Neglected Facts on Mycobacterium Avium Subspecies
Paratuberculosis and Type 1 Diabetes

J 2022

Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes

OŽANA, Veronika, K. HRUŠKA a L.A. SECHI

Základní údaje

Originální název

Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes

Autoři

OŽANA, Veronika (203 Česká republika, domácí), K. HRUŠKA (garant) a L.A. SECHI

Vydání

International Journal of Molecular Sciences, Basel, MDPI, 2022, 1422-0067

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.600

Kód RIV

RIV/00216224:14160/22:00125760

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.3390/ijms23073657

UT WoS

000781092200001

Klíčová slova anglicky

chronic inflammatory diseases; autoimmune diseases; T1D; nontuberculous mycobacteria; civilization diseases; civilization factors; global health problem; Mycobacterium avium subspecies paratuberculosis

Štítky

rivok, ÚFTo

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 4. 5. 2022 10:02, JUDr. Sabina Krejčiříková

Anotace

V originále

Civilization factors are responsible for the increasing of human exposure to mycobacteria from environment, water, and food during the last few decades. Urbanization, lifestyle changes and new technologies in the animal and plant industry are involved in frequent contact of people with mycobacteria. Type 1 diabetes is a multifactorial polygenic disease; its origin is conditioned by the mutual interaction of genetic and other factors. The environmental factors and certain pathogenetic pathways are shared by some immune mediated chronic inflammatory and autoimmune diseases, which are associated with triggers originating mainly from Mycobacterium avium subspecies paratuberculosis, an intestinal pathogen which persists in the environment. Type 1 diabetes and some other chronic inflammatory diseases thus pose the global health problem which could be mitigated by measures aimed to decrease the human exposure to this neglected zoonotic mycobacterium.

Citovat

OŽANA, Veronika, K. HRUŠKA a L.A. SECHI. Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes. International Journal of Molecular Sciences. Basel: MDPI, 2022, roč. 23, č. 7, s. 1-13. ISSN 1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms23073657.

@article{1850959,
   author = {Ožana, Veronika and Hruška, K. and Sechi, L.A.},
   article_location = {Basel},
   article_number = {7},
   doi = {http://dx.doi.org/10.3390/ijms23073657},
   keywords = {chronic inflammatory diseases; autoimmune diseases; T1D; nontuberculous mycobacteria; civilization diseases; civilization factors; global health problem; Mycobacterium avium subspecies paratuberculosis},
   language = {eng},
   issn = {1422-0067},
   journal = {International Journal of Molecular Sciences},
   title = {Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes},
   url = {https://www.mdpi.com/1422-0067/23/7/3657/htm},
   volume = {23},
   year = {2022}
}

TY  - JOUR
ID  - 1850959
AU  - Ožana, Veronika - Hruška, K. - Sechi, L.A.
PY  - 2022
TI  - Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes
JF  - International Journal of Molecular Sciences
VL  - 23
IS  - 7
SP  - 1-13
EP  - 1-13
PB  - MDPI
SN  - 14220067
KW  - chronic inflammatory diseases
KW  - autoimmune diseases
KW  - T1D
KW  - nontuberculous mycobacteria
KW  - civilization diseases
KW  - civilization factors
KW  - global health problem
KW  - Mycobacterium avium subspecies paratuberculosis
UR  - https://www.mdpi.com/1422-0067/23/7/3657/htm
N2  - Civilization factors are responsible for the increasing of human exposure to mycobacteria from environment, water, and food during the last few decades. Urbanization, lifestyle changes and new technologies in the animal and plant industry are involved in frequent contact of people with mycobacteria. Type 1 diabetes is a multifactorial polygenic disease; its origin is conditioned by the mutual interaction of genetic and other factors. The environmental factors and certain pathogenetic pathways are shared by some immune mediated chronic inflammatory and autoimmune diseases, which are associated with triggers originating mainly from Mycobacterium avium subspecies paratuberculosis, an intestinal pathogen which persists in the environment. Type 1 diabetes and some other chronic inflammatory diseases thus pose the global health problem which could be mitigated by measures aimed to decrease the human exposure to this neglected zoonotic mycobacterium.
ER  -

OŽANA, Veronika, K. HRUŠKA a L.A. SECHI. Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes. \textit{International Journal of Molecular Sciences}. Basel: MDPI, 2022, roč.~23, č.~7, s.~1-13. ISSN~1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms23073657.

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