful, poor outcomes and deaths have been reported. By adopting a structured approach, as suggested in these guidelines, early diagnosis and successful treatment will minimize the need for systemic treatments, reduce morbidity and the risk of poor outcomes. These guide-lines provide an evidence-based and systematic framework for the assessment and treatment of patients with suspected or proven BIA-ALCL and are aimed at all clinicians involved in the care of people with breast implants. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of Elsevier Ltd, British Association of Surgical Oncology & European Society of Surgical Oncology; published by Wiley on behalf of John Wiley and Sons Limited; and published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons. All rights reserved.