MARCINIAK, Jacek, Jana HURYCHOVÁ, Sara ŠREIBR, Pavel HYRŠL and Pavel DOBEŠ. ROLE OF ASCORBIC ACID AND OTHER ANTIOXIDANTS IN HONEY BEE RESISTANCE AND LONGEVITY. In BeeConnected 2023. 2023. ISBN 978-80-11-03089-6.
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Basic information
Original name ROLE OF ASCORBIC ACID AND OTHER ANTIOXIDANTS IN HONEY BEE RESISTANCE AND LONGEVITY
Name in Czech ROLE OF ASCORBIC ACID AND OTHER ANTIOXIDANTS IN HONEY BEE RESISTANCE AND LONGEVITY
Authors MARCINIAK, Jacek (203 Czech Republic, guarantor, belonging to the institution), Jana HURYCHOVÁ (203 Czech Republic, belonging to the institution), Sara ŠREIBR (276 Germany, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution) and Pavel DOBEŠ (203 Czech Republic, belonging to the institution).
Edition BeeConnected 2023, 2023.
Other information
Original language English
Type of outcome Presentations at conferences
Field of Study 10616 Entomology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/23:00133964
Organization unit Faculty of Science
ISBN 978-80-11-03089-6
Keywords (in Czech) Apis mellifera; kyselina askorbová; antioxidanty; imunita; dlouhověkost
Keywords in English Apis mellifera; ascorbic acid; antioxidants; immunity; longevity
Tags International impact
Changed by Changed by: Mgr. Jacek Marciniak, učo 450943. Changed: 5/4/2024 22:57.
Abstract
Considering substantial differences in the lifespan of genetically similar individuals, honey bees are an exquisite model organism for longevity research. One of the prevalent theories in this field is the free-radical theory of aging. It proposes that reactive oxygen species (ROS) of endogenous (oxidative metabolism) and exogenous (intake of pollutants, radiation, etc.) origin cause damage to biological macromolecules, which accumulates over time and causes senescence and aging-associated diseases1,2. According to this theory, more effective protection against ROS leads to a longer lifespan, suggesting that bees of varying lifespans differ in their antioxidant system. We aim to gain a deeper understanding of the honey bee redox system and mechanisms participating in the resistance and longevity of winter bees. To identify components of the bee redox system undergoing significant seasonal changes, we have collected honey bee samples monthly since February 2021. Our results so far showed no significant difference in total antioxidant capacity throughout the seasons but suggested changes in its underlying mechanism. For example, levels of non-enzymatic antioxidants such as glutathione and ascorbic acid fluctuated seasonally, with peaks in months of high brood-rearing activity. Ascorbic acid is especially interesting since it can be detected in bee products, and some studies suggest the positive effect of its supplementation on longevity and immunity3. However, some questions about ascorbic acid in honey bees remain unanswered. For example, it is still unclear whether bees or their microbiota are capable of its synthesis and, if so, how significant it is compared to dietary sources. To answer these questions, we will quantify ascorbic acid using electron paramagnetic resonance spectroscopy in different bee-related samples (honey, pollen, hemolymph, etc.). Our research is supported by The Ministry of Agriculture of the Czech Republic (QK1910286, QK21010088).
Abstract (in Czech)
Considering substantial differences in the lifespan of genetically similar individuals, honey bees are an exquisite model organism for longevity research. One of the prevalent theories in this field is the free-radical theory of aging. It proposes that reactive oxygen species (ROS) of endogenous (oxidative metabolism) and exogenous (intake of pollutants, radiation, etc.) origin cause damage to biological macromolecules, which accumulates over time and causes senescence and aging-associated diseases1,2. According to this theory, more effective protection against ROS leads to a longer lifespan, suggesting that bees of varying lifespans differ in their antioxidant system. We aim to gain a deeper understanding of the honey bee redox system and mechanisms participating in the resistance and longevity of winter bees. To identify components of the bee redox system undergoing significant seasonal changes, we have collected honey bee samples monthly since February 2021. Our results so far showed no significant difference in total antioxidant capacity throughout the seasons but suggested changes in its underlying mechanism. For example, levels of non-enzymatic antioxidants such as glutathione and ascorbic acid fluctuated seasonally, with peaks in months of high brood-rearing activity. Ascorbic acid is especially interesting since it can be detected in bee products, and some studies suggest the positive effect of its supplementation on longevity and immunity3. However, some questions about ascorbic acid in honey bees remain unanswered. For example, it is still unclear whether bees or their microbiota are capable of its synthesis and, if so, how significant it is compared to dietary sources. To answer these questions, we will quantify ascorbic acid using electron paramagnetic resonance spectroscopy in different bee-related samples (honey, pollen, hemolymph, etc.). Our research is supported by The Ministry of Agriculture of the Czech Republic (QK1910286, QK21010088).
Links
QK1910286, research and development projectName: Efektivní postupy a strategie pro zvládání včelích chorob a udržitelný chov včelstev
Investor: Ministry of Agriculture of the CR
QK21010088, research and development projectName: Vývoj prostředku na podporu včelí imunity na bázi probiotik, spolu s technologií jeho výroby a potravinářským využitím vedlejšího produktu
Investor: Ministry of Agriculture of the CR
PrintDisplayed: 26/7/2024 06:21