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@proceedings{2217373, author = {Havránková, Eva and Jampílek, Josef and Csöllei, Jozef and Garaj, Vladimír and Supuran, Claudiu T.}, booktitle = {SAL 2022}, keywords = {carbonic anhydrases; vancomycin-resistant enterococci; anti-VRE agents; triazinyl-benzenesulfonamides}, language = {eng}, title = {NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS}, url = {https://www.pharm.muni.cz/veda-a-vyzkum/sal-2022/attendee-information}, year = {2022} }
TY - CONF ID - 2217373 AU - Havránková, Eva - Jampílek, Josef - Csöllei, Jozef - Garaj, Vladimír - Supuran, Claudiu T. PY - 2022 TI - NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS KW - carbonic anhydrases KW - vancomycin-resistant enterococci KW - anti-VRE agents KW - triazinyl-benzenesulfonamides UR - https://www.pharm.muni.cz/veda-a-vyzkum/sal-2022/attendee-information N2 - Carbonic anhydrases are metalloenzymes catalysing the reversible hydration of CO2, thereby affect the pH and affecting related physiological processes in various organisms. In pathogenic bacteria, CAs play an important role in survival and growth. Inhibition of bacterial CAs leads to growth retardation, growth defects and makes bacteria vulnerable to host defense mechanisms. Bacterial CAs are therefore a very promising target in the search for new antibiotics. ER -
HAVRÁNKOVÁ, Eva, Josef JAMPÍLEK, Jozef CSÖLLEI, Vladimír GARAJ and Claudiu T. SUPURAN. NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS. In \textit{SAL 2022}. 2022.
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