Immediate breast reconstruction in patients with BRCA mutation
and breast cancer - our approach.

a 2022

Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach.

VENTRUBA, Tomáš; Luboš MINÁŘ; Dagmar BRANČÍKOVÁ; Markéta PROTIVÁNKOVÁ; Pavel VENTRUBA et al.

Základní údaje

Originální název

Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach.

Autoři

VENTRUBA, Tomáš; Luboš MINÁŘ; Dagmar BRANČÍKOVÁ; Markéta PROTIVÁNKOVÁ a Pavel VENTRUBA

Vydání

ESMO Breast Cancer Congress, 2022 (3-5 May), Berlin, Germany. 2022

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.annonc/2022.03.148

Klíčová slova anglicky

breast-conserving surgery; BRCA mutation; immediate reconstruction; recurrence risk

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 4. 2023 12:11, Mgr. Tereza Miškechová

Anotace

V originále

Analysis of our approach to immediate breast reconstruction after mastectomy in women with breast cancer and / or BRCA mutations. Methods: We use the possibility of immediate breast reconstruction at the same time with subcutaneous and skin-saving mastectomy. We solve the reconstruction either with an expander and in the second time by inserting a silicone implant, or directly by inserting the implant alone or in combination with the use of autologous tissue, depending on how further oncological treatment (chemotherapy or radiotherapy) is planned. Results: Between April 2017 and May 2020, 103 reconstructive surgeries were performed on 58 women with breast cancer and/or BRCA mutations. Of these, there were 52 immediate reconstructions for untreated tumors. A tissue expander was inserted in 27 women (46.6% of the group) with locally advanced tumors and the need for subsequent radiotherapy (18 immediate and 9 delayed reconstructions). Breast implants were used in 52 women (89.7% of the group) in a total of 80 implants. Breast reconstruction of own tissues was performed in 8 women, of which 5 operations within the immediate reconstruction. Postoperative complications occurred in 11 women and 15 corrective procedures were performed (12.7% of operations). Conclusion: Breast reconstruction is a comprehensive set of techniques by which any patient can develop a breast so that it does not depend on an epithelium. Patients with locally advanced disease who receive neoadjuvant chemotherapy and radiotherapy are at greater risk of complications. With the growing number of breast cancers, the demand for reconstructive procedures, especially immediate reconstructions, is increasing.

Citovat

VENTRUBA, Tomáš; Luboš MINÁŘ; Dagmar BRANČÍKOVÁ; Markéta PROTIVÁNKOVÁ a Pavel VENTRUBA. Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach. In ESMO Breast Cancer Congress, 2022 (3-5 May), Berlin, Germany. 2022. Dostupné z: https://doi.org/10.1016/j.annonc/2022.03.148.

@proceedings{1863155,
   author = {Ventruba, Tomáš and Minář, Luboš and Brančíková, Dagmar and Protivánková, Markéta and Ventruba, Pavel},
   booktitle = {ESMO Breast Cancer Congress, 2022 (3-5 May), Berlin, Germany.},
   doi = {https://doi.org/10.1016/j.annonc/2022.03.148},
   keywords = {breast-conserving surgery; BRCA mutation; immediate reconstruction; recurrence risk},
   language = {eng},
   title = {Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach.},
   year = {2022}
}

TY  - CONF
ID  - 1863155
AU  - Ventruba, Tomáš - Minář, Luboš - Brančíková, Dagmar - Protivánková, Markéta - Ventruba, Pavel
PY  - 2022
TI  - Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach.
KW  - breast-conserving surgery
KW  - BRCA mutation
KW  - immediate reconstruction
KW  - recurrence risk
N2  - Analysis of our approach to immediate breast reconstruction after mastectomy in women with breast cancer and / or BRCA mutations. Methods: We use the possibility of immediate breast reconstruction at the same time with subcutaneous and skin-saving mastectomy. We solve the reconstruction either with an expander and in the second time by inserting a silicone implant, or directly by inserting the implant alone or in combination with the use of autologous tissue, depending on how further oncological treatment (chemotherapy or radiotherapy) is planned. Results: Between April 2017 and May 2020, 103 reconstructive surgeries were performed on 58 women with breast cancer and/or BRCA mutations. Of these, there were 52 immediate reconstructions for untreated tumors. A tissue expander was inserted in 27 women (46.6% of the group) with locally advanced tumors and the need for subsequent radiotherapy (18 immediate and 9 delayed reconstructions). Breast implants were used in 52 women (89.7% of the group) in a total of 80 implants. Breast reconstruction of own tissues was performed in 8 women, of which 5 operations within the immediate reconstruction. Postoperative complications occurred in 11 women and 15 corrective procedures were performed (12.7% of operations). Conclusion: Breast reconstruction is a comprehensive set of techniques by which any patient can develop a breast so that it does not depend on an epithelium. Patients with locally advanced disease who receive neoadjuvant chemotherapy and radiotherapy are at greater risk of complications. With the growing number of breast cancers, the demand for reconstructive procedures, especially immediate reconstructions, is increasing.
ER  -

VENTRUBA, Tomáš; Luboš MINÁŘ; Dagmar BRANČÍKOVÁ; Markéta PROTIVÁNKOVÁ a Pavel VENTRUBA. Immediate breast reconstruction in patients with BRCA mutation and breast cancer - our approach. In \textit{ESMO Breast Cancer Congress, 2022 (3-5 May), Berlin, Germany.}. 2022. Dostupné z: https://doi.org/10.1016/j.annonc/2022.03.148.

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