1,5-dicaffeoylquinic acid, an antioxidant component of Cynara cardunculus leaves

SLANINA, Jiří; Hana PAULOVÁ; Otakar HUMPA; Hana BOCHOŘÁKOVÁ a Eva TÁBORSKÁ. 1,5-dicaffeoylquinic acid, an antioxidant component of Cynara cardunculus leaves. Scripta Medica (BRNO). Brno: Lékařská fakulta Masarykovy univerzity, 1999, roč. 72, č. 1, s. 9-17. ISSN 1211-3395.

Základní údaje

Originální název

1,5-dicaffeoylquinic acid, an antioxidant component of Cynara cardunculus leaves

Autoři

SLANINA, Jiří; Hana PAULOVÁ; Otakar HUMPA; Hana BOCHOŘÁKOVÁ a Eva TÁBORSKÁ

Vydání

Scripta Medica (BRNO), Brno, Lékařská fakulta Masarykovy univerzity, 1999, 1211-3395

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Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10401 Organic chemistry

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Organizační jednotka

Lékařská fakulta

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Anotace

V originále

This study describes the isolation, identification and some antioxidant properties of 1,5-dicaffeoylquinic acid. The title compound was isolated from the methanolic extract of the leaves of Cynara cardunculus. The isolation was based on the selective extraction of 1,5-dicaffeoylquinic acid with diethylether from weakly acidic water-methanolic solution and on column chromatography. Its structure was elucidated by 1D and 2D H-NMR spectroscopy. Inhibition of hemolysis induced by hydrogen peroxide and the antiradical effect of both 1,5-dicaffeoylquinic acid and cynarin (1,3-dicaffeoylquinic acid) were studied. Cynarin is formed from 1,5-dicaffeoylquinic acid by transesterification during the solvent extraction. Antioxidant activity of dicaffeoylquinic acids in both systems was stronger than that of ascorbic acid.