| MAYORGA-MARTINEZ, Carmen C., Michaela FOJTŮ, Jan VYSKOCIL, Nam-Joon CHO and Martin PUMERA. Pollen-Based Magnetic Microrobots are Mediated by Electrostatic Forces to Attract, Manipulate, and Kill Cancer Cells. Advanced Functional Materials. Wrinheim: Wiley-VCH Verlag, 2022, vol. 32, No 46, p. 1-8. ISSN 1616-301X. Available from: https://dx.doi.org/10.1002/adfm.202207272. |
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@article{2217057,
author = {MayorgaandMartinez, Carmen C. and Fojtů, Michaela and Vyskocil, Jan and Cho, NamandJoon and Pumera, Martin},
article_location = {Wrinheim},
article_number = {46},
doi = {http://dx.doi.org/10.1002/adfm.202207272},
keywords = {biological microrobots; drug deliveries; hybrid robotics; magnetic micromotors},
language = {eng},
issn = {1616-301X},
journal = {Advanced Functional Materials},
title = {Pollen-Based Magnetic Microrobots are Mediated by Electrostatic Forces to Attract, Manipulate, and Kill Cancer Cells},
url = {https://onlinelibrary.wiley.com/doi/10.1002/adfm.202207272},
volume = {32},
year = {2022}
}
TY - JOUR
ID - 2217057
AU - Mayorga-Martinez, Carmen C. - Fojtů, Michaela - Vyskocil, Jan - Cho, Nam-Joon - Pumera, Martin
PY - 2022
TI - Pollen-Based Magnetic Microrobots are Mediated by Electrostatic Forces to Attract, Manipulate, and Kill Cancer Cells
JF - Advanced Functional Materials
VL - 32
IS - 46
SP - 1-8
EP - 1-8
PB - Wiley-VCH Verlag
SN - 1616301X
KW - biological microrobots
KW - drug deliveries
KW - hybrid robotics
KW - magnetic micromotors
UR - https://onlinelibrary.wiley.com/doi/10.1002/adfm.202207272
N2 - Naturally occurring micro/nanoparticles provide an incredible array of potential sources when preparing hybrid micro/nanorobots and their intrinsic properties can be exploited as multitasking functionalities of modern robotics as well as ensuring their mass production availability. Herein, magnetic biological bots (BioBots) prepared from defatted sunflower pollen microparticles by ferromagnetic metal layer evaporation on one side of its surface are described. It is demonstrated that the methodology employed introduces magnetic properties to sunflower pollen microparticles-based BioBots and enable their magnetic actuation. Interestingly, as-prepared magnetic sunflower pollen-based BioBots can naturally attract cancer cells due to their opposite charges (positive and negative, respectively). Such attracted cancer cells can then be transported by microrobots. This strong attraction also allows the delivery of drugs intended to kill the cancer cells. Sunflower-based BioBots can be fabricated in large quantities, and are naturally programmable, making them promising candidates for cancer cell therapy.
ER -
MAYORGA-MARTINEZ, Carmen C., Michaela FOJTŮ, Jan VYSKOCIL, Nam-Joon CHO and Martin PUMERA. Pollen-Based Magnetic Microrobots are Mediated by Electrostatic Forces to Attract, Manipulate, and Kill Cancer Cells. \textit{Advanced Functional Materials}. Wrinheim: Wiley-VCH Verlag, 2022, vol.~32, No~46, p.~1-8. ISSN~1616-301X. Available from: https://dx.doi.org/10.1002/adfm.202207272.
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