J 2022

AEON.py: Python library for attractor analysis in asynchronous Boolean networks

BENEŠ, Nikola; Luboš BRIM; Ondřej HUVAR; Samuel PASTVA; David ŠAFRÁNEK et. al.

Basic information

Original name

AEON.py: Python library for attractor analysis in asynchronous Boolean networks

Authors

BENEŠ, Nikola (203 Czech Republic, belonging to the institution); Luboš BRIM (203 Czech Republic, belonging to the institution); Ondřej HUVAR (203 Czech Republic, belonging to the institution); Samuel PASTVA (703 Slovakia, belonging to the institution); David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution) and Eva ŠMIJÁKOVÁ (703 Slovakia, belonging to the institution)

Edition

BIOINFORMATICS, UK, OXFORD UNIV PRESS, 2022, 1367-4803

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10201 Computer sciences, information science, bioinformatics

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

is not subject to a state or trade secret

References:

Impact factor

Impact factor: 5.800

RIV identification code

RIV/00216224:14330/22:00127100

Organization unit

Faculty of Informatics

UT WoS

000857476100001

EID Scopus

2-s2.0-85141004669

Keywords in English

Boolean Networks; Attractors; Software

Tags

International impact, Reviewed
Changed: 28/3/2023 12:03, RNDr. Pavel Šmerk, Ph.D.

Abstract

In the original language

AEON.py is a Python library for the analysis of the long-term behaviour in very large asynchronous Boolean networks. It provides significant computational improvements over the state-of-the-art methods for attractor detection. Furthermore, it admits the analysis of partially specified Boolean networks with uncertain update functions. It also includes techniques for identifying viable source-target control strategies and the assessment of their robustness with respect to parameter perturbations.

Links

MUNI/A/1145/2021, interní kód MU
Name: Rozsáhlé výpočetní systémy: modely, aplikace a verifikace XI. (Acronym: SV-FI MAV XI.)
Investor: Masaryk University
MUNI/G/1771/2020, interní kód MU
Name: Computational reconstruction of mechanistic framework underlying receptor tyrosine kinase function in signal transduction (Acronym: FGFSIGMOD)
Investor: Masaryk University, INTERDISCIPLINARY - Interdisciplinary research projects