Are there differences in EEG between epileptic patients with
vagal nerve stimulation (VNS) and healthy controls?

a 2022

Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?

DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, J. CHLADEK, Tereza JURKOVÁ, Jan CHRASTINA et. al.

Základní údaje

Originální název

Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?

Autoři

DOLEŽALOVÁ, Irena (203 Česká republika, domácí), Eva KORIŤÁKOVÁ (203 Česká republika, domácí), J. CHLADEK (203 Česká republika), Tereza JURKOVÁ (203 Česká republika, domácí), Jan CHRASTINA (203 Česká republika, domácí), P. JURAK (203 Česká republika) a Milan BRÁZDIL (203 Česká republika, domácí)

Vydání

8th Congress of the European-Academy-of-Neurology (EAN), 2022

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.100

Kód RIV

RIV/00216224:14110/22:00129747

Organizační jednotka

Lékařská fakulta

ISSN

UT WoS

000815254002300

Klíčová slova anglicky

EEG; epileptic patients; vagal nerve stimulation

Štítky

rivok

Příznaky

Mezinárodní význam

Změněno: 24. 4. 2023 15:45, Mgr. Tereza Miškechová

Anotace

V originále

Background and aims: The presented work is based on the results of our published work, in which we focused on the VNS efficacy prediction in patients with drug-resistant epilepsy. We found that there are differences in power spectra between VNS responders and non-responders. We asked two more questions. Are there differences between the epileptic patients with VNS and healthy controls? Do the EEG power spectra in healthy controls resemble more responders or non-responders to VNS therapy? Methods: We identified retrospectively EEG recording in epileptic patients with VNS and in healthy controls. The epileptic patients were classified based on the VNS efficacy as responder and non-responders EEG was segmented into several time-intervals (resting-state, eyes-opening 1, resting state, photic stimulation, hyperventilation, eyes opening 2, resting state 3 and resting state) and frequency bands. Subsequently, we established relative EEG power spectra in pre-defined frequency bands and time-intervals. Results: We identified EEG in 56 healthy controls and in 60 epileptic patients with VNS (35 responders, 25 non-responders). When compared healthy controls and epileptic patients, we identified EEG power spectra differences in theta (eyes-opening 1, 2), alpha (eyes-opening 1,2) and beta frequency range (eyes-opening 1). When compared responders to VNS therapy and healthy controls, we found more significant differences than in non-responders.

Návaznosti

NV19-04-00343, projekt VaV

Název: Predikce Efektu Stimulace u pacientů s Epilepsií (PRESEnCE) (Akronym: PRESEnCE)

Investor: Ministerstvo zdravotnictví ČR, Prediction of Stimulation Efficacy in Epilepsy

Citovat

DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, J. CHLADEK, Tereza JURKOVÁ, Jan CHRASTINA, P. JURAK a Milan BRÁZDIL. Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? In 8th Congress of the European-Academy-of-Neurology (EAN). 2022. ISSN 1351-5101.

@proceedings{2277437,
   author = {Doležalová, Irena and Koriťáková, Eva and Chladek, J. and Jurková, Tereza and Chrastina, Jan and Jurak, P. and Brázdil, Milan},
   booktitle = {8th Congress of the European-Academy-of-Neurology (EAN)},
   keywords = {EEG; epileptic patients; vagal nerve stimulation},
   language = {eng},
   title = {Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?},
   url = {https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466},
   year = {2022}
}

TY  - CONF
ID  - 2277437
AU  - Doležalová, Irena - Koriťáková, Eva - Chladek, J. - Jurková, Tereza - Chrastina, Jan - Jurak, P. - Brázdil, Milan
PY  - 2022
TI  - Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?
KW  - EEG
KW  - epileptic patients
KW  - vagal nerve stimulation
UR  - https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466
N2  - Background and aims: The presented work is based on the results of our published work, in which we focused on the VNS efficacy prediction in patients with drug-resistant epilepsy. We found that there are differences in power spectra between VNS responders and non-responders. We asked two more questions. Are there differences between the epileptic patients with VNS and healthy controls? Do the EEG power spectra in healthy controls resemble more responders or non-responders to VNS therapy? Methods: We identified retrospectively EEG recording in epileptic patients with VNS and in healthy controls. The epileptic patients were classified based on the VNS efficacy as responder and non-responders EEG was segmented into several time-intervals (resting-state, eyes-opening 1, resting state, photic stimulation, hyperventilation, eyes opening 2, resting state 3 and resting state) and frequency bands. Subsequently, we established relative EEG power spectra in pre-defined frequency bands and time-intervals. Results: We identified EEG in 56 healthy controls and in 60 epileptic patients with VNS (35 responders, 25 non-responders). When compared healthy controls and epileptic patients, we identified EEG power spectra differences in theta (eyes-opening 1, 2), alpha (eyes-opening 1,2) and beta frequency range (eyes-opening 1). When compared responders to VNS therapy and healthy controls, we found more significant differences than in non-responders.
ER  -

DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, J. CHLADEK, Tereza JURKOVÁ, Jan CHRASTINA, P. JURAK a Milan BRÁZDIL. Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? In \textit{8th Congress of the European-Academy-of-Neurology (EAN)}. 2022. ISSN~1351-5101.

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