Raman microspectroscopy and laser-induced breakdown
spectroscopy for the analysis of polyethylene microplastics in
human soft tissues

J 2024

Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues

PAROBKOVA, Viktoria, Daniel HOLUB, Martin KIZOVSKY, Gabriela KALCIKOVA, Ula ROZMAN et. al.

Základní údaje

Originální název

Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues

Autoři

PAROBKOVA, Viktoria (203 Česká republika), Daniel HOLUB (203 Česká republika), Martin KIZOVSKY (203 Česká republika), Gabriela KALCIKOVA (203 Česká republika), Ula ROZMAN, Milan URÍK (703 Slovensko, domácí), Karel NOVOTNÝ (203 Česká republika, domácí), Ota SAMEK (203 Česká republika), Tomas ZIKMUND (203 Česká republika), Pavel PORIZKA (203 Česká republika) a Jozef KAISER (203 Česká republika)

Vydání

Heliyon, CAMBRIDGE, CELL PRESS, 2024, 2405-8440

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10406 Analytical chemistry

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.000 v roce 2022

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.heliyon.2024.e37844

UT WoS

001316877400001

Klíčová slova anglicky

Health hazards; Exposure; Plastic pollution; Polyethylene; Microplastics; Tissue analysis; Human tonsils; Raman spectroscopy; Laser-induced breakdown spectroscopy; LIBS

Štítky

14110319

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 1. 10. 2024 10:35, Mgr. Tereza Miškechová

Anotace

V originále

People are exposed to microplastics (MPs) on a large scale in everyday life. However, it is not clear whether MPs can also be distributed and retained in certain tissues. Therefore, the development of analytical methods capable of detecting MPs in specific human organs/tissues is of utmost importance. In this study, the use and combination of spectroscopic techniques, namely Raman microspectroscopy and laser-induced breakdown spectroscopy (LIBS), was tested for the detection of polyethylene (PE) MPs in human tonsils. Preliminary results showed that Raman microspectroscopy was able to detect MPs down to 1 mu m in size and LIBS down to 10 mu m. In the next step, human tonsils were spiked with PE MPs, and digested. The filtered particles were analyzed using Raman microspectroscopy and LIBS, and complemented by X-ray fluorescence (XRF). The results showed that Raman microspectroscopy could reliably detect PE MPs in spiked human tonsils, while LIBS and XRF served as a reference analytical method to characterize particles that could not be classified by Raman microspectroscopy for their non-organic origin. The results of this study, supported by a current feasibility study conducted on clinical samples, demonstrated the reliability and feasibility of this approach for monitoring MPs in biotic samples.

Návaznosti

MUNI/A/1498/2023, interní kód MU

Název: Personalizovaný přístup v léčbě nedoslýchavosti u dětí s kochleárním implantátem

Investor: Masarykova univerzita, Personalizovaný přístup v léčbě nedoslýchavosti u dětí s kochleárním implantátem

Citovat

PAROBKOVA, Viktoria, Daniel HOLUB, Martin KIZOVSKY, Gabriela KALCIKOVA, Ula ROZMAN, Milan URÍK, Karel NOVOTNÝ, Ota SAMEK, Tomas ZIKMUND, Pavel PORIZKA a Jozef KAISER. Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues. Heliyon. CAMBRIDGE: CELL PRESS, 2024, roč. 10, č. 18, s. 1-11. ISSN 2405-8440. Dostupné z: https://dx.doi.org/10.1016/j.heliyon.2024.e37844.

@article{2439077,
   author = {Parobkova, Viktoria and Holub, Daniel and Kizovsky, Martin and Kalcikova, Gabriela and Rozman, Ula and Urík, Milan and Novotný, Karel and Samek, Ota and Zikmund, Tomas and Porizka, Pavel and Kaiser, Jozef},
   article_location = {CAMBRIDGE},
   article_number = {18},
   doi = {http://dx.doi.org/10.1016/j.heliyon.2024.e37844},
   keywords = {Health hazards; Exposure; Plastic pollution; Polyethylene; Microplastics; Tissue analysis; Human tonsils; Raman spectroscopy; Laser-induced breakdown spectroscopy; LIBS},
   language = {eng},
   issn = {2405-8440},
   journal = {Heliyon},
   title = {Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues},
   url = {https://www.sciencedirect.com/science/article/pii/S2405844024138753?via%3Dihub},
   volume = {10},
   year = {2024}
}

TY  - JOUR
ID  - 2439077
AU  - Parobkova, Viktoria - Holub, Daniel - Kizovsky, Martin - Kalcikova, Gabriela - Rozman, Ula - Urík, Milan - Novotný, Karel - Samek, Ota - Zikmund, Tomas - Porizka, Pavel - Kaiser, Jozef
PY  - 2024
TI  - Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues
JF  - Heliyon
VL  - 10
IS  - 18
SP  - 1-11
EP  - 1-11
PB  - CELL PRESS
SN  - 24058440
KW  - Health hazards
KW  - Exposure
KW  - Plastic pollution
KW  - Polyethylene
KW  - Microplastics
KW  - Tissue analysis
KW  - Human tonsils
KW  - Raman spectroscopy
KW  - Laser-induced breakdown spectroscopy
KW  - LIBS
UR  - https://www.sciencedirect.com/science/article/pii/S2405844024138753?via%3Dihub
N2  - People are exposed to microplastics (MPs) on a large scale in everyday life. However, it is not clear whether MPs can also be distributed and retained in certain tissues. Therefore, the development of analytical methods capable of detecting MPs in specific human organs/tissues is of utmost importance. In this study, the use and combination of spectroscopic techniques, namely Raman microspectroscopy and laser-induced breakdown spectroscopy (LIBS), was tested for the detection of polyethylene (PE) MPs in human tonsils. Preliminary results showed that Raman microspectroscopy was able to detect MPs down to 1 mu m in size and LIBS down to 10 mu m. In the next step, human tonsils were spiked with PE MPs, and digested. The filtered particles were analyzed using Raman microspectroscopy and LIBS, and complemented by X-ray fluorescence (XRF). The results showed that Raman microspectroscopy could reliably detect PE MPs in spiked human tonsils, while LIBS and XRF served as a reference analytical method to characterize particles that could not be classified by Raman microspectroscopy for their non-organic origin. The results of this study, supported by a current feasibility study conducted on clinical samples, demonstrated the reliability and feasibility of this approach for monitoring MPs in biotic samples.
ER  -

PAROBKOVA, Viktoria, Daniel HOLUB, Martin KIZOVSKY, Gabriela KALCIKOVA, Ula ROZMAN, Milan URÍK, Karel NOVOTNÝ, Ota SAMEK, Tomas ZIKMUND, Pavel PORIZKA a Jozef KAISER. Raman microspectroscopy and laser-induced breakdown spectroscopy for the analysis of polyethylene microplastics in human soft tissues. \textit{Heliyon}. CAMBRIDGE: CELL PRESS, 2024, roč.~10, č.~18, s.~1-11. ISSN~2405-8440. Dostupné z: https://dx.doi.org/10.1016/j.heliyon.2024.e37844.

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