To Waste or Not to Waste: Questioning Potential Health Risks of
Micro- and Nanoplastics with a Focus on Their Ingestion and
Potential Carcinogenicity

J 2023

To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity

GRUBER, Elisabeth S; Vanessa STADLBAUER; Verena PICHLER; Katharina RESCH-FAUSTER; Andrea TODOROVIC et al.

Základní údaje

Originální název

To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity

Autoři

Vydání

EXPOSURE AND HEALTH, NETHERLANDS, SPRINGER, 2023, 2451-9766

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30304 Public and environmental health

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.600

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14740/23:00133952

Organizační jednotka

Středoevropský technologický institut

Klíčová slova anglicky

Microplastic; Nanoplastic; Carcinogenesis; Human health; Bioethics issue

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 10. 2024 12:32, Mgr. Eva Dubská

Anotace

V originále

Micro- and nanoplastics (MNPs) are recognized as emerging contaminants, especially in food, with unknown health significance. MNPs passing through the gastrointestinal tract have been brought in context with disruption of the gut microbiome. Several molecular mechanisms have been described to facilitate tissue uptake of MNPs, which then are involved in local inflammatory and immune responses. Furthermore, MNPs can act as potential transporters ("vectors") of contaminants and as chemosensitizers for toxic substances ("Trojan Horse effect"). In this review, we summarize current multidisciplinary knowledge of ingested MNPs and their potential adverse health effects. We discuss new insights into analytical and molecular modeling tools to help us better understand the local deposition and uptake of MNPs that might drive carcinogenic signaling. We present bioethical insights to basically re-consider the "culture of consumerism." Finally, we map out prominent research questions in accordance with the Sustainable Development Goals of the United Nations.

Citovat

GRUBER, Elisabeth S; Vanessa STADLBAUER; Verena PICHLER; Katharina RESCH-FAUSTER; Andrea TODOROVIC; Thomas C MEISEL; Sibylle TRAWOEGER; Oldamur HOLLOCZKI; Suzanne Dawn TURNER; Wolfgang WADSAK; A Dick VETHAAK a Lukas KENNER. To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity. EXPOSURE AND HEALTH. NETHERLANDS: SPRINGER, 2023, roč. 15, č. 1, s. 33-51. ISSN 2451-9766. Dostupné z: https://doi.org/10.1007/s12403-022-00470-8.

@article{2392921,
   author = {Gruber, Elisabeth S and Stadlbauer, Vanessa and Pichler, Verena and ReschandFauster, Katharina and Todorovic, Andrea and Meisel, Thomas C and Trawoeger, Sibylle and Holloczki, Oldamur and Turner, Suzanne Dawn and Wadsak, Wolfgang and Vethaak, A Dick and Kenner, Lukas},
   article_location = {NETHERLANDS},
   article_number = {1},
   doi = {https://doi.org/10.1007/s12403-022-00470-8},
   keywords = {Microplastic; Nanoplastic; Carcinogenesis; Human health; Bioethics issue},
   language = {eng},
   issn = {2451-9766},
   journal = {EXPOSURE AND HEALTH},
   title = {To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity},
   url = {https://link.springer.com/article/10.1007/s12403-022-00470-8},
   volume = {15},
   year = {2023}
}

TY  - JOUR
ID  - 2392921
AU  - Gruber, Elisabeth S - Stadlbauer, Vanessa - Pichler, Verena - Resch-Fauster, Katharina - Todorovic, Andrea - Meisel, Thomas C - Trawoeger, Sibylle - Holloczki, Oldamur - Turner, Suzanne Dawn - Wadsak, Wolfgang - Vethaak, A Dick - Kenner, Lukas
PY  - 2023
TI  - To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity
JF  - EXPOSURE AND HEALTH
VL  - 15
IS  - 1
SP  - 33-51
EP  - 33-51
PB  - SPRINGER
SN  - 24519766
KW  - Microplastic
KW  - Nanoplastic
KW  - Carcinogenesis
KW  - Human health
KW  - Bioethics issue
UR  - https://link.springer.com/article/10.1007/s12403-022-00470-8
N2  - Micro- and nanoplastics (MNPs) are recognized as emerging contaminants, especially in food, with unknown health significance. MNPs passing through the gastrointestinal tract have been brought in context with disruption of the gut microbiome. Several molecular mechanisms have been described to facilitate tissue uptake of MNPs, which then are involved in local inflammatory and immune responses. Furthermore, MNPs can act as potential transporters ("vectors") of contaminants and as chemosensitizers for toxic substances ("Trojan Horse effect"). In this review, we summarize current multidisciplinary knowledge of ingested MNPs and their potential adverse health effects. We discuss new insights into analytical and molecular modeling tools to help us better understand the local deposition and uptake of MNPs that might drive carcinogenic signaling. We present bioethical insights to basically re-consider the "culture of consumerism." Finally, we map out prominent research questions in accordance with the Sustainable Development Goals of the United Nations.
ER  -

GRUBER, Elisabeth S; Vanessa STADLBAUER; Verena PICHLER; Katharina RESCH-FAUSTER; Andrea TODOROVIC; Thomas C MEISEL; Sibylle TRAWOEGER; Oldamur HOLLOCZKI; Suzanne Dawn TURNER; Wolfgang WADSAK; A Dick VETHAAK a Lukas KENNER. To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity. \textit{EXPOSURE AND HEALTH}. NETHERLANDS: SPRINGER, 2023, roč.~15, č.~1, s.~33-51. ISSN~2451-9766. Dostupné z: https://doi.org/10.1007/s12403-022-00470-8.

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