Light-activatable H2S donors

C 2022

Light-activatable H2S donors

KLÁN, Petr, Tomáš SLANINA a Peter ŠTACKO

Základní údaje

Originální název

Light-activatable H2S donors

Autoři

KLÁN, Petr (203 Česká republika, domácí), Tomáš SLANINA a Peter ŠTACKO

Vydání

Hoboken, Hydrogen Sulfide : Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies, od s. 347-372, 26 s. 1st, 2022

Nakladatel

Wiley

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10401 Organic chemistry

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Kód RIV

RIV/00216224:14310/22:00133618

Organizační jednotka

Přírodovědecká fakulta

ISBN

978-1-119-79987-0

DOI

http://dx.doi.org/10.1002/9781119799900.ch14

Klíčová slova anglicky

Caged release; Delivery mechanisms; H2S donors; Photochemistry; Photorelease

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 2. 2024 14:44, Mgr. Marie Šípková, DiS.

Anotace

V originále

The chapter focuses on the release and delivery of hydrogen sulfide (H 2 S) from photoactivatable molecules using light as a biorthogonal trigger. We start with the introduction of photophysical and photochemical concepts related to their design. Standard methods of light delivery to human tissue and factors that limit the applicability of near-infrared irradiation wavelengths, allowing for deep tissue penetration, are subsequently reviewed. The most common methods of delivering light into the living organisms are briefly summarized and compared in the light of their clinical application. We show different mechanistic approaches to light-activated H 2 S release and provide a comprehensive survey of small organic molecules, organometallic complexes, supramolecular materials, and nanocomposites that can be used as H 2 S photodonors. The chapter concludes by highlighting the major challenges and obstacles to fuel future endeavors in the field of light-activated H 2 S donors.

Citovat

KLÁN, Petr, Tomáš SLANINA a Peter ŠTACKO. Light-activatable H2S donors. In Michael D. Pluth. Hydrogen Sulfide : Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies. Hoboken: Wiley, 2022, s. 347-372. 1st. ISBN 978-1-119-79987-0. Dostupné z: https://dx.doi.org/10.1002/9781119799900.ch14.

@inbook{2377199,
   author = {Klán, Petr and Slanina, Tomáš and Štacko, Peter},
   address = {Hoboken},
   booktitle = {Hydrogen Sulfide : Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies},
   doi = {http://dx.doi.org/10.1002/9781119799900.ch14},
   editor = {Michael D. Pluth},
   keywords = {Caged release; Delivery mechanisms; H2S donors; Photochemistry; Photorelease},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Hoboken},
   isbn = {978-1-119-79987-0},
   pages = {347-372},
   publisher = {Wiley},
   title = {Light-activatable H2S donors},
   url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119799900.ch14},
   year = {2022}
}

TY  - CHAP
ID  - 2377199
AU  - Klán, Petr - Slanina, Tomáš - Štacko, Peter
PY  - 2022
TI  - Light-activatable H2S donors
VL  - 1st
PB  - Wiley
CY  - Hoboken
SN  - 9781119799870
KW  - Caged release
KW  - Delivery mechanisms
KW  - H2S donors
KW  - Photochemistry
KW  - Photorelease
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119799900.ch14
N2  - The chapter focuses on the release and delivery of hydrogen sulfide (H 2 S) from photoactivatable molecules using light as a biorthogonal trigger. We start with the introduction of photophysical and photochemical concepts related to their design. Standard methods of light delivery to human tissue and factors that limit the applicability of near-infrared irradiation wavelengths, allowing for deep tissue penetration, are subsequently reviewed. The most common methods of delivering light into the living organisms are briefly summarized and compared in the light of their clinical application. We show different mechanistic approaches to light-activated H 2 S release and provide a comprehensive survey of small organic molecules, organometallic complexes, supramolecular materials, and nanocomposites that can be used as H 2 S photodonors. The chapter concludes by highlighting the major challenges and obstacles to fuel future endeavors in the field of light-activated H 2 S donors.
ER  -

KLÁN, Petr, Tomáš SLANINA a Peter ŠTACKO. Light-activatable H2S donors. In Michael D. Pluth. \textit{Hydrogen Sulfide : Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies}. Hoboken: Wiley, 2022, s.~347-372. 1st. ISBN~978-1-119-79987-0. Dostupné z: https://dx.doi.org/10.1002/9781119799900.ch14.

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