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@article{2249109,
author = {Kolčava, Jan and Rajdová, Aneta and Vlčková, Eva and Štourač, Pavel and Bednařík, Josef},
article_location = {London},
article_number = {1},
doi = {http://dx.doi.org/10.1186/s12883-022-02837-5},
keywords = {Demyelinating diseases; Myelin-oligodendrocyte glycoprotein; Evoked potentials; Magnetic resonance imaging; Case report},
language = {eng},
issn = {1471-2377},
journal = {BMC Neurology},
title = {Relapsing MRI-negative myelitis associated with myelin-oligodendrocyte glycoprotein autoantibodies: a case report},
url = {https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-022-02837-5},
volume = {22},
year = {2022}
}
TY - JOUR
ID - 2249109
AU - Kolčava, Jan - Rajdová, Aneta - Vlčková, Eva - Štourač, Pavel - Bednařík, Josef
PY - 2022
TI - Relapsing MRI-negative myelitis associated with myelin-oligodendrocyte glycoprotein autoantibodies: a case report
JF - BMC Neurology
VL - 22
IS - 1
SP - 1-6
EP - 1-6
PB - Biomed Central Ltd.
SN - 14712377
KW - Demyelinating diseases
KW - Myelin-oligodendrocyte glycoprotein
KW - Evoked potentials
KW - Magnetic resonance imaging
KW - Case report
UR - https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-022-02837-5
N2 - Background Serum antibodies to myelin-oligodendrocyte glycoprotein (MOG) are biomarkers of MOG-IgG-associated disorder (MOGAD), a demyelinating disease distinct from both multiple sclerosis and aquaporin-4-IgG neuromyelitis optica spectrum disorder. The phenotype of MOGAD is broad and includes optic neuritis, transverse myelitis, and acute demyelinating encephalomyelitis. Myelitis is common with MOGAD and typically results in acute and severe disability, although prospects for recovery are often favorable with prompt immunotherapy. Case presentation This contribution presents a unique case report of a young male patient exhibiting relapsing myelitis with normal spinal cord and brain magnetic resonance imaging. Comprehensive diagnostic assessment revealed myelin-oligodendrocyte glycoprotein-IgG-associated disorder. Conclusion MOGAD is one of the conditions which should be considered in MRI-negative myelitis. The diagnosis, however, may prove difficult, especially if the patient is not exhibiting other neurological symptoms of MOGAD. Conus or epiconus involvement is common in MOGAD; the patient reported herein exhibited incomplete rostral epiconus symptoms which, together with somatosensory evoked potential abnormalities, led to the diagnosis.
ER -
KOLČAVA, Jan, Aneta RAJDOVÁ, Eva VLČKOVÁ, Pavel ŠTOURAČ a Josef BEDNAŘÍK. Relapsing MRI-negative myelitis associated with myelin-oligodendrocyte glycoprotein autoantibodies: a case report. \textit{BMC Neurology}. London: Biomed Central Ltd., 2022, roč.~22, č.~1, s.~1-6. ISSN~1471-2377. Dostupné z: https://dx.doi.org/10.1186/s12883-022-02837-5.
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