TORRENTE, María, Pedro A SOUSA, Roberto HERNÁNDEZ, Mariola BLANCO, Virginia Calvo Ana COLLAZO, Gracinda R GUERREIRO, Beatriz NÚÑEZ, Joao PIMENTAO, Juan Cristóbal SÁNCHEZ, Manuel CAMPOS, Luca COSTABELLO, Vít NOVÁČEK, Ernestina MENASALVAS, María Esther VIDAL, Mariano PROVENCIO and Virginia CALVO. An Artificial Intelligence-Based Tool for Data Analysis and Prognosis in Cancer Patients: Results from the Clarify Study. CANCERS. SWITZERLAND: MDPI, 2022, vol. 14, No 16, p. 1-10. ISSN 2072-6694. Available from: https://dx.doi.org/10.3390/cancers14164041.
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Basic information
Original name An Artificial Intelligence-Based Tool for Data Analysis and Prognosis in Cancer Patients: Results from the Clarify Study
Authors TORRENTE, María, Pedro A SOUSA, Roberto HERNÁNDEZ, Mariola BLANCO, Virginia Calvo Ana COLLAZO, Gracinda R GUERREIRO, Beatriz NÚÑEZ, Joao PIMENTAO, Juan Cristóbal SÁNCHEZ, Manuel CAMPOS, Luca COSTABELLO, Vít NOVÁČEK (203 Czech Republic, guarantor, belonging to the institution), Ernestina MENASALVAS, María Esther VIDAL, Mariano PROVENCIO and Virginia CALVO.
Edition CANCERS, SWITZERLAND, MDPI, 2022, 2072-6694.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW original online article
Impact factor Impact factor: 5.200
RIV identification code RIV/00216224:14330/22:00127570
Organization unit Faculty of Informatics
Doi http://dx.doi.org/10.3390/cancers14164041
UT WoS 000846265900001
Keywords (in Czech) artificial intelligence; data integration; cancer patients; patient stratification; precision oncology; decision support system
Keywords in English artificial intelligence; data integration; cancer patients; patient stratification; precision oncology; decision support system
Tags Artificial Intelligence, knowledge graphs, machine learning, medical informatics
Tags International impact, Reviewed
Changed by Changed by: RNDr. Pavel Šmerk, Ph.D., učo 3880. Changed: 6/4/2023 13:36.
Abstract
Background: Artificial intelligence (AI) has contributed substantially in recent years to the resolution of different biomedical problems, including cancer. However, AI tools with significant and widespread impact in oncology remain scarce. The goal of this study is to present an AI-based solution tool for cancer patients data analysis that assists clinicians in identifying the clinical factors associated with poor prognosis, relapse and survival, and to develop a prognostic model that stratifies patients by risk. Materials and Methods: We used clinical data from 5275 patients diagnosed with non-small cell lung cancer, breast cancer, and non-Hodgkin lymphoma at Hospital Universitario Puerta de Hierro-Majadahonda. Accessible clinical parameters measured with a wearable device and quality of life questionnaires data were also collected. Results: Using an AI-tool, data from 5275 cancer patients were analyzed, integrating clinical data, questionnaires data, and data collected from wearable devices. Descriptive analyses were performed in order to explore the patients’ characteristics, survival probabilities were calculated, and a prognostic model identified low and high-risk profile patients. Conclusion: Overall, the reconstruction of the population’s risk profile for the cancer-specific predictive model was achieved and proved useful in clinical practice using artificial intelligence. It has potential application in clinical settings to improve risk stratification, early detection, and surveillance management of cancer patients.
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