HUDEČEK, Robert, J. KLAT, K. POHL, A. PROKOPENKO, L. MIKULASEK, Soňa ŠIMOVÁ, P. KRCAL, A. SEVCIK a P. TOMES. Relugolix kombinovaná terapie a symptomy děložní myomatózy - vybrané kazuistiky indikačního spektra a výsledků léčby. CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY. PRAGUE: NAKLADATELSKE STREDISKO C L S J E PURKYNE, 2023, roč. 88, č. 5, s. 359-370. ISSN 1210-7832. Dostupné z: https://dx.doi.org/10.48095/cccg2023359. |
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@article{2386506, author = {Hudeček, Robert and Klat, J. and Pohl, K. and Prokopenko, A. and Mikulasek, L. and Šimová, Soňa and Krcal, P. and Sevcik, A. and Tomes, P.}, article_location = {PRAGUE}, article_number = {5}, doi = {http://dx.doi.org/10.48095/cccg2023359}, keywords = {relugolix combination therapy; uterine fibroid symptoms}, language = {cze}, issn = {1210-7832}, journal = {CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY}, title = {Relugolix kombinovaná terapie a symptomy děložní myomatózy - vybrané kazuistiky indikačního spektra a výsledků léčby}, url = {https://www.prolekare.cz/casopisy/ceska-gynekologie/2023-5-6/relugolix-kombinovana-terapie-a-symptomy-delozni-myomatozy-vybrane-kazuistiky-indikacniho-spektra-a-vysledku-lecby-135551}, volume = {88}, year = {2023} }
TY - JOUR ID - 2386506 AU - Hudeček, Robert - Klat, J. - Pohl, K. - Prokopenko, A. - Mikulasek, L. - Šimová, Soňa - Krcal, P. - Sevcik, A. - Tomes, P. PY - 2023 TI - Relugolix kombinovaná terapie a symptomy děložní myomatózy - vybrané kazuistiky indikačního spektra a výsledků léčby JF - CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY VL - 88 IS - 5 SP - 359-370 EP - 359-370 PB - NAKLADATELSKE STREDISKO C L S J E PURKYNE SN - 12107832 KW - relugolix combination therapy KW - uterine fibroid symptoms UR - https://www.prolekare.cz/casopisy/ceska-gynekologie/2023-5-6/relugolix-kombinovana-terapie-a-symptomy-delozni-myomatozy-vybrane-kazuistiky-indikacniho-spektra-a-vysledku-lecby-135551 N2 - Objective: An illustrative review of the indications for relugolix combination therapy (RCT) in the management of symptoms associated with uterine myomatosis. Methods: A set of annotated case reports from outpatient and clinical practice. Results: The file includes a non-invasive methodology for defining excessive menstrual bleeding using the pictorial bleeding assessment chart (PBAC). It also presents the use of RCT as a fertility-sparing procedure prior to elective myomectomy and the management of isthmic fi broids as an uterine factor of infertility. Cases of RCT of adenomyosis in primary sterility and in extragenital forms of endometriosis are commented. Emergent events associated with complications of myomatosis in pregnancy are represented by a case report of necrotizing diffuse myomatosis in puerperium. The differential-diagnostic confusion of adnexal pathology and myomatosis, RCT as a final solution to failed pharmacotherapy, and the alternative of hysterectomy in premenopause illustrate the diverse spectrum of indications for pharmacological treatment, including the possibility of dual therapy with RCT and aGnRH. Conclusion: Relugolix combination therapy as an effective and safe causal treatment expands the therapeutic spectrum and options for reproductive medicine specialists and registering gynaecologists. The availability of conservative treatment in combination with surgical treatment leads to optimalization and greater effectiveness of therapeutic procedures and increased quality of life for women with myomatosis. ER -
HUDEČEK, Robert, J. KLAT, K. POHL, A. PROKOPENKO, L. MIKULASEK, Soňa ŠIMOVÁ, P. KRCAL, A. SEVCIK a P. TOMES. Relugolix kombinovaná terapie a symptomy děložní myomatózy - vybrané kazuistiky indikačního spektra a výsledků léčby. \textit{CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY}. PRAGUE: NAKLADATELSKE STREDISKO C L S J E PURKYNE, 2023, roč.~88, č.~5, s.~359-370. ISSN~1210-7832. Dostupné z: https://dx.doi.org/10.48095/cccg2023359.
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