| GIUSEPPE, De Luca, Stephane MANZO-SILBERMAN, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Oliver BUSLJETIK, Miha CERCEK, Lisette OKKELS, Poay Huan LOH, Lucian CALMAC, Roura i Ferrer GERARD, Alexandre QUADROS, Marek MILEWSKI, di Uccio Fortunato SCOTTO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Aaron Wong Sung LUNG, Petr KALA, Jose Luis Diez GIL, Xavier CARRILLO, Maurits DIRKSEN, Victor BECERRA, Michael Kang-yin LEE, Dafsah Arifa JUZAR, Rodrigo de Moura JOAQUIM, Roberto PALADINO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Lux ARPAD, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Kadir Ugur MERT, Flores Rios XACOBE, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Francisco Bosa OJEDA, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Juan Sanchis FORES, Luigi VIGNALI, Helder PEREIRA, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, Joao Antonio Brum SILVEIRA, Cesar Rodrigo ZONI, Ivan BESSONOV, Giuseppe UCCELLO, George KOCHIADAKIS, Dimitrios ALEXOPULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Alejandro Gutierrez BARRIOS, Juan Pablo BACHINI, Alex ROCHA, Frankie C C TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Veauthyelau SAINT-JOY, Gustavo PESSAH, Andrea TUCCILLO, Alfonso IELASI, Giuliana CORTESE, Guido PARODI, Mohamed Abed BOURAGHDA, Marcia MOURA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA, Matteo NARDIN a Monica VERDOIA. Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. Journal of Clinical Medicine. BASEL: MDPI, 2023, roč. 12, č. 3, s. 1-15. ISSN 2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm12030896. |
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@article{2279478,
author = {Giuseppe, De Luca and ManzoandSilberman, Stephane and Algowhary, Magdy and Uguz, Berat and Oliveira, Dinaldo C and Ganyukov, Vladimir and Busljetik, Oliver and Cercek, Miha and Okkels, Lisette and Loh, Poay Huan and Calmac, Lucian and Gerard, Roura i Ferrer and Quadros, Alexandre and Milewski, Marek and Scotto, di Uccio Fortunato and Clemens, von Birgelen and Versaci, Francesco and Jurrien, Ten Berg and Casella, Gianni and Lung, Aaron Wong Sung and Kala, Petr and Gil, Jose Luis Diez and Carrillo, Xavier and Dirksen, Maurits and Becerra, Victor and Lee, Michael Kangandyin and Juzar, Dafsah Arifa and Joaquim, Rodrigo de Moura and Paladino, Roberto and Milicic, Davor and Davlouros, Periklis and Bakraceski, Nikola and Zilio, Filippo and Donazzan, Luca and Kraaijeveld, Adriaan and Galasso, Gennaro and Arpad, Lux and Marinucci, Lucia and Guiducci, Vincenzo and Menichelli, Maurizio and Scoccia, Alessandra and Yamac, Aylin Hatice and Mert, Kadir Ugur and Xacobe, Flores Rios and Kovarnik, Tomas and Kidawa, Michal and Moreu, Jose and Flavien, Vincent and Fabris, Enrico and MartinezandLuengas, Inigo Lozano and Boccalatte, Marco and Ojeda, Francisco Bosa and ArellanoandSerrano, Carlos and Caiazzo, Gianluca and Cirrincione, Giuseppe and Kao, HsienandLi and Fores, Juan Sanchis and Vignali, Luigi and Pereira, Helder and Ordonez, Santiago and Ozkan, Alev Arat and Scheller, Bruno and Lehtola, Heidi and Teles, Rui and Mantis, Christos and Antti, Ylitalo and Silveira, Joao Antonio Brum and Zoni, Cesar Rodrigo and Bessonov, Ivan and Uccello, Giuseppe and Kochiadakis, George and Alexopulos, Dimitrios and Uribe, Carlos E and Kanakakis, John and Faurie, Benjamin and Gabrielli, Gabriele and Barrios, Alejandro Gutierrez and Bachini, Juan Pablo and Rocha, Alex and Tam, Frankie C C and Rodriguez, Alfredo and Lukito, Antonia Anna and SaintandJoy, Veauthyelau and Pessah, Gustavo and Tuccillo, Andrea and Ielasi, Alfonso and Cortese, Giuliana and Parodi, Guido and Bouraghda, Mohamed Abed and Moura, Marcia and Kedhi, Elvin and Lamelas, Pablo and Suryapranata, Harry and Nardin, Matteo and Verdoia, Monica},
article_location = {BASEL},
article_number = {3},
doi = {http://dx.doi.org/10.3390/jcm12030896},
keywords = {gender; ST-segment elevation myocardial infarction; percutaneous coronary intervention; COVID-19},
language = {eng},
issn = {2077-0383},
journal = {Journal of Clinical Medicine},
title = {Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry},
url = {https://www.mdpi.com/2077-0383/12/3/896},
volume = {12},
year = {2023}
}
TY - JOUR
ID - 2279478
AU - Giuseppe, De Luca - Manzo-Silberman, Stephane - Algowhary, Magdy - Uguz, Berat - Oliveira, Dinaldo C - Ganyukov, Vladimir - Busljetik, Oliver - Cercek, Miha - Okkels, Lisette - Loh, Poay Huan - Calmac, Lucian - Gerard, Roura i Ferrer - Quadros, Alexandre - Milewski, Marek - Scotto, di Uccio Fortunato - Clemens, von Birgelen - Versaci, Francesco - Jurrien, Ten Berg - Casella, Gianni - Lung, Aaron Wong Sung - Kala, Petr - Gil, Jose Luis Diez - Carrillo, Xavier - Dirksen, Maurits - Becerra, Victor - Lee, Michael Kang-yin - Juzar, Dafsah Arifa - Joaquim, Rodrigo de Moura - Paladino, Roberto - Milicic, Davor - Davlouros, Periklis - Bakraceski, Nikola - Zilio, Filippo - Donazzan, Luca - Kraaijeveld, Adriaan - Galasso, Gennaro - Arpad, Lux - Marinucci, Lucia - Guiducci, Vincenzo - Menichelli, Maurizio - Scoccia, Alessandra - Yamac, Aylin Hatice - Mert, Kadir Ugur - Xacobe, Flores Rios - Kovarnik, Tomas - Kidawa, Michal - Moreu, Jose - Flavien, Vincent - Fabris, Enrico - Martinez-Luengas, Inigo Lozano - Boccalatte, Marco - Ojeda, Francisco Bosa - Arellano-Serrano, Carlos - Caiazzo, Gianluca - Cirrincione, Giuseppe - Kao, Hsien-Li - Fores, Juan Sanchis - Vignali, Luigi - Pereira, Helder - Ordonez, Santiago - Ozkan, Alev Arat - Scheller, Bruno - Lehtola, Heidi - Teles, Rui - Mantis, Christos - Antti, Ylitalo - Silveira, Joao Antonio Brum - Zoni, Cesar Rodrigo - Bessonov, Ivan - Uccello, Giuseppe - Kochiadakis, George - Alexopulos, Dimitrios - Uribe, Carlos E - Kanakakis, John - Faurie, Benjamin - Gabrielli, Gabriele - Barrios, Alejandro Gutierrez - Bachini, Juan Pablo - Rocha, Alex - Tam, Frankie C C - Rodriguez, Alfredo - Lukito, Antonia Anna - Saint-Joy, Veauthyelau - Pessah, Gustavo - Tuccillo, Andrea - Ielasi, Alfonso - Cortese, Giuliana - Parodi, Guido - Bouraghda, Mohamed Abed - Moura, Marcia - Kedhi, Elvin - Lamelas, Pablo - Suryapranata, Harry - Nardin, Matteo - Verdoia, Monica
PY - 2023
TI - Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
JF - Journal of Clinical Medicine
VL - 12
IS - 3
SP - 1-15
EP - 1-15
PB - MDPI
SN - 20770383
KW - gender
KW - ST-segment elevation myocardial infarction
KW - percutaneous coronary intervention
KW - COVID-19
UR - https://www.mdpi.com/2077-0383/12/3/896
N2 - Background. Several reports have demonstrated the impact of the COVID-19 pandemic on the management and outcome of patients with ST-segment elevation myocardial infarction (STEMI). The aim of the current analysis is to investigate the potential gender difference in the effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI patients within the ISACS-STEMI COVID-19 Registry. Methods. This retrospective multicenter registry was performed in high-volume primary percutaneous coronary intervention (PPCI) centers on four continents and included STEMI patients undergoing PPCIs in March-June 2019 and 2020. Patients were divided according to gender. The main outcomes were the incidence and timing of the PPCI, (ischemia time >= 12 h and door-to-balloon >= 30 min) and in-hospital or 30-day mortality. Results. We included 16683 STEMI patients undergoing PPCIs in 109 centers. In 2020 during the pandemic, there was a significant reduction in PPCIs compared to 2019 (IRR 0.843 (95% CI: 0.825-0.861, p < 0.0001). We did not find a significant gender difference in the effects of the COVID-19 pandemic on the numbers of STEMI patients, which were similarly reduced from 2019 to 2020 in both groups, or in the mortality rates. Compared to prepandemia, 30-day mortality was significantly higher during the pandemic period among female (12.1% vs. 8.7%; adjusted HR [95% CI] = 1.66 [1.31-2.11], p < 0.001) but not male patients (5.8% vs. 6.7%; adjusted HR [95% CI] = 1.14 [0.96-1.34], p = 0.12). Conclusions. The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures similarly observed in both genders. Furthermore, we observed significantly increased in-hospital and 30-day mortality rates during the pandemic only among females. Trial registration number: NCT 04412655.
ER -
GIUSEPPE, De Luca, Stephane MANZO-SILBERMAN, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Oliver BUSLJETIK, Miha CERCEK, Lisette OKKELS, Poay Huan LOH, Lucian CALMAC, Roura i Ferrer GERARD, Alexandre QUADROS, Marek MILEWSKI, di Uccio Fortunato SCOTTO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Aaron Wong Sung LUNG, Petr KALA, Jose Luis Diez GIL, Xavier CARRILLO, Maurits DIRKSEN, Victor BECERRA, Michael Kang-yin LEE, Dafsah Arifa JUZAR, Rodrigo de Moura JOAQUIM, Roberto PALADINO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Lux ARPAD, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Kadir Ugur MERT, Flores Rios XACOBE, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Francisco Bosa OJEDA, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Juan Sanchis FORES, Luigi VIGNALI, Helder PEREIRA, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, Joao Antonio Brum SILVEIRA, Cesar Rodrigo ZONI, Ivan BESSONOV, Giuseppe UCCELLO, George KOCHIADAKIS, Dimitrios ALEXOPULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Alejandro Gutierrez BARRIOS, Juan Pablo BACHINI, Alex ROCHA, Frankie C C TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Veauthyelau SAINT-JOY, Gustavo PESSAH, Andrea TUCCILLO, Alfonso IELASI, Giuliana CORTESE, Guido PARODI, Mohamed Abed BOURAGHDA, Marcia MOURA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA, Matteo NARDIN a Monica VERDOIA. Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. \textit{Journal of Clinical Medicine}. BASEL: MDPI, 2023, roč.~12, č.~3, s.~1-15. ISSN~2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm12030896.
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