Resistance of Streptococcus suis Isolates from the Czech
Republic during 2018-2022

J 2022

Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022

NEDBALCOVA, Katerina; Ivana KUCHAROVICOVA; Monika ZOUHAROVA; Katarina MATIASKOVA; Natálie KRÁLOVÁ et al.

Základní údaje

Originální název

Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022

Autoři

NEDBALCOVA, Katerina; Ivana KUCHAROVICOVA; Monika ZOUHAROVA; Katarina MATIASKOVA; Natálie KRÁLOVÁ; Marek BRYCHTA; Bronislav SIMEK; Tomas PECHA; Hana PLODKOVA a Jan MATIASOVIC

Vydání

Antibiotics, MDPI, 2022, 2079-6382

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

40301 Veterinary science

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.800

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/22:00127382

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

antimicrobial susceptibility testing; serotypization; minimal inhibitory concentration; infectious disease; pigs

Štítky

14314010, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 12. 2022 09:31, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

A determination of susceptibility/resistance to antimicrobials via serotype was carried out in 506 field isolates of Streptococcus suis, originating from pig farms in the Czech Republic in the period 2018–2022. A very high level of susceptibility of S. suis isolates was found to amoxicillin, in combination with clavulanic acid and sulfamethoxazole potentiated with trimethoprim. None of the tested isolates were resistant to these antimicrobial substances. Only two isolates were found to be intermediately resistant to enrofloxacin in 2020. With regard to ceftiofur, one isolate was intermediately resistant in 2020 and 2022, and two isolates were intermediately resistant in 2018 and 2021. A low level of resistance was detected to ampicillin (0.6% in 2021) and to florfenicol (1.15% in 2019; 1.3% in 2022). With regard to penicillin, a medium level of resistance was detected in 2018 (10.6%), but a low level of resistance was found in the following years (7.0% in 2019; 3.1% in 2020; 3.3% in 2021; 3.9% in 2022). On the contrary, a high or very high level of resistance was found to tetracycline (66.0% in 2018; 65.1% in 2019; 44.35% in 2020; 46.4% in 2021; 54.0% in 2022). Using molecular and serological methods, serotype 7 (16.4%) was determined to be predominant among S. suis isolates, followed by serotypes 1/2, 2, 9, 4, 3, 1, 29, 16, and 31 (10.7%; 8.5%; 5.7%; 5.5%; 4.5%; 4.3%; 3.6%; 3.4%; 3.4%, respectively). Other serotypes were identified among the investigated strains either rarely (up to 10 cases) or not at all. A relatively high percentage of isolates were detected as non-typeable (79 isolates; 15.6%). Dependence of resistance upon serotype assignment could not be proven in all but serotype 31, wherein all isolates (n = 17) were resistant or intermediately resistant to clindamycin, tilmycosin, tulathromycin, and tetracycline. The resistance to clindamycin and tetracycline may be related to the high consumption of these antibiotics on pig farms at present or in previous years. Macrolides (tilmicosin and tulathromycin) and tiamulin are not suitable for the treatment of streptococcal infections, but are used on pig farms to treat respiratory infections caused by gram-negative bacteria, so they were included in the study.

Citovat

NEDBALCOVA, Katerina; Ivana KUCHAROVICOVA; Monika ZOUHAROVA; Katarina MATIASKOVA; Natálie KRÁLOVÁ; Marek BRYCHTA; Bronislav SIMEK; Tomas PECHA; Hana PLODKOVA a Jan MATIASOVIC. Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022. Antibiotics. MDPI, 2022, roč. 11, č. 9, s. 1-15. ISSN 2079-6382. Dostupné z: https://doi.org/10.3390/antibiotics11091214.

@article{2237992,
   author = {Nedbalcova, Katerina and Kucharovicova, Ivana and Zouharova, Monika and Matiaskova, Katarina and Králová, Natálie and Brychta, Marek and Simek, Bronislav and Pecha, Tomas and Plodkova, Hana and Matiasovic, Jan},
   article_number = {9},
   doi = {https://doi.org/10.3390/antibiotics11091214},
   keywords = {antimicrobial susceptibility testing; serotypization; minimal inhibitory concentration; infectious disease; pigs},
   language = {eng},
   issn = {2079-6382},
   journal = {Antibiotics},
   title = {Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022},
   url = {https://www.mdpi.com/2079-6382/11/9/1214},
   volume = {11},
   year = {2022}
}

TY  - JOUR
ID  - 2237992
AU  - Nedbalcova, Katerina - Kucharovicova, Ivana - Zouharova, Monika - Matiaskova, Katarina - Králová, Natálie - Brychta, Marek - Simek, Bronislav - Pecha, Tomas - Plodkova, Hana - Matiasovic, Jan
PY  - 2022
TI  - Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022
JF  - Antibiotics
VL  - 11
IS  - 9
SP  - 1-15
EP  - 1-15
PB  - MDPI
SN  - 20796382
KW  - antimicrobial susceptibility testing
KW  - serotypization
KW  - minimal inhibitory concentration
KW  - infectious disease
KW  - pigs
UR  - https://www.mdpi.com/2079-6382/11/9/1214
N2  - A determination of susceptibility/resistance to antimicrobials via serotype was carried out in 506 field isolates of Streptococcus suis, originating from pig farms in the Czech Republic in the period 2018–2022. A very high level of susceptibility of S. suis isolates was found to amoxicillin, in combination with clavulanic acid and sulfamethoxazole potentiated with trimethoprim. None of the tested isolates were resistant to these antimicrobial substances. Only two isolates were found to be intermediately resistant to enrofloxacin in 2020. With regard to ceftiofur, one isolate was intermediately resistant in 2020 and 2022, and two isolates were intermediately resistant in 2018 and 2021. A low level of resistance was detected to ampicillin (0.6% in 2021) and to florfenicol (1.15% in 2019; 1.3% in 2022). With regard to penicillin, a medium level of resistance was detected in 2018 (10.6%), but a low level of resistance was found in the following years (7.0% in 2019; 3.1% in 2020; 3.3% in 2021; 3.9% in 2022). On the contrary, a high or very high level of resistance was found to tetracycline (66.0% in 2018; 65.1% in 2019; 44.35% in 2020; 46.4% in 2021; 54.0% in 2022). Using molecular and serological methods, serotype 7 (16.4%) was determined to be predominant among S. suis isolates, followed by serotypes 1/2, 2, 9, 4, 3, 1, 29, 16, and 31 (10.7%; 8.5%; 5.7%; 5.5%; 4.5%; 4.3%; 3.6%; 3.4%; 3.4%, respectively). Other serotypes were identified among the investigated strains either rarely (up to 10 cases) or not at all. A relatively high percentage of isolates were detected as non-typeable (79 isolates; 15.6%). Dependence of resistance upon serotype assignment could not be proven in all but serotype 31, wherein all isolates (n = 17) were resistant or intermediately resistant to clindamycin, tilmycosin, tulathromycin, and tetracycline. The resistance to clindamycin and tetracycline may be related to the high consumption of these antibiotics on pig farms at present or in previous years. Macrolides (tilmicosin and tulathromycin) and tiamulin are not suitable for the treatment of streptococcal infections, but are used on pig farms to treat respiratory infections caused by gram-negative bacteria, so they were included in the study.
ER  -

NEDBALCOVA, Katerina; Ivana KUCHAROVICOVA; Monika ZOUHAROVA; Katarina MATIASKOVA; Natálie KRÁLOVÁ; Marek BRYCHTA; Bronislav SIMEK; Tomas PECHA; Hana PLODKOVA a Jan MATIASOVIC. Resistance of Streptococcus suis Isolates from the Czech Republic during 2018-2022. \textit{Antibiotics}. MDPI, 2022, roč.~11, č.~9, s.~1-15. ISSN~2079-6382. Dostupné z: https://doi.org/10.3390/antibiotics11091214.

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