Decreased quality of life in Duchenne muscular disease patients
related to functional neurological and cardiac impairment

J 2024

Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment

JUŘÍKOVÁ, Lenka; Lucia MASÁROVÁ; Roman PANOVSKÝ; Martin PEŠL; Kamila ŽONDRA REVENDOVÁ et al.

Základní údaje

Originální název

Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment

Autoři

Vydání

Frontiers in Neurology, LAUSANNE, FRONTIERS MEDIA SA, 2024, 1664-2295

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.800

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/24:00135520

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

quality of life; Duchenne muscular dystrophy; cardiac magnetic resonance; neurological status; cardiac impairment

Štítky

14110115, 14110132, 14110221, 14110320, 14110513

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 2. 2025 14:16, Mgr. Tereza Miškechová

Anotace

V originále

In this prospective study involving 37 Duchenne muscular dystrophy (DMD) patients aged 8–18 years and older, we examined the impact of neurological and cardiac factors on quality of life (QoL). Our findings revealed a negative correlation between upper limb movement and overall mobility, self-service, and usual activities. Ambulatory and non-ambulatory DMD patients showed significant differences in mobility-related parameters. Cardiac evaluations demonstrated associations between mitral annular plane systolic excursion (MAPSE) and mobility-related aspects. The PEDSQL 3.0 neuromuscular model questionnaire further highlighted age-related and movement-related correlations with QoL. The loss of ambulatory status and reduced upper limb movement were negatively associated with QoL, while upper limb movement positively correlated with septal MAPSE. However, no significant associations were found between MAPSE and anxiety/depression. These findings underscore the multifaceted impact of DMD on QoL and emphasize the importance of considering both neurological and cardiac factors in comprehensive patient care.

Návaznosti

MUNI/A/1525/2023, interní kód MU

Název: Diagnostika komplikací a komorbidit neurologických onemocnění

Investor: Masarykova univerzita, Diagnostika komplikací a komorbidit neurologických onemocnění

MUNI/A/1624/2023, interní kód MU

Název: Srdeční selhání, jeho komorbidity a etiologické příčiny

Investor: Masarykova univerzita, Srdeční selhání, jeho komorbidity a etiologické příčiny

Citovat

JUŘÍKOVÁ, Lenka; Lucia MASÁROVÁ; Roman PANOVSKÝ; Martin PEŠL; Kamila ŽONDRA REVENDOVÁ; Ondřej VOLNÝ; Věra FEITOVÁ; Tomáš HOLEČEK; Vladimír KINCL; Pavlína DANHOFER; Stanislav VOHÁŇKA; Jana HABERLOVÁ a Podolská KAROLÍNA. Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment. Frontiers in Neurology. LAUSANNE: FRONTIERS MEDIA SA, 2024, roč. 15, February 2024, s. 1-11. ISSN 1664-2295. Dostupné z: https://doi.org/10.3389/fneur.2024.1360385.

@article{2374257,
   author = {Juříková, Lenka and Masárová, Lucia and Panovský, Roman and Pešl, Martin and Žondra Revendová, Kamila and Volný, Ondřej and Feitová, Věra and Holeček, Tomáš and Kincl, Vladimír and Danhofer, Pavlína and Voháňka, Stanislav and Haberlová, Jana and Karolína, Podolská},
   article_location = {LAUSANNE},
   article_number = {February 2024},
   doi = {https://doi.org/10.3389/fneur.2024.1360385},
   keywords = {quality of life; Duchenne muscular dystrophy; cardiac magnetic resonance; neurological status; cardiac impairment},
   language = {eng},
   issn = {1664-2295},
   journal = {Frontiers in Neurology},
   title = {Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment},
   url = {https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1360385/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE},
   volume = {15},
   year = {2024}
}

TY  - JOUR
ID  - 2374257
AU  - Juříková, Lenka - Masárová, Lucia - Panovský, Roman - Pešl, Martin - Žondra Revendová, Kamila - Volný, Ondřej - Feitová, Věra - Holeček, Tomáš - Kincl, Vladimír - Danhofer, Pavlína - Voháňka, Stanislav - Haberlová, Jana - Karolína, Podolská
PY  - 2024
TI  - Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment
JF  - Frontiers in Neurology
VL  - 15
IS  - February 2024
SP  - 1-11
EP  - 1-11
PB  - FRONTIERS MEDIA SA
SN  - 16642295
KW  - quality of life
KW  - Duchenne muscular dystrophy
KW  - cardiac magnetic resonance
KW  - neurological status
KW  - cardiac impairment
UR  - https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1360385/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE
N2  - In this prospective study involving 37 Duchenne muscular dystrophy (DMD) patients aged 8–18 years and older, we examined the impact of neurological and cardiac factors on quality of life (QoL). Our findings revealed a negative correlation between upper limb movement and overall mobility, self-service, and usual activities. Ambulatory and non-ambulatory DMD patients showed significant differences in mobility-related parameters. Cardiac evaluations demonstrated associations between mitral annular plane systolic excursion (MAPSE) and mobility-related aspects. The PEDSQL 3.0 neuromuscular model questionnaire further highlighted age-related and movement-related correlations with QoL. The loss of ambulatory status and reduced upper limb movement were negatively associated with QoL, while upper limb movement positively correlated with septal MAPSE. However, no significant associations were found between MAPSE and anxiety/depression. These findings underscore the multifaceted impact of DMD on QoL and emphasize the importance of considering both neurological and cardiac factors in comprehensive patient care.
ER  -

JUŘÍKOVÁ, Lenka; Lucia MASÁROVÁ; Roman PANOVSKÝ; Martin PEŠL; Kamila ŽONDRA REVENDOVÁ; Ondřej VOLNÝ; Věra FEITOVÁ; Tomáš HOLEČEK; Vladimír KINCL; Pavlína DANHOFER; Stanislav VOHÁŇKA; Jana HABERLOVÁ a Podolská KAROLÍNA. Decreased quality of life in Duchenne muscular disease patients related to functional neurological and cardiac impairment. \textit{Frontiers in Neurology}. LAUSANNE: FRONTIERS MEDIA SA, 2024, roč.~15, February 2024, s.~1-11. ISSN~1664-2295. Dostupné z: https://doi.org/10.3389/fneur.2024.1360385.

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