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@article{2249620,
author = {Babula, Petr and Križanová, Oľga},
article_location = {Bratislava},
article_number = {2},
doi = {http://dx.doi.org/10.4149/neo_2022_220127N121},
keywords = {calcium transport systems; cell death; cancer},
language = {eng},
issn = {0028-2685},
journal = {Neoplasma},
title = {Involvement of calcium signaling in different types of cell death in cancer},
url = {http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=7567&category_id=180&option=com_virtuemart&vmcchk=1&Itemid=1},
volume = {69},
year = {2022}
}
TY - JOUR
ID - 2249620
AU - Babula, Petr - Križanová, Oľga
PY - 2022
TI - Involvement of calcium signaling in different types of cell death in cancer
JF - Neoplasma
VL - 69
IS - 2
SP - 264-273
EP - 264-273
PB - Slovenská akademie vied
SN - 00282685
KW - calcium transport systems
KW - cell death
KW - cancer
UR - http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=7567&category_id=180&option=com_virtuemart&vmcchk=1&Itemid=1
N2 - Programmed cell death is a basic feature of chemotherapeutic (and also radiotherapeutic) intervention. Induction of cell death in tumor cells aims to kill preferentially the tumor cells, with minimal impact on the normal cells. Although apoptosis is the most obvious type of cell death induced by chemotherapeutics, several other types can also be activated, especially in conditions, where cells are resistant to apoptosis induction. Calcium signaling was shown to play an indisputable role in the activation of different types of cell death. Local increase of the calcium in time and precise place of this increase is secured by calcium transport systems. In this review, we summarized the involvement of some calcium transport systems in apoptosis, autophagy, necroptosis, ferroptosis, and mitophagy during cancer development and treatment.
ER -
BABULA, Petr a Oľga KRIŽANOVÁ. Involvement of calcium signaling in different types of cell death in cancer. \textit{Neoplasma}. Bratislava: Slovenská akademie vied, 2022, roč.~69, č.~2, s.~264-273. ISSN~0028-2685. Dostupné z: https://dx.doi.org/10.4149/neo\_{}2022\_{}220127N121.
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