| VONDRAKOVA, Jana, Michaela FROLIKOVA, Lukas DED, Jiri CERNY, Pavla POSTLEROVA, Veronika PALENIKOVA, Ondrej SIMONIK, Zuzana NAHACKA, Krystof BASUS, Eliska VALASKOVA, Radek MACHAN, Allan PACEY, Zuzana HOLUBCOVÁ, Pavel KOUBEK, Zuzana EZROVA, Soojin PARK, Ruiwu LIU, Raghavendran PARTHA, Nathan CLARK, Jiri NEUZIL, Masahito IKAWA, Kent ERICKSON, Kit S. LAM, Harry MOORE a Katerina KOMRSKOVA. MAIA; Fc receptor-like 3; supersedes JUNO as IZUMO1 receptor during human fertilization. Science advances. WASHINGTON: American Association for the Advancement of Science, 2022, roč. 8, č. 36, s. 1-16. ISSN 2375-2548. Dostupné z: https://dx.doi.org/10.1126/sciadv.abn0047. |
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@article{2253682,
author = {Vondrakova, Jana and Frolikova, Michaela and Ded, Lukas and Cerny, Jiri and Postlerova, Pavla and Palenikova, Veronika and Simonik, Ondrej and Nahacka, Zuzana and Basus, Krystof and Valaskova, Eliska and Machan, Radek and Pacey, Allan and Holubcová, Zuzana and Koubek, Pavel and Ezrova, Zuzana and Park, Soojin and Liu, Ruiwu and Partha, Raghavendran and Clark, Nathan and Neuzil, Jiri and Ikawa, Masahito and Erickson, Kent and Lam, Kit S. and Moore, Harry and Komrskova, Katerina},
article_location = {WASHINGTON},
article_number = {36},
doi = {http://dx.doi.org/10.1126/sciadv.abn0047},
keywords = {human fertilization; MAIA; Fc receptor-like 3; supersedes JUNO; IZUMO1},
language = {eng},
issn = {2375-2548},
journal = {Science advances},
title = {MAIA; Fc receptor-like 3; supersedes JUNO as IZUMO1 receptor during human fertilization},
url = {https://www.science.org/doi/10.1126/sciadv.abn0047},
volume = {8},
year = {2022}
}
TY - JOUR
ID - 2253682
AU - Vondrakova, Jana - Frolikova, Michaela - Ded, Lukas - Cerny, Jiri - Postlerova, Pavla - Palenikova, Veronika - Simonik, Ondrej - Nahacka, Zuzana - Basus, Krystof - Valaskova, Eliska - Machan, Radek - Pacey, Allan - Holubcová, Zuzana - Koubek, Pavel - Ezrova, Zuzana - Park, Soojin - Liu, Ruiwu - Partha, Raghavendran - Clark, Nathan - Neuzil, Jiri - Ikawa, Masahito - Erickson, Kent - Lam, Kit S. - Moore, Harry - Komrskova, Katerina
PY - 2022
TI - MAIA; Fc receptor-like 3; supersedes JUNO as IZUMO1 receptor during human fertilization
JF - Science advances
VL - 8
IS - 36
SP - 1-16
EP - 1-16
PB - American Association for the Advancement of Science
SN - 23752548
KW - human fertilization
KW - MAIA
KW - Fc receptor-like 3
KW - supersedes JUNO
KW - IZUMO1
UR - https://www.science.org/doi/10.1126/sciadv.abn0047
N2 - Gamete fusion is a critical event of mammalian fertilization. A random one-bead one-compound combinatorial peptide library represented synthetic human egg mimics and identified a previously unidentified ligand as Fc receptor-like 3, named MAIA after the mythological goddess intertwined with JUNO. This immunoglobulin super family receptor was expressed on human oolemma and played a major role during sperm-egg adhesion and fusion. MAIA forms a highly stable interaction with the known IZUMO1/JUNO sperm-egg complex, permitting specific gamete fusion. The complexity of the MAIA isotype may offer a cryptic sexual selection mechanism to avoid genetic incompatibility and achieve favorable fitness outcomes.
ER -
VONDRAKOVA, Jana, Michaela FROLIKOVA, Lukas DED, Jiri CERNY, Pavla POSTLEROVA, Veronika PALENIKOVA, Ondrej SIMONIK, Zuzana NAHACKA, Krystof BASUS, Eliska VALASKOVA, Radek MACHAN, Allan PACEY, Zuzana HOLUBCOVÁ, Pavel KOUBEK, Zuzana EZROVA, Soojin PARK, Ruiwu LIU, Raghavendran PARTHA, Nathan CLARK, Jiri NEUZIL, Masahito IKAWA, Kent ERICKSON, Kit S. LAM, Harry MOORE a Katerina KOMRSKOVA. MAIA; Fc receptor-like 3; supersedes JUNO as IZUMO1 receptor during human fertilization. \textit{Science advances}. WASHINGTON: American Association for the Advancement of Science, 2022, roč.~8, č.~36, s.~1-16. ISSN~2375-2548. Dostupné z: https://dx.doi.org/10.1126/sciadv.abn0047.
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