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@article{2409480,
author = {Klail, Tomáš and Piechowiak, Eike I and Krug, Nadja and Maegerlein, Christian and Maus, Volker and Fischer, Sebastian and Lobsien, Donald and Pielenz, Daniel and Styczen, Hanna and Deuschl, Cornelius and Thormann, Maximilian and Diamandis, Elie and Heldner, Mirjam R and Kaesmacher, Johannes and Mordasini, Pasquale},
article_location = {THOUSAND OAKS},
doi = {http://dx.doi.org/10.1177/15910199241240045},
keywords = {Tandem occlusions; stroke; vertebrobasilar; mechanical thrombectomy},
language = {eng},
issn = {1591-0199},
journal = {INTERVENTIONAL NEURORADIOLOGY},
title = {Endovascular revascularization of vertebrobasilar tandem occlusions in comparison to isolated basilar artery occlusions: A multi-center experience},
url = {https://journals.sagepub.com/doi/10.1177/15910199241240045},
year = {2024}
}
TY - JOUR
ID - 2409480
AU - Klail, Tomáš - Piechowiak, Eike I - Krug, Nadja - Maegerlein, Christian - Maus, Volker - Fischer, Sebastian - Lobsien, Donald - Pielenz, Daniel - Styczen, Hanna - Deuschl, Cornelius - Thormann, Maximilian - Diamandis, Elie - Heldner, Mirjam R - Kaesmacher, Johannes - Mordasini, Pasquale
PY - 2024
TI - Endovascular revascularization of vertebrobasilar tandem occlusions in comparison to isolated basilar artery occlusions: A multi-center experience
JF - INTERVENTIONAL NEURORADIOLOGY
PB - SAGE PUBLICATIONS INC
SN - 15910199
KW - Tandem occlusions
KW - stroke
KW - vertebrobasilar
KW - mechanical thrombectomy
UR - https://journals.sagepub.com/doi/10.1177/15910199241240045
N2 - Background Acute basilar artery occlusion (BAO) is a severe disease that is associated with an 85% mortality rate if untreated. Several studies have analyzed the use of mechanical thrombectomy (MT) in the different scenarios of BAO. However, the results remain conflicting and the role of MT as standard of care for vertebrobasilar tandem occlusions (VBTO) has not been confirmed. Our goal was to assess technical feasibility, safety, and functional outcome of endovascular treatment of VBTO in comparison to isolated BAO (IBAO).Methods We retrospectively reviewed all prospectively collected patients with acute BAO from six tertiary centers between September 2016 and November 2021. Patients were subsequently divided into two groups: VBTO and IBAO. Baseline data, procedural details, and outcomes were compared between groups.Results A total of 190 patients were included, 55 presenting with a VBTO and 135 with IBAO. Successful recanalization was equally common in both groups (89.1% and 86.0%). Rates of favorable functional outcome (modified Rankin Scale: 0-2) were higher in patients with VBTO compared to IBAO (36.4% vs. 25.2%, p = 0.048) and mortality was lower (29.1% vs. 33.3%). However, these associations faded after adjustment for confounders (adjusted odds ratio [aOR] 0.86, 95% CI 0.35-2.05; aOR 0.93, 95% CI 0.35-2.45). Rates of symptomatic intracranial hemorrhage did not differ between the groups (VBTO: 7.3% vs. IBAO: 4.2%; p = 0.496).Conclusion Endovascular treatment of VBTO is technically feasible and safe with similar rates of successful recanalization, favorable functional outcome, and mortality to those in patients with IBAO.
ER -
KLAIL, Tomáš, Eike I PIECHOWIAK, Nadja KRUG, Christian MAEGERLEIN, Volker MAUS, Sebastian FISCHER, Donald LOBSIEN, Daniel PIELENZ, Hanna STYCZEN, Cornelius DEUSCHL, Maximilian THORMANN, Elie DIAMANDIS, Mirjam R HELDNER, Johannes KAESMACHER a Pasquale MORDASINI. Endovascular revascularization of vertebrobasilar tandem occlusions in comparison to isolated basilar artery occlusions: A multi-center experience. \textit{INTERVENTIONAL NEURORADIOLOGY}. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2024, 8 s. ISSN~1591-0199. Dostupné z: https://dx.doi.org/10.1177/15910199241240045.
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