Is the oxidative potential of components of fine particulate
matter surface-mediated?

J 2023

Is the oxidative potential of components of fine particulate matter surface-mediated?

BAUMANN, Karsten; Marco WIETZORECK; Pourya SHAHPOURY; Alexander FILIPPI; Stefanie HILDMANN et al.

Základní údaje

Originální název

Is the oxidative potential of components of fine particulate matter surface-mediated?

Autoři

BAUMANN, Karsten; Marco WIETZORECK; Pourya SHAHPOURY; Alexander FILIPPI; Stefanie HILDMANN; Steven LELIEVELD; Thomas BERKEMEIER; Haijie TONG; Ulrich POESCHL a Gerhard LAMMEL

Vydání

Environmental Science and Pollution Research, HEIDELBERG (GERMANY), Springer, 2023, 0944-1344

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.800 v roce 2022

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/23:00132201

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Aerosol; Inhalation; Toxic quinones; Alveolar surfactant; Acellular assay

Štítky

143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 11. 2023 20:03, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

Redox-active substances in fine particulate matter (PM) contribute to inhalation health risks through their potential to generate reactive oxygen species in epithelial lung lining fluid (ELF). The ELF's air-liquid interface (ALI) can play an important role in the phase transfer and multi-phase reactions of redox-active PM constituents. We investigated the influence of interfacial processes and properties by scrubbing of coated nano-particles with simulated ELF in a nebulizing mist chamber. Weakly water-soluble redox-active organics abundant in ambient fine PM were reproducibly loaded into ELF via ALI mixing. The resulting oxidative potential (OP) of selected quinones and other PAH derivatives were found to exceed the OP resulting from bulk mixing of the same amounts of redox-active substances and ELF. Our results indicate that the OP of PM components depends not only on the PM substance properties but also on the ELF interface properties and uptake mechanisms. OP measurements based on bulk mixing of phases may not represent the effective OP in the human lung.

Citovat

BAUMANN, Karsten; Marco WIETZORECK; Pourya SHAHPOURY; Alexander FILIPPI; Stefanie HILDMANN; Steven LELIEVELD; Thomas BERKEMEIER; Haijie TONG; Ulrich POESCHL a Gerhard LAMMEL. Is the oxidative potential of components of fine particulate matter surface-mediated? Environmental Science and Pollution Research. HEIDELBERG (GERMANY): Springer, 2023, roč. 30, č. 6, s. 16749-16755. ISSN 0944-1344. Dostupné z: https://doi.org/10.1007/s11356-022-24897-3.

@article{2336938,
   author = {Baumann, Karsten and Wietzoreck, Marco and Shahpoury, Pourya and Filippi, Alexander and Hildmann, Stefanie and Lelieveld, Steven and Berkemeier, Thomas and Tong, Haijie and Poeschl, Ulrich and Lammel, Gerhard},
   article_location = {HEIDELBERG (GERMANY)},
   article_number = {6},
   doi = {https://doi.org/10.1007/s11356-022-24897-3},
   keywords = {Aerosol; Inhalation; Toxic quinones; Alveolar surfactant; Acellular assay},
   language = {eng},
   issn = {0944-1344},
   journal = {Environmental Science and Pollution Research},
   title = {Is the oxidative potential of components of fine particulate matter surface-mediated?},
   url = {https://link.springer.com/article/10.1007/s11356-022-24897-3},
   volume = {30},
   year = {2023}
}

TY  - JOUR
ID  - 2336938
AU  - Baumann, Karsten - Wietzoreck, Marco - Shahpoury, Pourya - Filippi, Alexander - Hildmann, Stefanie - Lelieveld, Steven - Berkemeier, Thomas - Tong, Haijie - Poeschl, Ulrich - Lammel, Gerhard
PY  - 2023
TI  - Is the oxidative potential of components of fine particulate matter surface-mediated?
JF  - Environmental Science and Pollution Research
VL  - 30
IS  - 6
SP  - 16749-16755
EP  - 16749-16755
PB  - Springer
SN  - 09441344
KW  - Aerosol
KW  - Inhalation
KW  - Toxic quinones
KW  - Alveolar surfactant
KW  - Acellular assay
UR  - https://link.springer.com/article/10.1007/s11356-022-24897-3
N2  - Redox-active substances in fine particulate matter (PM) contribute to inhalation health risks through their potential to generate reactive oxygen species in epithelial lung lining fluid (ELF). The ELF's air-liquid interface (ALI) can play an important role in the phase transfer and multi-phase reactions of redox-active PM constituents. We investigated the influence of interfacial processes and properties by scrubbing of coated nano-particles with simulated ELF in a nebulizing mist chamber. Weakly water-soluble redox-active organics abundant in ambient fine PM were reproducibly loaded into ELF via ALI mixing. The resulting oxidative potential (OP) of selected quinones and other PAH derivatives were found to exceed the OP resulting from bulk mixing of the same amounts of redox-active substances and ELF. Our results indicate that the OP of PM components depends not only on the PM substance properties but also on the ELF interface properties and uptake mechanisms. OP measurements based on bulk mixing of phases may not represent the effective OP in the human lung.
ER  -

BAUMANN, Karsten; Marco WIETZORECK; Pourya SHAHPOURY; Alexander FILIPPI; Stefanie HILDMANN; Steven LELIEVELD; Thomas BERKEMEIER; Haijie TONG; Ulrich POESCHL a Gerhard LAMMEL. Is the oxidative potential of components of fine particulate matter surface-mediated? \textit{Environmental Science and Pollution Research}. HEIDELBERG (GERMANY): Springer, 2023, roč.~30, č.~6, s.~16749-16755. ISSN~0944-1344. Dostupné z: https://doi.org/10.1007/s11356-022-24897-3.

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