2022
Comparison of gross pathology inspection and 9.4 Tmagnetic resonance imaging in theevaluation of radiofrequency ablationlesions in the left ventricle of theswine heart.
ODEHNALOVÁ, Eva; Lucie VALÍKOVÁ; Guido CALUORI; Tomáš KULÍK; Veronika ŘÍMALOVÁ et. al.Základní údaje
Originální název
Comparison of gross pathology inspection and 9.4 Tmagnetic resonance imaging in theevaluation of radiofrequency ablationlesions in the left ventricle of theswine heart.
Autoři
ODEHNALOVÁ, Eva (203 Česká republika); Lucie VALÍKOVÁ (203 Česká republika); Guido CALUORI (380 Itálie, domácí); Tomáš KULÍK (203 Česká republika); Veronika ŘÍMALOVÁ (203 Česká republika); Tomasz JADCZYK (616 Polsko); Eva DRAŽANOVÁ (203 Česká republika); Iveta PAVLOVA (203 Česká republika); Martin PEŠL (203 Česká republika, domácí); Václav KUBEŠ (203 Česká republika) a Zdeněk STÁREK (203 Česká republika, garant)
Vydání
FRONTIERS IN PHYSIOLOGY, LAUSANNE, FRONTIERS MEDIA SA, 2022, 1664-042X
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Švýcarsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 4.000
Kód RIV
RIV/00216224:14110/22:00127023
Organizační jednotka
Lékařská fakulta
UT WoS
000888266600001
EID Scopus
2-s2.0-85141134445
Klíčová slova anglicky
evaluation of radiofrequency ablation lesions; comparison of methods; gross pathology inspection; high-resolution MRI evaluation; animal experiments; catheter ablation of arrhythmias; ex vivo MRI scanning
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 3. 4. 2023 12:00, Mgr. Tereza Miškechová
Anotace
V originále
Aims: Gross pathology inspection (patho) is the gold standard for the morphological evaluation of focal myocardial pathology. Examination with 9.4 T magnetic resonance imaging (MRI) is a new method for very accurate display of myocardial pathology. The aim of this study was to demonstrate that lesions can be measured on high-resolution MRI images with the same accuracy as on pathological sections and compare these two methods for the evaluation of radiofrequency (RF) ablation lesion dimensions in swine heart tissue during animal experiment. Methods: Ten pigs underwent radiofrequency ablations in the left ventricle during animal experiment. After animal euthanasia, hearts were explanted, flushed with ice-cold cardioplegic solution to relax the whole myocardium, fixed in 10% formaldehyde and scanned with a 9.4 T magnetic resonance system. Anatomical images were processed using ImageJ software. Subsequently, the hearts were sliced, slices were photographed and measured in ImageJ software. Different dimensions and volumes were compared. Results: The results of both methods were statistically compared. Depth by MRI was 8.771 ± 2.595 mm and by patho 9.008 ± 2.823 mm; p = 0.198. Width was 10.802 ± 2.724 mm by MRI and 11.125 ± 2.801 mm by patho; p = 0.049. Estuary was 2.006 ± 0.867 mm by MRI and 2.001 ± 0.872 mm by patho; p = 0.953. The depth at the maximum diameter was 4.734 ± 1.532 mm on MRI and 4.783 ± 1.648 mm from the patho; p = 0.858. The volumes of the lesions calculated using a formula were 315.973 ± 257.673 mm 3 for MRI and 355.726 ± 255.860 mm 3 for patho; p = 0.104. Volume directly measured from MRI with the “point-by-point” method was 671.702 ± 362.299 mm. Conclusion: Measurements obtained from gross pathology inspection and MRI are fully comparable. The advantage of MRI is that it is a non-destructive method enabling repeated measurements in all possible anatomical projections.
Návaznosti
| LM2015062, projekt VaV |
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| MUNI/A/1462/2021, interní kód MU |
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