Surgical management of brachial plexus injuries and the
experimental reinnervation of the biceps muscle by the spinal
motoneurons through acellular nerve graft

D 1998

Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL

Základní údaje

Originální název

Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft

Název česky

Chirurgická rekonstrukce poškozeného brachiálního plexu a experimentální reinervace přes acelulární nervový štěp

Autoři

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL

Vydání

Bologna, 7th Congress IFSSH, s. 77-80, 1998

Nakladatel

Monduzzi Editore

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Itálie

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/98:00028148

Organizační jednotka

Lékařská fakulta

ISBN

8832305240

UT WoS

000077111100103

Klíčová slova anglicky

avulsion; acellular nerve graft

Štítky

acellular nerve graft, avulsion

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 19. 6. 2009 14:03, prof. RNDr. Petr Dubový, CSc.

Anotace

ORIG CZ

V originále

Thirty six patients with brachial plexus injury have been operated on. Results were very good in the case of infraganglionic lesions in 15 patients. Fair and good results were obtained in 72% of 18 patients with neurotization procedure of musculocutaneous and axillary nerves. Transfer of latissimus dorsi muscle instead of the biceps muscle was successful in another t cases. In the experimental animals the acellular nerve grafts was used to restore a functional reinnervation of the biceps brachii muscle by the motoneuron pool of the cervical spinal cord.. The musculocutaneous nerve stump was sutured with acellular nerve graft, the opposite end of which was inserted into the cervical spinal cord up to the avulsed C5 ventral root. Behavioural, electrophysiological as well as morphological methods proved the reconnection of the spinal motor neurons with the muscle end plates. Our results demonstrate that the acellular nerve graft repopulated by Schwann cells migrating from the nerve stump, stimulates the spinal motoneurons to formation of axonal sprouts. The regenerated axons are able to bridge a 4-cm long originally acellular nerve graft and reinnervate the biceps muscle.

Česky

Výsledky prezentují 36 operací provedených na pacientech a experimentální model avulse spinálních kořenů po rekonstrukci pomocí acelulárního nervového štěpu.

Návaznosti

IZ2605, projekt VaV

Název: Alternativní metody překonávání defektu poškozeného nervu

Investor: Ministerstvo zdravotnictví ČR, Alternativní metody překonávání defektu poškozeného nervu

Citovat

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL. Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft. In 7th Congress IFSSH. Bologna: Monduzzi Editore, 1998, s. 77-80. ISBN 8832305240.

@inproceedings{201088,
   author = {Haninec, Pavel and Dubový, Petr and Houšťava, Ladislav and Stejskal, Ladislav},
   address = {Bologna},
   booktitle = {7th Congress IFSSH},
   keywords = {avulsion; acellular nerve graft},
   language = {eng},
   location = {Bologna},
   isbn = {8832305240},
   pages = {77-80},
   publisher = {Monduzzi Editore},
   title = {Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft},
   year = {1998}
}

TY  - CONF
ID  - 201088
AU  - Haninec, Pavel - Dubový, Petr - Houšťava, Ladislav - Stejskal, Ladislav
PY  - 1998
TI  - Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft
PB  - Monduzzi Editore
CY  - Bologna
SN  - 8832305240
KW  - avulsion
KW  - acellular nerve graft
N2  - Thirty six patients with brachial plexus injury have been operated on. Results were very good in the case of infraganglionic lesions in 15 patients. Fair and good results were obtained in 72% of 18 patients with neurotization procedure of musculocutaneous and axillary nerves. Transfer of latissimus dorsi muscle instead of the biceps muscle was successful in another t cases. In the experimental animals the acellular nerve grafts was used to restore a functional reinnervation of the biceps brachii muscle by the motoneuron pool of the cervical spinal cord.. The musculocutaneous nerve stump was sutured with acellular nerve graft, the opposite end of which was inserted into the cervical spinal cord up to the avulsed C5 ventral root. Behavioural, electrophysiological as well as morphological methods proved the reconnection of the spinal motor neurons with the muscle end plates. Our results demonstrate that the acellular nerve graft repopulated by Schwann cells migrating from the nerve stump, stimulates the spinal motoneurons to formation of axonal sprouts. The regenerated axons are able to bridge a 4-cm long originally acellular nerve graft and reinnervate the biceps muscle.
ER  -

HANINEC, Pavel; Petr DUBOVÝ; Ladislav HOUŠŤAVA a Ladislav STEJSKAL. Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft. In \textit{7th Congress IFSSH}. Bologna: Monduzzi Editore, 1998, s.~77-80. ISBN~8832305240.

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