J 2022

When time does not heal all wounds-the use of medical grade honey in wound healing: a case series

NAIK, Piyu Parth, Daniela CHRYSOSTOMOU, Mirela CINTEZA, Andrea POKORNÁ, Niels A. J. CREMERS et. al.

Základní údaje

Originální název

When time does not heal all wounds-the use of medical grade honey in wound healing: a case series

Autoři

NAIK, Piyu Parth, Daniela CHRYSOSTOMOU, Mirela CINTEZA, Andrea POKORNÁ (203 Česká republika, domácí) a Niels A. J. CREMERS (garant)

Vydání

Journal of Wound Care, London, MA Healthcare Limited, 2022, 0969-0700

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30216 Dermatology and venereal diseases

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.900

Kód RIV

RIV/00216224:14110/22:00128420

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000825216500003

Klíčová slova anglicky

alternative therapy; antibiotic; antibiotic replacement; chronic; chronic venous insufficiency; complementary therapy; hard-to-heal; honey; infection; medical grade honey; quality of life; wound; wound care; wound dressing; wound healing

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 31. 1. 2023 09:06, Mgr. Tereza Miškechová

Anotace

V originále

Objective: Hard-to-heal wounds can be caused by persistent infections or an excess of inflammatory cytokines, proteases and oxidants, and can severely impact the quality of life pop of patients. Due to the paucity of effective treatments and increased resistance to antibiotics, new and improved therapies are required to resolve infections and to simultaneously enhance the healing trajectory. Medical grade honey (MGH) may be a novel and effective treatment approach. Methods: In this case series, we have described six cases of hard-to-heal wounds, and discussed the effects of MGH on infection, wound healing and factors influencing patient QoL (pain, odour and exudate). In all cases, the wounds had persisted for a long period, and previous treatments had been ineffective. Most of the patients had comorbidities, and the majority of the wounds were contaminated with (multiresistant) bacteria, both of which contributed to non-healing. All wounds were treated with L-Mesitran (MGH-based wound care products, Triticum Exploitatie By, the Netherlands) either as monotherapy or as a complementary therapy. Results: Hard-to-heal wounds started healing, infection was controlled and QoL was strongly improved (malodour, exudate levels and pain swiftly decreased) after the application of the MGH. All wounds healed relatively quickly, considering the severity of the wounds and general health of the patients. Conclusion: In this study, MGH was a useful alternative or complementary therapy to antibiotics and expedited the healing of hard-to-heal wounds.