Long-Term Follow-Up of Patients Needing Extracorporeal Membrane
Oxygenation Following a Critical Course of COVID-19

J 2023

Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19

GENZOR, Samuel; Pavol POBEHA; Martin SIMEK; Petr JAKUBEC; Jan MIZERA et al.

Základní údaje

Originální název

Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19

Autoři

GENZOR, Samuel; Pavol POBEHA; Martin SIMEK; Petr JAKUBEC; Jan MIZERA; Martin VYKOPAL; Milan SOVA; Jakub VANEK a Jan PRASKO

Vydání

LIFE-BASEL, BASEL, MDPI, 2023, 2075-1729

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.200

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/23:00131203

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

ECMO; COVID-19; long-term outcome

Štítky

14110215, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 7. 2023 10:19, Mgr. Tereza Miškechová

Anotace

V originále

Introduction: Severe respiratory failure is one of the most serious complications of coronavirus disease 2019 (COVID-19). In a small proportion of patients, mechanical ventilation fails to provide adequate oxygenation and extracorporeal membrane oxygenation (ECMO) is needed. The surviving individuals need long-term follow-up as it is not clear what their prognosis is. Aim: To provide a complex clinical picture of patients during follow-up exceeding one year after the ECMO therapy due to severe COVID-19. Methods: All subjects involved in the study required ECMO in the acute stage of COVID-19. The survivors were followed-up for over one year at a specialized respiratory medical center. Results: Of the 41 patients indicated for ECMO, 17 patients (64.7% males) survived. The average age of survivors was 47.8 years, and the average BMI was 34.7 kg center dot m(-2). The duration of ECMO support was 9.4 days. A mild decrease in vital capacity (VC) and transfer factor (DLCO) was observed on the initial follow-up visit (82.1% and 60%, respectively). VC improved by 6.2% and by an additional 7.5% after 6 months and 1 year, respectively. DLCO improved by 21.1% after 6 months and remained stable after 1 year. Post-intensive care consequences included psychological problems and neurological impairment in 29% of patients; 64.7% of the survivors got vaccinated against SARS-CoV-2 within 12 months of hospitalization and 17.6% experienced reinfection with a mild course. Conclusion: The COVID-19 pandemic has significantly increased the need for ECMO. Patients' quality of life after ECMO is temporarily significantly reduced but most patients do not experience permanent disability.

Citovat

GENZOR, Samuel; Pavol POBEHA; Martin SIMEK; Petr JAKUBEC; Jan MIZERA; Martin VYKOPAL; Milan SOVA; Jakub VANEK a Jan PRASKO. Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19. LIFE-BASEL. BASEL: MDPI, 2023, roč. 13, č. 4, s. 1-11. ISSN 2075-1729. Dostupné z: https://doi.org/10.3390/life13041054.

@article{2296999,
   author = {Genzor, Samuel and Pobeha, Pavol and Simek, Martin and Jakubec, Petr and Mizera, Jan and Vykopal, Martin and Sova, Milan and Vanek, Jakub and Prasko, Jan},
   article_location = {BASEL},
   article_number = {4},
   doi = {https://doi.org/10.3390/life13041054},
   keywords = {ECMO; COVID-19; long-term outcome},
   language = {eng},
   issn = {2075-1729},
   journal = {LIFE-BASEL},
   title = {Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19},
   url = {https://www.mdpi.com/2075-1729/13/4/1054},
   volume = {13},
   year = {2023}
}

TY  - JOUR
ID  - 2296999
AU  - Genzor, Samuel - Pobeha, Pavol - Simek, Martin - Jakubec, Petr - Mizera, Jan - Vykopal, Martin - Sova, Milan - Vanek, Jakub - Prasko, Jan
PY  - 2023
TI  - Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19
JF  - LIFE-BASEL
VL  - 13
IS  - 4
SP  - 1-11
EP  - 1-11
PB  - MDPI
SN  - 20751729
KW  - ECMO
KW  - COVID-19
KW  - long-term outcome
UR  - https://www.mdpi.com/2075-1729/13/4/1054
N2  - Introduction: Severe respiratory failure is one of the most serious complications of coronavirus disease 2019 (COVID-19). In a small proportion of patients, mechanical ventilation fails to provide adequate oxygenation and extracorporeal membrane oxygenation (ECMO) is needed. The surviving individuals need long-term follow-up as it is not clear what their prognosis is. Aim: To provide a complex clinical picture of patients during follow-up exceeding one year after the ECMO therapy due to severe COVID-19. Methods: All subjects involved in the study required ECMO in the acute stage of COVID-19. The survivors were followed-up for over one year at a specialized respiratory medical center. Results: Of the 41 patients indicated for ECMO, 17 patients (64.7% males) survived. The average age of survivors was 47.8 years, and the average BMI was 34.7 kg center dot m(-2). The duration of ECMO support was 9.4 days. A mild decrease in vital capacity (VC) and transfer factor (DLCO) was observed on the initial follow-up visit (82.1% and 60%, respectively). VC improved by 6.2% and by an additional 7.5% after 6 months and 1 year, respectively. DLCO improved by 21.1% after 6 months and remained stable after 1 year. Post-intensive care consequences included psychological problems and neurological impairment in 29% of patients; 64.7% of the survivors got vaccinated against SARS-CoV-2 within 12 months of hospitalization and 17.6% experienced reinfection with a mild course. Conclusion: The COVID-19 pandemic has significantly increased the need for ECMO. Patients' quality of life after ECMO is temporarily significantly reduced but most patients do not experience permanent disability.
ER  -

GENZOR, Samuel; Pavol POBEHA; Martin SIMEK; Petr JAKUBEC; Jan MIZERA; Martin VYKOPAL; Milan SOVA; Jakub VANEK a Jan PRASKO. Long-Term Follow-Up of Patients Needing Extracorporeal Membrane Oxygenation Following a Critical Course of COVID-19. \textit{LIFE-BASEL}. BASEL: MDPI, 2023, roč.~13, č.~4, s.~1-11. ISSN~2075-1729. Dostupné z: https://doi.org/10.3390/life13041054.

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