Multidisciplinary approach to identification of Gregor Johann
Mendel's skeletal remains

J 2022

Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains

FIALOVÁ, Dana; Eva DROZDOVÁ; Eva CHOCHOLOVÁ; Kristýna BRZOBOHATÁ; Filip PARDY et al.

Základní údaje

Originální název

Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains

Autoři

Vydání

Folia Mendeliana : supplementum ad Acta Musei Moraviae, Moravian Museum Brno, 2022, 0085-0748

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/22:00128534

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Gregor Johann Mendel; mitogenome; palaeogenomics

Příznaky

Mezinárodní význam

Změněno: 16. 2. 2023 11:52, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Skeletal remains of five members of the Order of St. Augustine were found in the tomb at the Central Cemetery in Brno during an archaeological excavation in 2021. The aim was to identify Gregor Johann Mendel. Archaeological, anthropological, and genetic approaches were used for this purpose. However, the most reliable method to distinguish his skeletal remains was genetic identification. Specifically, the whole mitochondrial DNA (mitogenome) was read by next-generation sequencing (NGS). The mitogenomes of all five men and twenty DNA samples from Mendel’s personal belongings (e.g., hair from his books and swabs) were compared. A match was found with one hair. The positive identification paved the way for proceeding with the project and reading his entire genome.

Návaznosti

LM2015085, projekt VaV

Název: CERIT Scientific Cloud (Akronym: CERIT-SC)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CERIT Scientific Cloud

LM2018132, projekt VaV

Název: Národní centrum lékařské genomiky (Akronym: NCLG)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Národní centrum lékařské genomiky

Citovat

FIALOVÁ, Dana; Eva DROZDOVÁ; Eva CHOCHOLOVÁ; Kristýna BRZOBOHATÁ; Filip PARDY; Anna ŠENOVSKÁ; Hana SVOBODOVÁ; Kateřina NOVOTNÁ; Boris TICHÝ; Marek PEŠKA; Antonín ZŮBEK; Michael DOUBEK a Šárka POSPÍŠILOVÁ. Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains. Folia Mendeliana : supplementum ad Acta Musei Moraviae. Moravian Museum Brno, 2022, roč. 58, č. 1, s. 29-36. ISSN 0085-0748.

@article{2252430,
   author = {Fialová, Dana and Drozdová, Eva and Chocholová, Eva and Brzobohatá, Kristýna and Pardy, Filip and Šenovská, Anna and Svobodová, Hana and Novotná, Kateřina and Tichý, Boris and Peška, Marek and Zůbek, Antonín and Doubek, Michael and Pospíšilová, Šárka},
   article_number = {1},
   keywords = {Gregor Johann Mendel; mitogenome; palaeogenomics},
   language = {eng},
   issn = {0085-0748},
   journal = {Folia Mendeliana : supplementum ad Acta Musei Moraviae},
   title = {Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains},
   url = {http://www.mzm.cz/e-shop?ai%5Baction%5D=list&ai%5Bcontroller%5D=Catalog&ai%5Bf_catid%5D=23&ai%5Bf_name%5D=Folia-Mendeliana},
   volume = {58},
   year = {2022}
}

TY  - JOUR
ID  - 2252430
AU  - Fialová, Dana - Drozdová, Eva - Chocholová, Eva - Brzobohatá, Kristýna - Pardy, Filip - Šenovská, Anna - Svobodová, Hana - Novotná, Kateřina - Tichý, Boris - Peška, Marek - Zůbek, Antonín - Doubek, Michael - Pospíšilová, Šárka
PY  - 2022
TI  - Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains
JF  - Folia Mendeliana : supplementum ad Acta Musei Moraviae
VL  - 58
IS  - 1
SP  - 29-36
EP  - 29-36
PB  - Moravian Museum Brno
SN  - 00850748
KW  - Gregor Johann Mendel
KW  - mitogenome
KW  - palaeogenomics
UR  - http://www.mzm.cz/e-shop?ai%5Baction%5D=list&ai%5Bcontroller%5D=Catalog&ai%5Bf_catid%5D=23&ai%5Bf_name%5D=Folia-Mendeliana
N2  - Skeletal remains of five members of the Order of St. Augustine were found in the tomb at the Central Cemetery in Brno during an archaeological excavation in 2021. The aim was to identify Gregor Johann Mendel. Archaeological, anthropological, and genetic approaches were used for this purpose. However, the most reliable method to distinguish his skeletal remains was genetic identification. Specifically, the whole mitochondrial DNA (mitogenome) was read by next-generation sequencing (NGS). The mitogenomes of all five men and twenty DNA samples from Mendel’s personal belongings (e.g., hair from his books and swabs) were compared. A match was found with one hair. The positive identification paved the way for proceeding with the project and reading his entire genome.
ER  -

FIALOVÁ, Dana; Eva DROZDOVÁ; Eva CHOCHOLOVÁ; Kristýna BRZOBOHATÁ; Filip PARDY; Anna ŠENOVSKÁ; Hana SVOBODOVÁ; Kateřina NOVOTNÁ; Boris TICHÝ; Marek PEŠKA; Antonín ZŮBEK; Michael DOUBEK a Šárka POSPÍŠILOVÁ. Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains. \textit{Folia Mendeliana : supplementum ad Acta Musei Moraviae}. Moravian Museum Brno, 2022, roč.~58, č.~1, s.~29-36. ISSN~0085-0748.

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