Training and education on inclusivity in clinical trials-the
SENSITISE project

J 2024

Training and education on inclusivity in clinical trials-the SENSITISE project

SHIELY, Frances; Jitka RYCHLÍČKOVÁ; Christine KUBIAK; Zora ČECHOVÁ; Martina ESDAILE et al.

Základní údaje

Originální název

Training and education on inclusivity in clinical trials-the SENSITISE project

Autoři

SHIELY, Frances; Jitka RYCHLÍČKOVÁ; Christine KUBIAK; Zora ČECHOVÁ; Martina ESDAILE a Shaun TREWEEK

Vydání

Trials, LONDON, Elsevier, 2024, 1745-6215

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30230 Other clinical medicine subjects

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.000

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/24:00136478

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

clinical trials; training; education

Štítky

14110516, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 1. 2025 13:18, Mgr. Tereza Miškechová

Anotace

V originále

There have been calls globally to improve participation in clinical trials of groups that traditionally have been under-represented. These under-served groups are populations under-represented or disengaged from medical research or services despite having a disproportionately high healthcare burden. INCLUDE, a 2017 initiative from the UK’s National Institute of Health Research (NIHR), has defined and identified under-served groups in clinical trials (elderly, ethnic minorities, the socioeconomically disadvantaged, pregnant and lactating women, the LGBTQ+ community, rural dwellers, those with comorbidities including disability, mental health conditions or cognitive impairment, amongst others) and barriers for recruitment. Trial conclusions cannot with certainty support treatment decisions (or mode of treatment delivery) for those not represented in the trial. This perpetuates inequality, is immoral and represents bad science. It can also lead to general distrust in research amongst under-served groups. Designing and conducting clinical trials is a complex task, and all involved agree that investigators need adequate training to perform their duties. Despite this, there is no formal training on inclusivity in clinical trials available globally.

Návaznosti

LM2023049, projekt VaV

Název: Český národní uzel Evropské sítě infrastruktur klinického výzkumu

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CZECRIN - Czech National Node to the European Clinical Research Infrastructure Network

Citovat

SHIELY, Frances; Jitka RYCHLÍČKOVÁ; Christine KUBIAK; Zora ČECHOVÁ; Martina ESDAILE a Shaun TREWEEK. Training and education on inclusivity in clinical trials-the SENSITISE project. Trials. LONDON: Elsevier, 2024, roč. 25, č. 1, s. 1-2. ISSN 1745-6215. Dostupné z: https://doi.org/10.1186/s13063-024-08150-5.

@article{2417979,
   author = {Shiely, Frances and Rychlíčková, Jitka and Kubiak, Christine and Čechová, Zora and Esdaile, Martina and Treweek, Shaun},
   article_location = {LONDON},
   article_number = {1},
   doi = {https://doi.org/10.1186/s13063-024-08150-5},
   keywords = {clinical trials; training; education},
   language = {eng},
   issn = {1745-6215},
   journal = {Trials},
   title = {Training and education on inclusivity in clinical trials-the SENSITISE project},
   url = {https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-024-08150-5},
   volume = {25},
   year = {2024}
}

TY  - JOUR
ID  - 2417979
AU  - Shiely, Frances - Rychlíčková, Jitka - Kubiak, Christine - Čechová, Zora - Esdaile, Martina - Treweek, Shaun
PY  - 2024
TI  - Training and education on inclusivity in clinical trials-the SENSITISE project
JF  - Trials
VL  - 25
IS  - 1
SP  - 1-2
EP  - 1-2
PB  - Elsevier
SN  - 17456215
KW  - clinical trials
KW  - training
KW  - education
UR  - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-024-08150-5
N2  - There have been calls globally to improve participation in clinical trials of groups that traditionally have been under-represented. These under-served groups are populations under-represented or disengaged from medical research or services despite having a disproportionately high healthcare burden. INCLUDE, a 2017 initiative from the UK’s National Institute of Health Research (NIHR), has defined and identified under-served groups in clinical trials (elderly, ethnic minorities, the socioeconomically disadvantaged, pregnant and lactating women, the LGBTQ+ community, rural dwellers, those with comorbidities including disability, mental health conditions or cognitive impairment, amongst others) and barriers for recruitment. Trial conclusions cannot with certainty support treatment decisions (or mode of treatment delivery) for those not represented in the trial. This perpetuates inequality, is immoral and represents bad science. It can also lead to general distrust in research amongst under-served groups. Designing and conducting clinical trials is a complex task, and all involved agree that investigators need adequate training to perform their duties. Despite this, there is no formal training on inclusivity in clinical trials available globally.
ER  -

SHIELY, Frances; Jitka RYCHLÍČKOVÁ; Christine KUBIAK; Zora ČECHOVÁ; Martina ESDAILE a Shaun TREWEEK. Training and education on inclusivity in clinical trials-the SENSITISE project. \textit{Trials}. LONDON: Elsevier, 2024, roč.~25, č.~1, s.~1-2. ISSN~1745-6215. Dostupné z: https://doi.org/10.1186/s13063-024-08150-5.

Přehled o publikaci