J 2022

Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics

LÓPEZ CABEZA, María del Rocío; Melanie KAH; Renato GRILLO; Marek KOUTNY; Jan SALAC et al.

Základní údaje

Originální název

Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics

Autoři

LÓPEZ CABEZA, María del Rocío; Melanie KAH; Renato GRILLO; Marek KOUTNY; Jan SALAC; Zuzana BÍLKOVÁ; Mahleh EGHBALINEJAD a Jakub HOFMAN

Vydání

Environmental Science: Nano, CAMBRIDGE, ROYAL SOC CHEMISTRY, 2022, 2051-8153

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 7.300

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/22:00126162

Organizační jednotka

Přírodovědecká fakulta

EID Scopus

Klíčová slova anglicky

LIPID CARRIERS NLC; DRUG-RELEASE; NANOPARTICLES; MECHANISMS; PESTICIDES; DELIVERY; OIL

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 11. 6. 2025 06:25, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

In this work, tebuconazole and terbuthylazine were encapsulated in nanocarriers prepared from the polymers poly-epsilon-caprolactone, poly(3-hydroxybutyrate) and poly(acrylic acid)/polylactide, and in a nanostructured lipid carrier. The release kinetics of the prepared nanoformulations was assessed by the dialysis method and the results obtained from these release experiments were related to the durability of the nanoformulations. The outcomes suggested that the release of the active ingredients in these nanoformulations depended mainly on the interaction between the nanocarrier materials and the pesticides. In addition, it was found that the durability of the complex formed by tebuconazole encapsulated in poly(3-hydroxybutyrate) was affected by its dilution, the durability being shorter with the increase of dilution factor. The findings in this work could help the design of pesticide nanoformulations with certain durability according to the pesticide doses required in the field by selecting the appropriate nanocarrier material. Likewise, the results indicate the need to evaluate the release kinetics of the active ingredients under dilution of the nanoformulations, since the dilution in the mixing tank before application or in the soil during irrigation or rainfall events could influence the durability of the nanoformulations and as a consequence, their environmental risk assessment.

Návaznosti

EF17_043/0009632, projekt VaV
Název: CETOCOEN Excellence
GA18-19324S, projekt VaV
Název: Nanopesticidy v životním prostředí – porozumění jejich osudu, biodostupnosti, účinkům a rizikům v půdě a vodě
Investor: Grantová agentura ČR, Nanopesticides in the environment – understanding their fate, bioavailability, effects and risks in soil and water
857560, interní kód MU
(Kód CEP: EF17_043/0009632)
Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)
Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation
90121, velká výzkumná infrastruktura
Název: RECETOX RI