SOPOUŠEK, Jakub, Josef HUMLÍČEK, Antonín HLAVÁČEK, Veronika HORÁČKOVÁ, Petr SKLÁDAL and Karel LACINA. Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing. Electrochimica Acta. OXFORD: Elsevier, 2021, vol. 368, FEB, p. 137607-137615. ISSN 0013-4686. doi:10.1016/j.electacta.2020.137607.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing
Authors SOPOUŠEK, Jakub (203 Czech Republic), Josef HUMLÍČEK (203 Czech Republic, belonging to the institution), Antonín HLAVÁČEK (203 Czech Republic), Veronika HORÁČKOVÁ (203 Czech Republic), Petr SKLÁDAL (203 Czech Republic, belonging to the institution) and Karel LACINA (203 Czech Republic, guarantor, belonging to the institution).
Edition Electrochimica Acta, OXFORD, Elsevier, 2021, 0013-4686.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10405 Electrochemistry
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 7.336
RIV identification code RIV/00216224:14740/21:00119678
Organization unit Central European Institute of Technology
UT WoS 000609069000013
Keywords in English Nanopores; Nanoparticles; Multilayers; Thin film interference; Electrochemical impedance; Biosensing
Tags CF NANO, rivok
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 5. 5. 2022 15:19.
Solid-state nanopores with diameter in units of nanometer can be formed by assembling spherical nanoparticles in a dense arrangement. In the current work, the properties of multi-layered highly ordered assemblies of polystyrene nanoparticles were studied, and their feasibility for electrochemical biosensing was probed. These thick matrices were built using a step-by-step deposition technique. Each individual layer of NPs exhibited distinct color which was caused by the thin film interference effect (a color of specific wavelength was characteristic for matrix of specific thickness). The electrochemical characteristics of matrices were investigated with impedance spectroscopy. The impedance spectra of multi-layered matrices exhibited formation of an additional semicircle (RC component additional to the one in a common Randles equivalent circuit). Further, model biosensing based on nanopore blocking was performed using human serum albumin as an antigen and the corresponding monoclonal antibody as an analyte (serology format). Resulting data disfavored the direct employment of the multi-layered matrices for biosensing purposes as the efficiency decreased with increasing thickness of matrices. However, the data revealed highly valuable information about the diffusion and redox processes in the thick nanoporous matrices. (C) 2020 Elsevier Ltd. All rights reserved.
GJ19-16273Y, research and development projectName: ROS-indukované uvolňování léčiv založené na interakcích ferocenylboronátů
Investor: Czech Science Foundation, ROS-Induced Drug Release Based on Interactions of Ferrocenylboronates
LM2018127, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 23. 9. 2023 12:41