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@inbook{1852912,
author = {Skládal, Petr},
booktitle = {Portable Biosensors and Point-of-Care Systems},
doi = {http://dx.doi.org/10.1049/PBHE003E_ch11},
editor = {Kintzios, Spyridon E},
keywords = {immunochemical devices; point-of-care; viruses; bacteria; ELISA; antibodies; biowarfare detection; bioagents; immunosensors; polymerase chain reaction; affinity based recognition systems},
howpublished = {tištěná verze "print"},
language = {eng},
isbn = {978-1-84919-962-9},
pages = {209-230},
publisher = {Institution of Engineering and Technology},
title = {POC in biowarfare detection and defence applications: an update},
url = {https://doi.org/10.1049/PBHE003E_ch11},
year = {2017}
}
TY - CHAP
ID - 1852912
AU - Skládal, Petr
PY - 2017
TI - POC in biowarfare detection and defence applications: an update
PB - Institution of Engineering and Technology
SN - 9781849199629
KW - immunochemical devices
KW - point-of-care
KW - viruses
KW - bacteria
KW - ELISA
KW - antibodies
KW - biowarfare detection
KW - bioagents
KW - immunosensors
KW - polymerase chain reaction
KW - affinity based recognition systems
UR - https://doi.org/10.1049/PBHE003E_ch11
N2 - For bacteria and viruses as bioagents, various types of immunochemical devices are preferred for the early response and good sensitivity; the capability of continuous monitoring is also a quite attractive advantage. The detection occurs on the phenotype level, and no extraction of the genetic material from the bioagent is required, which is the necessary case for methods based on PCR and general detection of specific nucleic acid sequences. ELISA as a classic immunoanalytical format inspired various types of immunosensors. Here, the optical [10] and electrochemical [11] immunosensors will be addressed as the approach combining high sensitivity, simple construction and portability of the sensing part with the excellent specificity of antibodies and other affinity-based recognition systems.
ER -
SKLÁDAL, Petr. POC in biowarfare detection and defence applications: an update. In Kintzios, Spyridon E. \textit{Portable Biosensors and Point-of-Care Systems}. Institution of Engineering and Technology, 2017, s.~209-230. ISBN~978-1-84919-962-9. Dostupné z: https://dx.doi.org/10.1049/PBHE003E\_{}ch11.
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