In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia
eupatoria L. Shows Antibacterial Activity

J 2023

In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity

BALAZOVA, Ludmila, Tomáš WOLASCHKA, Simona ROHAĽOVÁ, Nina DANEU, Martin STAHORSKY et. al.

Základní údaje

Originální název

In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity

Autoři

BALAZOVA, Ludmila (garant), Tomáš WOLASCHKA (703 Slovensko), Simona ROHAĽOVÁ (703 Slovensko, domácí), Nina DANEU, Martin STAHORSKY, Aneta SALAYOVA, Ludmila TKACIKOVA a Jarmila EFTIMOVA

Vydání

LIFE-BASEL, BASEL, MDPI, 2023, 2075-1729

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.200 v roce 2022

Kód RIV

RIV/00216224:14160/23:00130503

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.3390/life13020573

UT WoS

000941440700001

Klíčová slova anglicky

nanoparticles; silver; Agrimonia eupatoria; in situ gel

Štítky

rivok, ÚFT

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 29. 2. 2024 09:11, Mgr. Daniela Černá

Anotace

V originále

Silver nanoparticles (Ag NPs) with antibacterial activity can be prepared in different ways. In our case, we used ecological green synthesis with Agrimonia eupatoria L. The plant extract was used with Ag NPs for the first time to prepare termosensitive in situ gels (ISGs). Such gels are used to heal human or animal skin and mucous membranes, as they can change from a liquid to solid state after application. Ag NPs were characterized with various techniques (FTIR, TEM, size distribution, zeta potential) and their antibacterial activity was tested against Staphylococcus aureus and Escherichia coli. In accordance with the TEM data, we prepared monodispersed spherical Ag NPs with an average size of about 20 nm. Organic active compounds from Agrimonia eupatoria L. were found on their surfaces using FTIR spectroscopy. Surprisingly, only the in situ gel with Ag NPs showed antibacterial activity against Escherichia coli, while Ag NPs alone did not. Ag NPs prepared via green synthesis using plants with medicinal properties and incorporated into ISGs have great potential for wound healing due to the antibacterial activity of Ag NPs and the dermatological activity of organic substances from plants.

Citovat

BALAZOVA, Ludmila, Tomáš WOLASCHKA, Simona ROHAĽOVÁ, Nina DANEU, Martin STAHORSKY, Aneta SALAYOVA, Ludmila TKACIKOVA a Jarmila EFTIMOVA. In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity. LIFE-BASEL. BASEL: MDPI, 2023, roč. 13, č. 2, s. 1-20. ISSN 2075-1729. Dostupné z: https://dx.doi.org/10.3390/life13020573.

@article{2270557,
   author = {Balazova, Ludmila and Wolaschka, Tomáš and Rohaľová, Simona and Daneu, Nina and Stahorsky, Martin and Salayova, Aneta and Tkacikova, Ludmila and Eftimova, Jarmila},
   article_location = {BASEL},
   article_number = {2},
   doi = {http://dx.doi.org/10.3390/life13020573},
   keywords = {nanoparticles; silver; Agrimonia eupatoria; in situ gel},
   language = {eng},
   issn = {2075-1729},
   journal = {LIFE-BASEL},
   title = {In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity},
   url = {https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955},
   volume = {13},
   year = {2023}
}

TY  - JOUR
ID  - 2270557
AU  - Balazova, Ludmila - Wolaschka, Tomáš - Rohaľová, Simona - Daneu, Nina - Stahorsky, Martin - Salayova, Aneta - Tkacikova, Ludmila - Eftimova, Jarmila
PY  - 2023
TI  - In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity
JF  - LIFE-BASEL
VL  - 13
IS  - 2
SP  - 1-20
EP  - 1-20
PB  - MDPI
SN  - 20751729
KW  - nanoparticles
KW  - silver
KW  - Agrimonia eupatoria
KW  - in situ gel
UR  - https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955
N2  - Silver nanoparticles (Ag NPs) with antibacterial activity can be prepared in different ways. In our case, we used ecological green synthesis with Agrimonia eupatoria L. The plant extract was used with Ag NPs for the first time to prepare termosensitive in situ gels (ISGs). Such gels are used to heal human or animal skin and mucous membranes, as they can change from a liquid to solid state after application. Ag NPs were characterized with various techniques (FTIR, TEM, size distribution, zeta potential) and their antibacterial activity was tested against Staphylococcus aureus and Escherichia coli. In accordance with the TEM data, we prepared monodispersed spherical Ag NPs with an average size of about 20 nm. Organic active compounds from Agrimonia eupatoria L. were found on their surfaces using FTIR spectroscopy. Surprisingly, only the in situ gel with Ag NPs showed antibacterial activity against Escherichia coli, while Ag NPs alone did not. Ag NPs prepared via green synthesis using plants with medicinal properties and incorporated into ISGs have great potential for wound healing due to the antibacterial activity of Ag NPs and the dermatological activity of organic substances from plants.
ER  -

BALAZOVA, Ludmila, Tomáš WOLASCHKA, Simona ROHAĽOVÁ, Nina DANEU, Martin STAHORSKY, Aneta SALAYOVA, Ludmila TKACIKOVA a Jarmila EFTIMOVA. In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity. \textit{LIFE-BASEL}. BASEL: MDPI, 2023, roč.~13, č.~2, s.~1-20. ISSN~2075-1729. Dostupné z: https://dx.doi.org/10.3390/life13020573.

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