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@article{2365504,
author = {Kursvietiene, Lolita and Kopustinskiene, Dalia M and Staneviciene, Inga and Mongirdiene, Ausra and Kubová, Kateřina and Masteiková, Ruta and Bernatoniene, Jurga},
article_location = {Basel},
article_number = {12},
doi = {http://dx.doi.org/10.3390/antiox12122056},
keywords = {resveratrol; cancer; mitochondria},
language = {eng},
issn = {2076-3921},
journal = {Antioxidants},
title = {Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions},
url = {https://www.mdpi.com/2076-3921/12/12/2056},
volume = {12},
year = {2023}
}
TY - JOUR
ID - 2365504
AU - Kursvietiene, Lolita - Kopustinskiene, Dalia M - Staneviciene, Inga - Mongirdiene, Ausra - Kubová, Kateřina - Masteiková, Ruta - Bernatoniene, Jurga
PY - 2023
TI - Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions
JF - Antioxidants
VL - 12
IS - 12
SP - 1-24
EP - 1-24
PB - MDPI
SN - 20763921
KW - resveratrol
KW - cancer
KW - mitochondria
UR - https://www.mdpi.com/2076-3921/12/12/2056
N2 - Cancer is one of the most serious public health issues worldwide, demanding ongoing efforts to find novel therapeutic agents and approaches. Amid growing interest in the oncological applications of phytochemicals, particularly polyphenols, resveratrol-a naturally occurring polyphenolic stilbene derivative-has emerged as a candidate of interest. This review analyzes the pleiotropic anti-cancer effects of resveratrol, including its modulation of apoptotic pathways, cell cycle regulation, inflammation, angiogenesis, and metastasis, its interaction with cancer stem cells and the tumor microenvironment. The effects of resveratrol on mitochondrial functions, which are crucial to cancer development, are also discussed. Future research directions are identified, including the elucidation of specific molecular targets, to facilitate the clinical translation of resveratrol in cancer prevention and therapy.
ER -
KURSVIETIENE, Lolita, Dalia M KOPUSTINSKIENE, Inga STANEVICIENE, Ausra MONGIRDIENE, Kateřina KUBOVÁ, Ruta MASTEIKOVÁ a Jurga BERNATONIENE. Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions. \textit{Antioxidants}. Basel: MDPI, 2023, roč.~12, č.~12, s.~1-24. ISSN~2076-3921. Dostupné z: https://dx.doi.org/10.3390/antiox12122056.
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