Common xanthene fluorescent dyes are visible-light activatable
CO-releasing molecules

J 2023

Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules

MARTÍNEK, Marek; Lucie LUDVÍKOVÁ; Mária ŠRANKOVÁ; Rafael NAVRÁTIL; Lucie MUCHOVÁ et al.

Základní údaje

Originální název

Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules

Autoři

MARTÍNEK, Marek; Lucie LUDVÍKOVÁ; Mária ŠRANKOVÁ; Rafael NAVRÁTIL; Lucie MUCHOVÁ; Jiří HUZLÍK; Libor VÍTEK; Petr KLÁN a Peter ŠEBEJ

Vydání

Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2023, 1477-0520

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10401 Organic chemistry

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.900

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/23:00130825

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

CARBON-MONOXIDE; QUANTUM YIELD; EOSIN-Y; PHOTOCHEMISTRY; OXYGEN; PHOTODEGRADATION; ANGIOGRAPHY; MECHANISM

Štítky

14313010, 143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 17. 6. 2025 09:19, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

Fluorescein, eosin Y, and rose bengal are dyes used in clinical medicine and considered (photo-)chemically stable. Upon extensive irradiation with visible light in aqueous solutions, we found that these compounds release carbon monoxide (CO) - a bioactive gasotransmitter - in 40-100% yields along with the production of low-mass secondary photoproducts, such as phthalic and formic acids, in a multistep degradation process. Such photochemistry should be considered in applications of these dyes, and they could also be utilized as visible-light activatable CO-releasing molecules (photoCORMs) with biological implications.

Návaznosti

EF17_043/0009632, projekt VaV

Název: CETOCOEN Excellence

GJ20-30004Y, projekt VaV

Název: Nové strukturní motivy pro rozšíření možností lineárních polymethinových barviv

Investor: Grantová agentura ČR, Nové strukturní motivy pro rozšíření možností lineárních polymethinových barviv

857560, interní kód MU
(Kód CEP: EF17_043/0009632)

Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)

Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation

90121, velká výzkumná infrastruktura

Název: RECETOX RI

Citovat

MARTÍNEK, Marek; Lucie LUDVÍKOVÁ; Mária ŠRANKOVÁ; Rafael NAVRÁTIL; Lucie MUCHOVÁ; Jiří HUZLÍK; Libor VÍTEK; Petr KLÁN a Peter ŠEBEJ. Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules. Organic and Biomolecular Chemistry. Royal Society of Chemistry, 2023, roč. 21, č. 1, s. 93-97. ISSN 1477-0520. Dostupné z: https://doi.org/10.1039/d2ob01823c.

@article{2285197,
   author = {Martínek, Marek and Ludvíková, Lucie and Šranková, Mária and Navrátil, Rafael and Muchová, Lucie and Huzlík, Jiří and Vítek, Libor and Klán, Petr and Šebej, Peter},
   article_number = {1},
   doi = {https://doi.org/10.1039/d2ob01823c},
   keywords = {CARBON-MONOXIDE; QUANTUM YIELD; EOSIN-Y; PHOTOCHEMISTRY; OXYGEN; PHOTODEGRADATION; ANGIOGRAPHY; MECHANISM},
   language = {eng},
   issn = {1477-0520},
   journal = {Organic and Biomolecular Chemistry},
   title = {Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules},
   url = {https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB01823C},
   volume = {21},
   year = {2023}
}

TY  - JOUR
ID  - 2285197
AU  - Martínek, Marek - Ludvíková, Lucie - Šranková, Mária - Navrátil, Rafael - Muchová, Lucie - Huzlík, Jiří - Vítek, Libor - Klán, Petr - Šebej, Peter
PY  - 2023
TI  - Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules
JF  - Organic and Biomolecular Chemistry
VL  - 21
IS  - 1
SP  - 93-97
EP  - 93-97
PB  - Royal Society of Chemistry
SN  - 14770520
KW  - CARBON-MONOXIDE
KW  - QUANTUM YIELD
KW  - EOSIN-Y
KW  - PHOTOCHEMISTRY
KW  - OXYGEN
KW  - PHOTODEGRADATION
KW  - ANGIOGRAPHY
KW  - MECHANISM
UR  - https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB01823C
N2  - Fluorescein, eosin Y, and rose bengal are dyes used in clinical medicine and considered (photo-)chemically stable. Upon extensive irradiation with visible light in aqueous solutions, we found that these compounds release carbon monoxide (CO) - a bioactive gasotransmitter - in 40-100% yields along with the production of low-mass secondary photoproducts, such as phthalic and formic acids, in a multistep degradation process. Such photochemistry should be considered in applications of these dyes, and they could also be utilized as visible-light activatable CO-releasing molecules (photoCORMs) with biological implications.
ER  -

MARTÍNEK, Marek; Lucie LUDVÍKOVÁ; Mária ŠRANKOVÁ; Rafael NAVRÁTIL; Lucie MUCHOVÁ; Jiří HUZLÍK; Libor VÍTEK; Petr KLÁN a Peter ŠEBEJ. Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules. \textit{Organic and Biomolecular Chemistry}. Royal Society of Chemistry, 2023, roč.~21, č.~1, s.~93-97. ISSN~1477-0520. Dostupné z: https://doi.org/10.1039/d2ob01823c.

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