Is the oxidative potential of components of fine particulate
matter surface-mediated?

J 2023

Is the oxidative potential of components of fine particulate matter surface-mediated?

BAUMANN, Karsten, Marco WIETZORECK, Pourya SHAHPOURY, Alexander FILIPPI, Stefanie HILDMANN et. al.

Basic information

Original name

Is the oxidative potential of components of fine particulate matter surface-mediated?

Authors

Edition

Environmental Science and Pollution Research, HEIDELBERG (GERMANY), Springer, 2023, 0944-1344

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.800 in 2022

RIV identification code

RIV/00216224:14310/23:00132201

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1007/s11356-022-24897-3

UT WoS

000903263100004

Keywords in English

Aerosol; Inhalation; Toxic quinones; Alveolar surfactant; Acellular assay

Abstract

V originále

Redox-active substances in fine particulate matter (PM) contribute to inhalation health risks through their potential to generate reactive oxygen species in epithelial lung lining fluid (ELF). The ELF's air-liquid interface (ALI) can play an important role in the phase transfer and multi-phase reactions of redox-active PM constituents. We investigated the influence of interfacial processes and properties by scrubbing of coated nano-particles with simulated ELF in a nebulizing mist chamber. Weakly water-soluble redox-active organics abundant in ambient fine PM were reproducibly loaded into ELF via ALI mixing. The resulting oxidative potential (OP) of selected quinones and other PAH derivatives were found to exceed the OP resulting from bulk mixing of the same amounts of redox-active substances and ELF. Our results indicate that the OP of PM components depends not only on the PM substance properties but also on the ELF interface properties and uptake mechanisms. OP measurements based on bulk mixing of phases may not represent the effective OP in the human lung.

Citovat

BAUMANN, Karsten, Marco WIETZORECK, Pourya SHAHPOURY, Alexander FILIPPI, Stefanie HILDMANN, Steven LELIEVELD, Thomas BERKEMEIER, Haijie TONG, Ulrich POESCHL and Gerhard LAMMEL. Is the oxidative potential of components of fine particulate matter surface-mediated? Environmental Science and Pollution Research. HEIDELBERG (GERMANY): Springer, 2023, vol. 30, No 6, p. 16749-16755. ISSN 0944-1344. Available from: https://dx.doi.org/10.1007/s11356-022-24897-3.

@article{2336938,
   author = {Baumann, Karsten and Wietzoreck, Marco and Shahpoury, Pourya and Filippi, Alexander and Hildmann, Stefanie and Lelieveld, Steven and Berkemeier, Thomas and Tong, Haijie and Poeschl, Ulrich and Lammel, Gerhard},
   article_location = {HEIDELBERG (GERMANY)},
   article_number = {6},
   doi = {http://dx.doi.org/10.1007/s11356-022-24897-3},
   keywords = {Aerosol; Inhalation; Toxic quinones; Alveolar surfactant; Acellular assay},
   language = {eng},
   issn = {0944-1344},
   journal = {Environmental Science and Pollution Research},
   title = {Is the oxidative potential of components of fine particulate matter surface-mediated?},
   url = {https://link.springer.com/article/10.1007/s11356-022-24897-3},
   volume = {30},
   year = {2023}
}

TY  - JOUR
ID  - 2336938
AU  - Baumann, Karsten - Wietzoreck, Marco - Shahpoury, Pourya - Filippi, Alexander - Hildmann, Stefanie - Lelieveld, Steven - Berkemeier, Thomas - Tong, Haijie - Poeschl, Ulrich - Lammel, Gerhard
PY  - 2023
TI  - Is the oxidative potential of components of fine particulate matter surface-mediated?
JF  - Environmental Science and Pollution Research
VL  - 30
IS  - 6
SP  - 16749-16755
EP  - 16749-16755
PB  - Springer
SN  - 09441344
KW  - Aerosol
KW  - Inhalation
KW  - Toxic quinones
KW  - Alveolar surfactant
KW  - Acellular assay
UR  - https://link.springer.com/article/10.1007/s11356-022-24897-3
N2  - Redox-active substances in fine particulate matter (PM) contribute to inhalation health risks through their potential to generate reactive oxygen species in epithelial lung lining fluid (ELF). The ELF's air-liquid interface (ALI) can play an important role in the phase transfer and multi-phase reactions of redox-active PM constituents. We investigated the influence of interfacial processes and properties by scrubbing of coated nano-particles with simulated ELF in a nebulizing mist chamber. Weakly water-soluble redox-active organics abundant in ambient fine PM were reproducibly loaded into ELF via ALI mixing. The resulting oxidative potential (OP) of selected quinones and other PAH derivatives were found to exceed the OP resulting from bulk mixing of the same amounts of redox-active substances and ELF. Our results indicate that the OP of PM components depends not only on the PM substance properties but also on the ELF interface properties and uptake mechanisms. OP measurements based on bulk mixing of phases may not represent the effective OP in the human lung.
ER  -

BAUMANN, Karsten, Marco WIETZORECK, Pourya SHAHPOURY, Alexander FILIPPI, Stefanie HILDMANN, Steven LELIEVELD, Thomas BERKEMEIER, Haijie TONG, Ulrich POESCHL and Gerhard LAMMEL. Is the oxidative potential of components of fine particulate matter surface-mediated? \textit{Environmental Science and Pollution Research}. HEIDELBERG (GERMANY): Springer, 2023, vol.~30, No~6, p.~16749-16755. ISSN~0944-1344. Available from: https://dx.doi.org/10.1007/s11356-022-24897-3.

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