Making the head: Caspases in life and death

J 2023

Making the head: Caspases in life and death

ŠVANDOVÁ, Eva, Herve LESOT, Paul SHARPE and Eva MATALOVA

Basic information

Original name

Making the head: Caspases in life and death

Authors

ŠVANDOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Herve LESOT, Paul SHARPE and Eva MATALOVA

Edition

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Lausanne, FRONTIERS MEDIA SA, 2023, 2296-634X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10601 Cell biology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.500 in 2022

RIV identification code

RIV/00216224:14110/23:00134074

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3389/fcell.2022.1075751

UT WoS

000920367200001

Keywords in English

caspases; development; head; apoptotic; non-apoptotic

Abstract

V originále

The term apoptosis, as a way of programmed cell death, was coined a half century ago and since its discovery the process has been extensively investigated. The anatomy and physiology of the head are complex and thus apoptosis has mostly been followed in separate structures, tissues or cell types. This review aims to provide a comprehensive overview of recent knowledge concerning apoptosis-related molecules involved in the development of structures of head with a particular focus on caspases, cysteine proteases having a key position in apoptotic pathways. Since many classical apoptosis-related molecules, including caspases, are emerging in several non-apoptotic processes, these were also considered. The largest organ of the head region is the brain and its development has been extensively investigated, including the roles of apoptosis and related molecules. Neurogenesis research also includes sensory organs such as the eye and ear, efferent nervous system and associated muscles and glands. Caspases have been also associated with normal function of the skin and hair follicles. Regarding mineralised tissues within craniofacial morphogenesis, apoptosis in bones has been of interest along with palate fusion and tooth development. Finally, the role of apoptosis and caspases in angiogenesis, necessary for any tissue/organ development and maintenance/homeostasis, are discussed. Additionally, this review points to abnormalities of development resulting from improper expression/activation of apoptosis-related molecules.

Links

GA21-21409S, research and development project

Name: Fyziologické vlastnosti a funkce kmenových buněk vztahujících se k dentici se zaměřením na kontext in vivo

Investor: Czech Science Foundation

Citovat

ŠVANDOVÁ, Eva, Herve LESOT, Paul SHARPE and Eva MATALOVA. Making the head: Caspases in life and death. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Lausanne: FRONTIERS MEDIA SA, 2023, vol. 10, January 2023, p. 1-17. ISSN 2296-634X. Available from: https://dx.doi.org/10.3389/fcell.2022.1075751.

@article{2262220,
   author = {Švandová, Eva and Lesot, Herve and Sharpe, Paul and Matalova, Eva},
   article_location = {Lausanne},
   article_number = {January 2023},
   doi = {http://dx.doi.org/10.3389/fcell.2022.1075751},
   keywords = {caspases; development; head; apoptotic; non-apoptotic},
   language = {eng},
   issn = {2296-634X},
   journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
   title = {Making the head: Caspases in life and death},
   url = {https://www.frontiersin.org/articles/10.3389/fcell.2022.1075751/full},
   volume = {10},
   year = {2023}
}

TY  - JOUR
ID  - 2262220
AU  - Švandová, Eva - Lesot, Herve - Sharpe, Paul - Matalova, Eva
PY  - 2023
TI  - Making the head: Caspases in life and death
JF  - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
VL  - 10
IS  - January 2023
SP  - 1-17
EP  - 1-17
PB  - FRONTIERS MEDIA SA
SN  - 2296634X
KW  - caspases
KW  - development
KW  - head
KW  - apoptotic
KW  - non-apoptotic
UR  - https://www.frontiersin.org/articles/10.3389/fcell.2022.1075751/full
N2  - The term apoptosis, as a way of programmed cell death, was coined a half century ago and since its discovery the process has been extensively investigated. The anatomy and physiology of the head are complex and thus apoptosis has mostly been followed in separate structures, tissues or cell types. This review aims to provide a comprehensive overview of recent knowledge concerning apoptosis-related molecules involved in the development of structures of head with a particular focus on caspases, cysteine proteases having a key position in apoptotic pathways. Since many classical apoptosis-related molecules, including caspases, are emerging in several non-apoptotic processes, these were also considered. The largest organ of the head region is the brain and its development has been extensively investigated, including the roles of apoptosis and related molecules. Neurogenesis research also includes sensory organs such as the eye and ear, efferent nervous system and associated muscles and glands. Caspases have been also associated with normal function of the skin and hair follicles. Regarding mineralised tissues within craniofacial morphogenesis, apoptosis in bones has been of interest along with palate fusion and tooth development. Finally, the role of apoptosis and caspases in angiogenesis, necessary for any tissue/organ development and maintenance/homeostasis, are discussed. Additionally, this review points to abnormalities of development resulting from improper expression/activation of apoptosis-related molecules.
ER  -

ŠVANDOVÁ, Eva, Herve LESOT, Paul SHARPE and Eva MATALOVA. Making the head: Caspases in life and death. \textit{FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY}. Lausanne: FRONTIERS MEDIA SA, 2023, vol.~10, January 2023, p.~1-17. ISSN~2296-634X. Available from: https://dx.doi.org/10.3389/fcell.2022.1075751.

Detailed Information on Publication Record