The Use of Medical Grade Honey on Infected Chronic Diabetic
Foot Ulcers-A Prospective Case-Control Study

J 2023

The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study

HOLUBOVA, Adela, Lucie CHLUPACOVA, Jitka KROCOVA, Lada CETLOVA, Linsey J F PETERS et. al.

Základní údaje

Originální název

The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study

Autoři

HOLUBOVA, Adela (203 Česká republika), Lucie CHLUPACOVA (203 Česká republika), Jitka KROCOVA (203 Česká republika), Lada CETLOVA (203 Česká republika), Linsey J F PETERS (528 Nizozemské království), Niels A J CREMERS (528 Nizozemské království) a Andrea POKORNÁ (203 Česká republika, domácí)

Vydání

Antibiotics-Basel, BASEL, MDPI, 2023, 2079-6382

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30307 Nursing

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.800 v roce 2022

Kód RIV

RIV/00216224:14110/23:00132218

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.3390/antibiotics12091364

UT WoS

001071367300001

Klíčová slova anglicky

medical grade honey; diabetic foot ulcer; diabetes; anti-inflammatory treatment; glycaemia

Štítky

14110611, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 13. 11. 2023 08:58, Mgr. Tereza Miškechová

Anotace

V originále

Non-healing wounds are usually colonised and contaminated by different types of bacteria. An alternative to antibiotic treatment in patients with infected wounds with local signs of inflammation may be medical grade honey (MGH). MGH has antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory features. This study aims to evaluate the effect of MGH therapy on infected non-healing wounds, especially for diabetic foot syndrome. Prospective, observational case series (n = 5) of patients with wounds of diabetic foot syndrome are presented. There were five males with an average age of 61.6 years. All wounds were treated with MGH, and the healing trajectory was rigorously and objectively monitored. In all cases, there was a gradual disappearance of odour, pain, and exudation. Moreover, the wound areas significantly reduced within 40 days and there was a decrease in glycated haemoglobin and glycaemia values. All these outcomes resulted in improved quality of life of the patients. Despite bacterial colonisation, antibiotic treatment was not necessary. All wounds were completely healed. MGH has antimicrobial, anti-inflammatory, and antioxidant effects in diabetic foot syndrome wounds, does not increase glycated haemoglobin or glycaemia levels, and thus constitutes an effective alternative to the use of antibiotics in the treatment of locally infected wounds.

Citovat

HOLUBOVA, Adela, Lucie CHLUPACOVA, Jitka KROCOVA, Lada CETLOVA, Linsey J F PETERS, Niels A J CREMERS a Andrea POKORNÁ. The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study. Antibiotics-Basel. BASEL: MDPI, 2023, roč. 12, č. 9, s. 1-18. ISSN 2079-6382. Dostupné z: https://dx.doi.org/10.3390/antibiotics12091364.

@article{2338643,
   author = {Holubova, Adela and Chlupacova, Lucie and Krocova, Jitka and Cetlova, Lada and Peters, Linsey J F and Cremers, Niels A J and Pokorná, Andrea},
   article_location = {BASEL},
   article_number = {9},
   doi = {http://dx.doi.org/10.3390/antibiotics12091364},
   keywords = {medical grade honey; diabetic foot ulcer; diabetes; anti-inflammatory treatment; glycaemia},
   language = {eng},
   issn = {2079-6382},
   journal = {Antibiotics-Basel},
   title = {The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study},
   url = {https://www.mdpi.com/2079-6382/12/9/1364},
   volume = {12},
   year = {2023}
}

TY  - JOUR
ID  - 2338643
AU  - Holubova, Adela - Chlupacova, Lucie - Krocova, Jitka - Cetlova, Lada - Peters, Linsey J F - Cremers, Niels A J - Pokorná, Andrea
PY  - 2023
TI  - The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study
JF  - Antibiotics-Basel
VL  - 12
IS  - 9
SP  - 1-18
EP  - 1-18
PB  - MDPI
SN  - 20796382
KW  - medical grade honey
KW  - diabetic foot ulcer
KW  - diabetes
KW  - anti-inflammatory treatment
KW  - glycaemia
UR  - https://www.mdpi.com/2079-6382/12/9/1364
N2  - Non-healing wounds are usually colonised and contaminated by different types of bacteria. An alternative to antibiotic treatment in patients with infected wounds with local signs of inflammation may be medical grade honey (MGH). MGH has antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory features. This study aims to evaluate the effect of MGH therapy on infected non-healing wounds, especially for diabetic foot syndrome. Prospective, observational case series (n = 5) of patients with wounds of diabetic foot syndrome are presented. There were five males with an average age of 61.6 years. All wounds were treated with MGH, and the healing trajectory was rigorously and objectively monitored. In all cases, there was a gradual disappearance of odour, pain, and exudation. Moreover, the wound areas significantly reduced within 40 days and there was a decrease in glycated haemoglobin and glycaemia values. All these outcomes resulted in improved quality of life of the patients. Despite bacterial colonisation, antibiotic treatment was not necessary. All wounds were completely healed. MGH has antimicrobial, anti-inflammatory, and antioxidant effects in diabetic foot syndrome wounds, does not increase glycated haemoglobin or glycaemia levels, and thus constitutes an effective alternative to the use of antibiotics in the treatment of locally infected wounds.
ER  -

HOLUBOVA, Adela, Lucie CHLUPACOVA, Jitka KROCOVA, Lada CETLOVA, Linsey J F PETERS, Niels A J CREMERS a Andrea POKORNÁ. The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study. \textit{Antibiotics-Basel}. BASEL: MDPI, 2023, roč.~12, č.~9, s.~1-18. ISSN~2079-6382. Dostupné z: https://dx.doi.org/10.3390/antibiotics12091364.

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