Respiratory induced heart rate variability during slow
mechanical ventilation Marker to exclude brain death patients

J 2017

Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients

JURAK, Pavel; Josef HALAMEK; Vlastimil VONDRA; Peter KRUZLIAK; Vladimír ŠRÁMEK et al.

Základní údaje

Originální název

Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients

Autoři

JURAK, Pavel; Josef HALAMEK; Vlastimil VONDRA; Peter KRUZLIAK; Vladimír ŠRÁMEK; Ivan ČUNDRLE; Pavel LEINVEBER; Mariusz ADAMEK a Václav ZVONÍČEK

Vydání

Wiener klinische Wochenschrift, Vídeň, SPRINGER WIEN, 2017, 0043-5325

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Rakousko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.003

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/17:00124678

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Critical illness; Sedation; Brain death; Respiratory rate variability; Heart rate variability; Mechanical ventilation

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 5. 2022 11:09, Mgr. Tereza Miškechová

Anotace

V originále

Respiratory induced heart rate variability (rHRV) was analysed in mechanically ventilated patients during two levels of sedation and brain death. Our aim was to determine whether rHRV can distinguish between different levels of sedation and especially between brain death and sedated patients. In this study 30 critically ill and 23 brain death patients were included and four respiratory rates of 15, 12, 8 and 6 breaths per minute, each lasting 5 min were used. Two sedation levels, basal and deep, were performed in the critically ill patients. Heart rate and blood pressure changes induced by ventilation were subsequently detected and analysed. Significant differences were found in rHRV and rHRV adjusted for tidal volume (rHRV/VT) between critically ill and brain death patients during slow breathing at 6 or 8 breaths per minute. The rHRV at 6 breaths per minute was below 15 ms in all brain death subjects except one. The rHRV/VT was lower than 25 ms/l at both 6 and 8 breaths per minute in all brain death patients and simultaneously at 75% of non-brain death patients was higher (specificity 1, sensitivity 0.24). Differences in rHRV and rHRV/VTs between basal and deep sedation were not significant. The main clinical benefit of the study is the finding that rHRV and rHRV/VT during 6 and 8 breaths per minute can differentiate between critically ill and brain death patients. An rHRV/VT exceeding 25 ms/l reliably excludes brain death.

Návaznosti

GAP103/11/0933, projekt VaV

Název: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Investor: Grantová agentura ČR, Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Citovat

JURAK, Pavel; Josef HALAMEK; Vlastimil VONDRA; Peter KRUZLIAK; Vladimír ŠRÁMEK; Ivan ČUNDRLE; Pavel LEINVEBER; Mariusz ADAMEK a Václav ZVONÍČEK. Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients. Wiener klinische Wochenschrift. Vídeň: SPRINGER WIEN, 2017, roč. 129, 7-8, s. 251-258. ISSN 0043-5325. Dostupné z: https://doi.org/10.1007/s00508-017-1176-0.

@article{1854533,
   author = {Jurak, Pavel and Halamek, Josef and Vondra, Vlastimil and Kruzliak, Peter and Šrámek, Vladimír and Čundrle, Ivan and Leinveber, Pavel and Adamek, Mariusz and Zvoníček, Václav},
   article_location = {Vídeň},
   article_number = {7-8},
   doi = {https://doi.org/10.1007/s00508-017-1176-0},
   keywords = {Critical illness; Sedation; Brain death; Respiratory rate variability; Heart rate variability; Mechanical ventilation},
   language = {eng},
   issn = {0043-5325},
   journal = {Wiener klinische Wochenschrift},
   title = {Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients},
   url = {https://link.springer.com/article/10.1007/s00508-017-1176-0},
   volume = {129},
   year = {2017}
}

TY  - JOUR
ID  - 1854533
AU  - Jurak, Pavel - Halamek, Josef - Vondra, Vlastimil - Kruzliak, Peter - Šrámek, Vladimír - Čundrle, Ivan - Leinveber, Pavel - Adamek, Mariusz - Zvoníček, Václav
PY  - 2017
TI  - Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients
JF  - Wiener klinische Wochenschrift
VL  - 129
IS  - 7-8
SP  - 251-258
EP  - 251-258
PB  - SPRINGER WIEN
SN  - 00435325
KW  - Critical illness
KW  - Sedation
KW  - Brain death
KW  - Respiratory rate variability
KW  - Heart rate variability
KW  - Mechanical ventilation
UR  - https://link.springer.com/article/10.1007/s00508-017-1176-0
N2  - Respiratory induced heart rate variability (rHRV) was analysed in mechanically ventilated patients during two levels of sedation and brain death. Our aim was to determine whether rHRV can distinguish between different levels of sedation and especially between brain death and sedated patients. In this study 30 critically ill and 23 brain death patients were included and four respiratory rates of 15, 12, 8 and 6 breaths per minute, each lasting 5 min were used. Two sedation levels, basal and deep, were performed in the critically ill patients. Heart rate and blood pressure changes induced by ventilation were subsequently detected and analysed. Significant differences were found in rHRV and rHRV adjusted for tidal volume (rHRV/VT) between critically ill and brain death patients during slow breathing at 6 or 8 breaths per minute. The rHRV at 6 breaths per minute was below 15 ms in all brain death subjects except one. The rHRV/VT was lower than 25 ms/l at both 6 and 8 breaths per minute in all brain death patients and simultaneously at 75% of non-brain death patients was higher (specificity 1, sensitivity 0.24). Differences in rHRV and rHRV/VTs between basal and deep sedation were not significant. The main clinical benefit of the study is the finding that rHRV and rHRV/VT during 6 and 8 breaths per minute can differentiate between critically ill and brain death patients. An rHRV/VT exceeding 25 ms/l reliably excludes brain death.
ER  -

JURAK, Pavel; Josef HALAMEK; Vlastimil VONDRA; Peter KRUZLIAK; Vladimír ŠRÁMEK; Ivan ČUNDRLE; Pavel LEINVEBER; Mariusz ADAMEK a Václav ZVONÍČEK. Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients. \textit{Wiener klinische Wochenschrift}. Vídeň: SPRINGER WIEN, 2017, roč.~129, 7-8, s.~251-258. ISSN~0043-5325. Dostupné z: https://doi.org/10.1007/s00508-017-1176-0.

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