Biological activity of Cannabis compounds: a modern approach to
the therapy of multiple diseases

J 2021

Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases

HELCMAN, Martin a Karel ŠMEJKAL

Základní údaje

Originální název

Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases

Autoři

HELCMAN, Martin (703 Slovensko, garant, domácí) a Karel ŠMEJKAL (203 Česká republika, domácí)

Vydání

Phytochemistry reviews, Dordrecht, Springer, 2021, 1568-7767

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.741

Kód RIV

RIV/00216224:14160/21:00124272

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.1007/s11101-021-09777-x

UT WoS

000708808100002

Klíčová slova anglicky

Cannabis; Cannabinoid; Terpenoid; Therapy

Štítky

rivok, ÚPL

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 23. 2. 2022 16:15, JUDr. Sabina Krejčiříková

Anotace

V originále

Cannabis spp. are some of the most controversial medicinal plants in the world. They contain great amounts of biologically active secondary metabolites, including the typical phenolic compounds called cannabinoids. Because of their low toxicity and complex biological activities, cannabinoids can be useful in the therapy of various diseases, but adverse psychological effects (of Delta(9)-THC in particular) raise concerns. This review summarizes the current knowledge of selected active C. indica compounds and their therapeutic potential. We summarize the main compounds contained in cannabis, the mechanisms of their effects, and their potential therapeutic applications. Further, we mention some of the clinical tests used to evaluate the efficacy of cannabinoids in therapy.

Návaznosti

MUNI/A/1688/2020, interní kód MU

Název: Izolace sekundárních metabolitů s potenciální biologickou aktivitou z rostlinných zdrojů (Akronym: Izolace sekundárních metabolitů)

Investor: Masarykova univerzita, Izolace sekundárních metabolitů s potenciální biologickou aktivitou z rostlinných zdrojů

Citovat

HELCMAN, Martin a Karel ŠMEJKAL. Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases. Phytochemistry reviews. Dordrecht: Springer, 2021, Neuveden., October, s. 1-42. ISSN 1568-7767. Dostupné z: https://dx.doi.org/10.1007/s11101-021-09777-x.

@article{1836638,
   author = {Helcman, Martin and Šmejkal, Karel},
   article_location = {Dordrecht},
   article_number = {October},
   doi = {http://dx.doi.org/10.1007/s11101-021-09777-x},
   keywords = {Cannabis; Cannabinoid; Terpenoid; Therapy},
   language = {eng},
   issn = {1568-7767},
   journal = {Phytochemistry reviews},
   title = {Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases},
   url = {https://link.springer.com/article/10.1007/s11101-021-09777-x},
   volume = {Neuveden.},
   year = {2021}
}

TY  - JOUR
ID  - 1836638
AU  - Helcman, Martin - Šmejkal, Karel
PY  - 2021
TI  - Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases
JF  - Phytochemistry reviews
VL  - Neuveden.
IS  - October
SP  - 1-42
EP  - 1-42
PB  - Springer
SN  - 15687767
KW  - Cannabis
KW  - Cannabinoid
KW  - Terpenoid
KW  - Therapy
UR  - https://link.springer.com/article/10.1007/s11101-021-09777-x
N2  - Cannabis spp. are some of the most controversial medicinal plants in the world. They contain great amounts of biologically active secondary metabolites, including the typical phenolic compounds called cannabinoids. Because of their low toxicity and complex biological activities, cannabinoids can be useful in the therapy of various diseases, but adverse psychological effects (of Delta(9)-THC in particular) raise concerns. This review summarizes the current knowledge of selected active C. indica compounds and their therapeutic potential. We summarize the main compounds contained in cannabis, the mechanisms of their effects, and their potential therapeutic applications. Further, we mention some of the clinical tests used to evaluate the efficacy of cannabinoids in therapy.
ER  -

HELCMAN, Martin a Karel ŠMEJKAL. Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases. \textit{Phytochemistry reviews}. Dordrecht: Springer, 2021, Neuveden., October, s.~1-42. ISSN~1568-7767. Dostupné z: https://dx.doi.org/10.1007/s11101-021-09777-x.

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