Bilateral and multiple non-syndromic dentigerous cysts – are
they that rare?

a 2023

Bilateral and multiple non-syndromic dentigerous cysts – are they that rare?

SZÁRAZ, Dávid, Zdeněk DANĚK, Ctirad MACHÁČEK a Petra BOŘILOVÁ LINHARTOVÁ

Základní údaje

Originální název

Bilateral and multiple non-syndromic dentigerous cysts – are they that rare?

Autoři

SZÁRAZ, Dávid (203 Česká republika), Zdeněk DANĚK (203 Česká republika), Ctirad MACHÁČEK (203 Česká republika) a Petra BOŘILOVÁ LINHARTOVÁ (203 Česká republika, garant, domácí)

Vydání

ICOMS, 2023, 2023

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30101 Human genetics

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/23:00133528

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ijom.2023.10.458

Klíčová slova anglicky

dentigerous cysts; odontogenic cysts; dysplasia

Změněno: 17. 4. 2024 09:37, Mgr. Terezie Slámová

Anotace

V originále

Background: Dentigerous cysts (DCs) are the most common developmental odontogenic cysts (OCs) and the second most common cysts of the jaws. Bilateral and multiple DCs are usually associated with various syndromes, such as mucopolysaccharidoses or cleidocranial dysplasia; however, they are generally considered to be rare (1.8 – 3 %) in non-syndromic patients. Objectives: Here, we aimed to investigate the incidence of bilateral and multiple DCs in our cohort of patients with OCs. Methods: Patients with suspected OCs examined in 2022 at the University Hospital Brno and meeting all of the following criteria were included in the study: i) well-circumscribed translucency of the cyst associated with an impacted tooth on the OPG, ii) histopathological confirmation of OC. Patients with recurrent cysts were excluded from the study. Findings: In total, 48 patients with newly diagnosed developmental OCs were identified. 7 patients had an odontogenic keratocyst (mean age 37.8 years, 66.6% of men) and 41 patients met the criteria for DCs (mean age 43.9 years, 65.9 % of men); none of the DC patients suffered from a syndrome. Bilateral DCs adjacent to the lower wisdom teeth were presented in 2 patients, another patient had multiple DCs located around upper right wisdom tooth and the lower third molars. Our findings showed that 7.3 % of patients with a DC presented multiple DCs. Conclusion: While multiple DCs are rarer than sporadic single DCs, we suggest avoiding phrases such as “extremely rare” for describing the occurrence of multiple non-syndromic DCs. Compared to some other rare multiple developmental OCs such as the orthokeratinizing odontogenic cyst, multiple non-syndromic DCs are much more common.

Návaznosti

LM2018121, projekt VaV

Název: Výzkumná infrastruktura RECETOX (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX RI

NU20-08-00205, projekt VaV

Název: Molekulární etiopatogeneze apikální periodontitidy a odontogenních cyst

Investor: Ministerstvo zdravotnictví ČR, Molekulární etiopatogeneze apikální periodontitidy a odontogenních cyst, Podprogram 1 - standardní

Citovat

SZÁRAZ, Dávid, Zdeněk DANĚK, Ctirad MACHÁČEK a Petra BOŘILOVÁ LINHARTOVÁ. Bilateral and multiple non-syndromic dentigerous cysts – are they that rare? In ICOMS, 2023. 2023. Dostupné z: https://dx.doi.org/10.1016/j.ijom.2023.10.458.

@proceedings{2373846,
   author = {Száraz, Dávid and Daněk, Zdeněk and Macháček, Ctirad and Bořilová Linhartová, Petra},
   booktitle = {ICOMS, 2023},
   doi = {http://dx.doi.org/10.1016/j.ijom.2023.10.458},
   keywords = {dentigerous cysts; odontogenic cysts; dysplasia},
   language = {eng},
   title = {Bilateral and multiple non-syndromic dentigerous cysts – are they that rare?},
   year = {2023}
}

TY  - CONF
ID  - 2373846
AU  - Száraz, Dávid - Daněk, Zdeněk - Macháček, Ctirad - Bořilová Linhartová, Petra
PY  - 2023
TI  - Bilateral and multiple non-syndromic dentigerous cysts – are they that rare?
KW  - dentigerous cysts
KW  - odontogenic cysts
KW  - dysplasia
N2  - Background: Dentigerous cysts (DCs) are the most common developmental odontogenic cysts (OCs) and the second most common cysts of the jaws. Bilateral and multiple DCs are usually associated with various syndromes, such as mucopolysaccharidoses or cleidocranial dysplasia; however, they are generally considered to be rare (1.8 – 3 %) in non-syndromic patients. Objectives: Here, we aimed to investigate the incidence of bilateral and multiple DCs in our cohort of patients with OCs. Methods: Patients with suspected OCs examined in 2022 at the University Hospital Brno and meeting all of the following criteria were included in the study: i) well-circumscribed translucency of the cyst associated with an impacted tooth on the OPG, ii) histopathological confirmation of OC. Patients with recurrent cysts were excluded from the study. Findings: In total, 48 patients with newly diagnosed developmental OCs were identified. 7 patients had an odontogenic keratocyst (mean age 37.8 years, 66.6% of men) and 41 patients met the criteria for DCs (mean age 43.9 years, 65.9 % of men); none of the DC patients suffered from a syndrome. Bilateral DCs adjacent to the lower wisdom teeth were presented in 2 patients, another patient had multiple DCs located around upper right wisdom tooth and the lower third molars. Our findings showed that 7.3 % of patients with a DC presented multiple DCs. Conclusion: While multiple DCs are rarer than sporadic single DCs, we suggest avoiding phrases such as “extremely rare” for describing the occurrence of multiple non-syndromic DCs. Compared to some other rare multiple developmental OCs such as the orthokeratinizing odontogenic cyst, multiple non-syndromic DCs are much more common.
ER  -

SZÁRAZ, Dávid, Zdeněk DANĚK, Ctirad MACHÁČEK a Petra BOŘILOVÁ LINHARTOVÁ. Bilateral and multiple non-syndromic dentigerous cysts – are they that rare? In \textit{ICOMS, 2023}. 2023. Dostupné z: https://dx.doi.org/10.1016/j.ijom.2023.10.458.

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