2016
A novel method for left anterior coronary artery flow velocity assessment by transthoracic echocardiography at the peak of a supine bicycle test
ZAGATINA, Angela; Nadezhda ZHURAVSKAYA; Emmanuel EGOM; Gabriela KOVACOVA; Peter KRUŽLIAK et al.Základní údaje
Originální název
A novel method for left anterior coronary artery flow velocity assessment by transthoracic echocardiography at the peak of a supine bicycle test
Autoři
ZAGATINA, Angela; Nadezhda ZHURAVSKAYA; Emmanuel EGOM; Gabriela KOVACOVA a Peter KRUŽLIAK
Vydání
Acta Radiologica, London, SAGE Publications Inc. 2016, 0284-1851
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30224 Radiology, nuclear medicine and medical imaging
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.011
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/16:00124648
Organizační jednotka
Lékařská fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
Coronary flow reserve; visualization of coronary artery; exercise echo; LAD flow; coronary flow velocity
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 20. 5. 2022 10:55, Mgr. Tereza Miškechová
Anotace
V originále
Background Assessment of coronary flow is only performed during pharmacological tests. Supine bicycle tests permit the visualization of coronary flow assessments during exercise. Purpose To assess the parameters of coronary flow in the left anterior descending artery (LAD) during exercise, which could be a sign of significant LAD narrowing. Material and Methods A total of 253 patients were enrolled: Group 1, 186 non-selective participants before undergoing a coronary angiography; and Group 2, 67 controls without coronary artery disease (CAD). All the patients performed a supine bicycle echocardiography test. Coronary flow velocities and coronary flow velocity reserve (CFVR) were measured at the mid-segment of the LAD during exercise. Patients in Group 1 underwent a coronary angiography. Results In comparison with participants without significant LAD stenosis, patients with LAD lesions had a lower V (1621 vs. 27 +/- 20cm/s, P<0.04) and a lower CFVR (1.5 +/- 0.8 vs. 2.0 +/- 0.6, P<0.004). In comparison with patients without significant proximal LAD stenosis, the patients with proximal LAD lesions had a lower flow velocity at the peak of exercise (49 +/- 32 vs. 61 +/- 19cm/s, P<0.02), a lower V (13 +/- 19 vs. 26 +/- 22cm/s, P<0.004), and a lower CFVR (1.4 +/- 0.6 vs. 1.9 +/- 0.7, P<0.0001). In comparison with the control group, the patients with LAD stenosis had a lower flow velocity at the peak of exercise, a lower V, and a lower CFVR. Conclusion Non-invasive CFVR measurement in the LAD could provide valuable additional information to a conventional echocardiography exercise test. In routine clinical practice, CFVR is sufficient for a diagnosis of severe stenosis.